| Texto completo | |
| Autor(es): |
Resende, Glaucimar Alex Passos
;
Ferraz, Sofia Madruga Marcondes
;
Bressan, Lucas Paines
;
de Oliveira, Isadora
;
Nazario, Thiago
;
de Araujo, Lucas Pessoa
;
Hantao, Leandro Wang
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF CHROMATOGRAPHY OPEN; v. 8, p. 10-pg., 2025-10-22. |
| Resumo | |
Electronic cigarettes (e-cigarettes) have gained global popularity, raising public health concerns due to the limited regulation and chemical complexity of e-liquids and their aerosols. This study presents the compositional analysis of volatile and semi-volatile organic compounds in 34 commercial e-liquid samples and their corresponding aerosols using headspace solid-phase microextraction (HS-SPME) and comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GCxGC-MS). The HS-SPME method was optimized using a central composite design (CCD), which established the ideal extraction conditions. One hundred twenty-six compounds were identified in the e-liquids. Chemometric analysis revealed distinct flavor profiles. The occurrence of concerning aldehydes, including benzaldehyde and (E)-cinnamaldehyde, was confirmed in the samples. The study of compounds generated when the e-liquids were heated at various temperatures (190-270 degrees C) and durations (3-30 min) showed the formation of harmful and potentially harmful constituents (HPHCs), including furfural, glycidol, and diacetyl, under specific conditions. Principal component analysis (PCA) of the aerosol data revealed the impact of heating time on the volatilization of both major e-liquid components and lowerconcentration flavoring compounds. Overall, this study demonstrated the potential of GCxGC-MS for characterizing e-liquids and enhanced our understanding of toxic compound formation during the heating of e-liquids. (AU) | |
| Processo FAPESP: | 22/07406-1 - Emprego de ferramentas analíticas avançadas para avaliação do potencial de obtenção de bio-óleo a partir de bagaço de cana e estudo do melhoramento catalítico com vista a aplicação industrial |
| Beneficiário: | Leandro Wang Hantao |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |