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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Conventional and Doppler ultrasound for the differentiation of benign and malignant canine mammary tumours

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Autor(es):
Feliciano, M. A. R. [1] ; Vicente, W. R. R. [1] ; Silva, M. A. M. [1]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ UNESP, Dept Anim Reprod, Coll Agr & Vet Sci, Sao Paulo - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF SMALL ANIMAL PRACTICE; v. 53, n. 6, p. 332-337, JUN 2012.
Citações Web of Science: 22
Resumo

Objectives: The aim of this study was to evaluate the sensitivity of conventional and Doppler ultrasound for differentiation of benign and malignant mammary tumours in female dogs. Methods: Mammary tumours were evaluated from 60 animals and divided into two distinct groups, group 1 (benign tumours) and group 2 (malignant tumours). The tumours were assessed by conventional ultrasound, Doppler ultrasound mode, histopathology and immunohistochemical detection of vascular endothelial growth factor. Results: Conventional ultrasound examination was found to be ineffective in separating tumours into the two experimental groups. Similarly, using colour-flow Doppler ultrasound, no correlation was found between the presence of vascularisation and its characteristics between the two groups. Triplex Doppler ultrasound yielded average maximum velocities of 28.71 cm/s for malignant and 19.91 cm/s for benign tumours, which were significantly different (P=0.01). For vascular endothelial growth factor, an average score of 2.22 was found for group 2 and 1.66 for group 1 (P=0.03). Positive correlations were found between vascular endothelial growth factor and presence of vascularisation (P=0.04 and r=0.3658) and between vascular endothelial growth factor and maximum velocity (P=0.03 and r=0.3913). Clinical Significance: Doppler evaluation may be used to predict malignancy of mammary tumours in bitches. (AU)

Processo FAPESP: 09/51195-0 - Diagnóstico ultra-sonográfico convencional e modo Doppler em cores na avaliação e caracterização da neoplasia mamária em cadelas
Beneficiário:Wilter Ricardo Russiano Vicente
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 08/08180-0 - Ultrassonografia convencional e modo Doppler em cores e power na avaliação da neoplasia mamária em cadelas
Beneficiário:Marcus Antônio Rossi Feliciano
Modalidade de apoio: Bolsas no Brasil - Doutorado