Variation at the Est3 locus and adaptability to organophosphorous compounds in Zaprionus indianus populations

Autor(es)

da Conceicao Galego, Luis Gustavo ^[1] ; Aparecida Carareto, Claudia Marcia ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ, UNESP, BR-15054000 Sao Jose Do Rio Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Entomologia Experimentalis et Applicata; v. 134, n. 1, p. 97-105, JAN 2010.
• Citações Web of Science: 3

Resumo

Carboxylesterases are enzymes often associated with insect resistance to insecticides. The Est3 locus of Zaprionus indianus Gupta (Diptera: Drosophilidae) harbors four alleles that encode carboxylesterases with potentially detoxifying roles. In this study, we propose a model of resistance to insecticides in Z. indianus based on the adaptability of the Est3 locus inferred from the spread of its alleles over 27 generations in experimental populations, and their frequencies in field populations, which were either exposed or unexposed to the organophosphorous insecticide malathion. The increase in the frequency of this allele in experimental populations, and its high prevalence in field populations exposed to organophosphorous insecticides suggest that natural selection favors individuals with the Est3-3 allele. The low frequency of this allele in unexposed field populations, and the low productivity of Est3-3 homozygotes indicate that an adaptive cost is associated with this allele. The existence of a marker locus for insecticide resistance in Z. indianus makes it possible to use this species as a bioindicator for monitoring the excessive use of organophosphorous products and the emergence of resistance, and to devise strategies for the management of agricultural pests. (AU)

• Processo FAPESP: 04/05235-7 - Análise da variação populacional de polimorfismos aloenzimáticos e sua adaptabilidade em Zaprionus indianus (Diptera: Drosophilidae)
• Beneficiário: Claudia Marcia Aparecida Carareto
• Modalidade de apoio: Auxílio à Pesquisa - Regular