Voltammetric determination of Delta(9)-THC in glassy carbon electrode: An important contribution to forensic electroanalysis

Autor(es)

Balbino, Marco Antonio ^[1] ; Teles de Menezes, Matheus Manoel ^[1] ; Eleoterio, Izabel Cristina ^[1] ; Saczk, Adelir Aparecida ^[2] ; Okumura, Leonardo Luiz ^[3] ; Tristao, Heloisa Maria ^[4] ; de Oliveira, Marcelo Firmino ^[1]

Afiliação do(s) autor(es)

^[1] Univ Ribeirao Preto, Fac Filosofia Ciencias & Letras, Dept Quim, BR-14040901 Ribeirao Preto, SP - Brazil

^[2] Univ Fed Lavras, Dept Quim, BR-37200000 Lavras, MG - Brazil

^[3] Univ Fed Vicosa, Dept Quim, BR-36570000 Vicosa, MG - Brazil

^[4] Nucl Pericias Criminalisticas Ribeira Preto, BR-14015040 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Forensic Science International; v. 221, n. 1-3, p. 29-32, SEP 10 2012.
• Citações Web of Science: 10

Resumo

A new voltammetric method for the determination of Delta(9)-tetrahydrocannabinol (Delta(9)-THC) is described. The voltammetric experiments were accomplished in N-N dimethylformamide/water (9: 1, v/v), using tetrabutylammonium tetrafluoroborate (TBATFB) 0.1 mol/L as supporting electrolyte and a glassy carbon disk electrode as the working electrode. The anodic peak current was observed at 0.0 V (vs. Ag/AgCl) after a 30 s pre-concentration step under an applied potential of -1.2 V (vs. Ag/AgCl). A linear dependence of Delta(9)-THC detection was obtained in the concentration range 2.4-11.3 ng/mL, with a linear correlation coefficient of 0.999 and a detection limit of 0.34 ng/mL. The voltammetric method was used to measure the content of Delta(9)-THC in samples (hemp and hashish) confiscated by the police. The elimination of chemical interferences from the samples was promptly achieved through prior purification using the TLC technique, by employing methanol/water (4: 1, v/v) as the mobile phase. The results showed excellent correlation with results attained by HPLC. (C) 2012 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 07/54204-5 - Desenvolvimento de sensores eletroquimicos e piezoeletricos para ciencia forense: determinacao de cocaina e delta-9-tetraidrocanabiol.
• Beneficiário: Marcelo Firmino de Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Regular