Permethrin-induced morphological changes in oocytes of Rhipicephalus sanguineus (Acari: Ixodidae) semi-engorged females

Autor(es)

Roma, Gislaine Cristina ^[1] ; Scopinho Furqium, Karim Christina ^[2] ; Bechara, Gervasio Henrique ^[2] ; Camargo-Mathias, Maria Izabel ^[1]

Afiliação do(s) autor(es)

^[1] UNESP, Univ Estadual Paulista Julio Mesquita Filho, Inst Biociencias, Dept Biol, BR-13506900 Rio Claro, SP - Brazil

^[2] UNESP, Fac Ciencias Agr & Vet, Dept Patol Vet, BR-14884900 Jaboticabal, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Food and Chemical Toxicology; v. 48, n. 3, p. 825-830, MAR 2010.
• Citações Web of Science: 36

Resumo

The permethrin, active ingredient of the Advantage (R) Max3 - Bayer, has been widely used in the chemical control of ticks. These ectoparasites are one of the most important animal groups that cause serious damage to their hosts. This study evaluated the toxic effects of permethrin in oocytes of Rhipicephalus sanguineus; semi-engorged females subjected to four treatments: group I (control - distilled water), group II (206 ppm of permethrin), group III (1031 ppm of permethrin) and group IV (2062 ppm of permethrin). Results demonstrated that permethrin is a potent chemical agent causing major structural changes in oocytes, such as emergence of large vacuolated cytoplasm regions, reducing the amount of yolk granules and decreasing the size of oocytes, culminating with cell death. As reported in the literature, these oocytes changes, besides affect the tick nervous system, also drastically reduce or prevent the reproduction process in females of R. sanguineus ticks subjected to this compound. (C) 2009 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 07/57809-5 - Estudo morfológico dos ovários de carrapatos Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) e do sangue periférico de camundongos, ambos submetidos ao piretróide permetrina (ingrediente ativo do Advantage Max3, Bayer)
• Beneficiário: Gislaine Cristina Roma
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 07/59020-0 - Estudo da morfo-histologia externa e interna (sistemas: salivar, produtivo e digestório) de três espécies de carrapatos de importância médica veterinária (Acari - Ixodidae)
• Beneficiário: Maria Izabel Souza Camargo
• Modalidade de apoio: Auxílio à Pesquisa - Regular