Digital subtraction radiographic analysis of the combination of bioabsorbable membrane and bovine morphogenetic protein pool in human periodontal infrabony defects

Autor(es)

Machado Guimaraes, Maria do Carmo ^[1] ; Passanezi, Euloir ^[2] ; Passanezi Sant'ana, Adriana Campos ^[2] ; Aguiar Greghi, Sebastiao Luiz ^[2] ; Taba Junior, Mario ^[3]

Afiliação do(s) autor(es)

^[1] Univ Brasilia, Dept Odontol, Periodont Div, BR-70910900 Brasilia, DF - Brazil

^[2] Univ Sao Paulo, Dept Prosthodont, Bauru Sch Dent, Bauru, SP - Brazil

^[3] Univ Sao Paulo, Dept Oral & Maxillofacial Surg & Traumatol & Peri, Ribeirao Preto Dent Sch, BR-14049 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Applied Oral Science; v. 18, n. 4, p. 379-384, JUL-AUG 2010.
• Citações Web of Science: 5

Resumo

OBJECTIVES: This study assessed the bone density gain and its relationship with the periodontal clinical parameters in a case series of a regenerative therapy procedure. MATERIAL AND METHODS: Using a split-mouth study design, 10 pairs of infrabony defects from 15 patients were treated with a pool of bovine bone morphogenetic proteins associated with collagen membrane (test sites) or collagen membrane only (control sites). The periodontal healing was clinically and radiographically monitored for six months. Standardized pre-surgical and 6-month postoperative radiographs were digitized for digital subtraction analysis, which showed relative bone density gain in both groups of 0.034 ± 0.423 and 0.105 ± 0.423 in the test and control group, respectively (p>0.05). RESULTS: As regards the area size of bone density change, the influence of the therapy was detected in 2.5 mm² in the test group and 2 mm² in the control group (p>0.05). Additionally, no correlation was observed between the favorable clinical results and the bone density gain measured by digital subtraction radiography (p>0.05). CONCLUSIONS: The findings of this study suggest that the clinical benefit of the regenerative therapy observed did not come with significant bone density gains. Long-term evaluation may lead to a different conclusions. (AU)

• Processo FAPESP: 98/13005-9 - Avaliacao clinica e radiografica de lesoes periodontais infra-osseas em humanos tratadas com proteinas morfogeneticas bovinas e membrana de colageno bovino.
• Beneficiário: Maria do Carmo Machado Guimaraes
• Modalidade de apoio: Bolsas no Brasil - Doutorado