Ethanol Wet-bonding Challenges Current Anti-degradation Strategy

Autor(es)

Sadek, F. T. ^[1] ; Braga, R. R. ^[1] ; Muench, A. ^[1] ; Liu, Y. ^[2] ; Pashley, D. H. ^[3] ; Tay, F. R. ^{[3, 4]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Dent, Dept Dent Mat, BR-05508 Sao Paulo - Brazil

^[2] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Stomatol, Wuhan 430074 - Peoples R China

^[3] Med Coll Georgia, Sch Dent, Dept Oral Biol, Augusta, GA 30912 - USA

^[4] Med Coll Georgia, Sch Dent, Dept Endodont, Augusta, GA 30912 - USA

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF DENTAL RESEARCH; v. 89, n. 12, p. 1499-1504, DEC 2010.
• Citações Web of Science: 81

Resumo

The long-term effectiveness of chlorhexidine as a matrix metalloproteinase (MMP) inhibitor may be compromised when water is incompletely removed during dentin bonding. This study challenged this anti-bond degradation strategy by testing the null hypothesis that wet-bonding with water or ethanol has no effect on the effectiveness of chlorhexidine in preventing hybrid layer degradation over an 18-month period. Acid-etched dentin was bonded under pulpal pressure simulation with Scotchbond MP and Single Bond 2, with water wet-bonding or with a hydrophobic adhesive with ethanol wet-bonding, with or without pre-treatment with chlorhexidine diacetate (CHD). Resin-dentin beams were prepared for bond strength and TEM evaluation after 24 hrs and after aging in artificial saliva for 9 and 18 mos. Bonds made to ethanol-saturated dentin did not change over time with preservation of hybrid layer integrity. Bonds made to CHD pre-treated acid-etched dentin with commercial adhesives with water wet-bonding were preserved after 9 mos but not after 18 mos, with severe hybrid layer degradation. The results led to rejection of the null hypothesis and highlight the concept of biomimetic water replacement from the collagen intrafibrillar compartments as the ultimate goal in extending the longevity of resin-dentin bonds. (AU)

• Processo FAPESP: 07/55117-9 - Desenvolvimento de técnicas alternativas para melhorar a adesão e a longevidade de restaurações em compósito utilizando sistemas adesivos hidrofóbicos
• Beneficiário: Fernanda Tranchesi Sadek
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado