Cell Culture on PCL/PLGA Blends

Autor(es)

Lucchesi, Carolina ^{[1, 2]} ; Barbanti, Samuel H. ^{[2, 3]} ; Joazeiro, Paulo P. ^[1] ; Duek, Eliana A. R. ^{[2, 3]}

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Univ Campinas, Dept Histol & Embriol, Inst Biol, BR-13083863 Campinas, SP - Brazil

^[2] Pontificia Univ Catolica Sao Paulo, Ctr Ciencias Med & Biol, Lab Biomat, BR-18030230 Sorocaba, SP - Brazil

^[3] Univ Estadual Campinas UNICAMP, Fac Engn Mecan, Dept Engn Mat, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Applied Polymer Science; v. 115, n. 5, p. 2609-2615, MAR 5 2010.
• Citações Web of Science: 6

Resumo

Bioresorbable polymers have been studied as support for cell culture in the tissue engineering area. Osteoblastic cells were cultivated on poly(epsilon-caprolactone), poly(lactic acid-co-glycolic acid), and (70/30), (50/50), and (30/70) blends. Cytotoxicity and cell adhesion assays and scanning electronic microscopy studies were described. The cells presented significant growth on the blends, showing no cytotoxic response. Results indicated that these blends are promising as devices for bone tissue applications. (C) 2009 Wiley Periodicals, Inc. I Appl Polym Sci 115:2609-2615,2010 (AU)

• Processo FAPESP: 03/07352-8 - Estruturas tridimensionais de plga e pcl: estudo da degradacao in vitro, biocompatibilidade e como suporte para cultura de osteoblastos.
• Beneficiário: Eliana Aparecida de Rezende Duek
• Modalidade de apoio: Auxílio à Pesquisa - Regular