| Texto completo | |
| Autor(es): |
Pontes, Lauany Mazzon
;
de Faria, Joao Vitor Gonsalves
;
Reinaldi, Julia Santana
;
Magrin, Patricia Paula Araujo
;
Silveira, Natalia Nascimento
;
dos Santos, Raquel Alves
;
Rocha, Lucas Alonso
;
Verelst, Marc
;
Nassar, Eduardo Jose
Número total de Autores: 9
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Journal of Luminescence; v. 292, p. 10-pg., 2026-04-01. |
| Resumo | |
Calcium phosphates (CPs) have been widely used in biomedical applications due to their excellent biocompatibility, crystalline structure, and low toxicity. These characteristics allow structural modifications during synthesis, such as substitution with lanthanide ions, which confer luminescent properties to the matrix. In this study, a CP matrix was synthesized from phosphoric acid and calcium nitrate, with partial substitution of calcium ions by the lanthanide ions erbium (Er3+) and ytterbium (Yb3+) at 1 % and 10 % concentrations, respectively. Characterization by X-ray diffraction revealed a mixture of CP phases. Vibrational spectroscopy in the infrared region identified characteristic matrix bands. Photoluminescence analysis showed bands attributed to Er3+ in the visible and infrared regions. In upconversion energy analyses, using 980 nm laser excitation with power variation between 490 and 1000 mW, more intense emissions were observed in the green region. The increase in power suggested possible thermal excitation of electrons. In temperature variation experiments (25-100 degrees C), the material demonstrated and confirmed significant thermal sensitivity, indicating potential for application in optical temperature sensing. Cytotoxicity assays indicated no impairment of cell viability at any of the tested concentrations, with behavior similar to the negative control at 24, 48, and 72 h. (AU) | |
| Processo FAPESP: | 19/26439-5 - Nanopartículas obtidas via sol-gel contendo íons lantanídeos para aplicação multimodal em Medicina |
| Beneficiário: | Eduardo José Nassar |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 25/14942-5 - Global Congress on Biomaterials and Regenerative Medicine (Biomaterials Summit-2025) |
| Beneficiário: | Eduardo José Nassar |
| Modalidade de apoio: | Auxílio à Pesquisa - Reunião - Exterior |