Diabetes and sleep: A complex cause-and-effect relationship

Autor(es)

Barone, Mark T. U. ^[1] ; Menna-Barreto, Luiz ^[2]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Fisiol & Biofis, BR-05508900 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Escola Artess Ciencias & Humanidades, BR-05508900 Sao Paulo - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Diabetes Research and Clinical Practice; v. 91, n. 2, p. 129-137, FEB 2011.
• Citações Web of Science: 57

Resumo

Strong associations of diabetes with sleep impairment have been frequently reported. In the present review, we discuss current evidence and hypotheses for how type 1 and type 2 diabetes mellitus are associated with sleep impairment. This association may be described as a vicious circle, where sleep disorders favor the development of type 2 diabetes or exacerbate the metabolic control of both types of diabetes, whereas diabetes itself, especially when associated with poor metabolic control, is often followed by sleep disorders. In this review, novel findings concerning the neuro-endocrine-metabolic mediation of the mentioned circle are highlighted. Understanding how this association occurs, the impact of sleep impairment on diabetes, and the impact of diabetes on the development or exacerbation of sleep disorders should lead to potential new therapeutic strategies for treating both conditions. (C) 2010 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 08/11026-2 - Ciclo vigília /sono em portadores de diabetes mellitus tipo 1
• Beneficiário: Luiz Silveira Menna Barreto
• Modalidade de apoio: Auxílio à Pesquisa - Regular