Transcriptional Processing of the pst Operon of Escherichia coli

Autor(es)

Aguena, Meire ^[1] ; Spira, Beny ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Ciencias, Dept Microbiol, BR-05508900 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Current Microbiology; v. 58, n. 3, p. 264-267, MAR 2009.
• Citações Web of Science: 13

Resumo

The pst operon of Escherichia coli is composed of five genes that encode a high-affinity phosphate transport system. pst belongs to the PHO regulon, which is a group of genes and operons that are induced in response to phosphate limitation. The pst operon also has a regulatory role in the repression of PHO genes' transcription under phosphate excess conditions. Transcription of pst is initiated at the promoter located upstream to the first gene, pstS. Immediately after its synthesis, the primary transcript of pst is cleaved into shorter mRNA molecules in a ribonuclease E-dependent manner. Other ribonucleases, such as RNase III and MazF, do not play a role in pst mRNA processing. RNase E is thus at least partially responsible for processing the pst primary transcript. (AU)

• Processo FAPESP: 02/04070-9 - Análise transcricional do operon pst de Escherichia coli
• Beneficiário: Meire Aguena
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto