| Texto completo | |
| Autor(es): |
de Moura, Nivaldo R.
[1]
;
Cury-Boaventura, Maria F.
[1]
;
Santos, Vinicius C.
[1]
;
Levada-Pires, Adriana C.
[2]
;
Bortolon, Jose Ricardo
[1]
;
Fiamoncini, Jarlei
[2]
;
Pithon-Curi, Tania C.
[1]
;
Curi, Rui
[2]
;
Hatanaka, Elaine
[1]
Número total de Autores: 9
|
| Afiliação do(s) autor(es): | [1] Cruzeiro Univ, Inst Phys Act & Sport Sci ICAFE, Postgrad Program Human Movement Sci, Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, Sao Paulo - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | JOURNAL OF STRENGTH AND CONDITIONING RESEARCH; v. 26, n. 9, p. 2507-2514, SEP 2012. |
| Citações Web of Science: | 13 |
| Resumo | |
de Moura, NR, Cury-Boaventura, MF, Santos, VC, Levada-Pires, AC, Bortolon, JR, Fiamoncini, J, Pithon-Curi, TC, Curi, R, and Hatanaka, E. Inflammatory response and neutrophil functions in players after a futsal match. J Strength Cond Res 26(9): 2507-2514, 2012-Futsal players suffer injuries resulting from muscle fatigue and contact or collision among players. Muscle lesions can be detected by measuring muscle lesion markers such as creatine kinase (CK) and lactate dehydrogenase (LDH) in plasma. After an initial lesion, there is an increase in the plasma levels of C-reactive protein (CRP) and proinflammatory cytokines. These mediators may activate neutrophils and contribute to tissue damage and increase susceptibility to invasive microorganisms. In this study, we investigated the effect of a futsal match on muscle lesion markers, cytokines, and CRP in elite players. The basal and stimulated neutrophil responsiveness after a match was also evaluated based on measurements of neutrophil necrosis, apoptosis, phagocytic capacity, reactive oxygen species (ROS) production, and cytokines (tumor necrosis factor-alpha {[}TNF-alpha], interleukin {[}IL]-8, IL-1 beta, IL-10, and IL-1ra) production. Blood samples were taken from 16 players (26.4 +/- 3.2 years, 70.2 +/- 6.9 kg, 59.7 +/- 5.1 ml.kg(-1).min(-1), sports experience of 4.4 +/- 0.9 years) before and immediately after a match. Exercise increased the serum activities of CK (2.5-fold) and LDH (1.3-fold). Playing futsal also increased the serum concentrations of IL-6 (1.6-fold) and CRP (1.6-fold). The TNF-alpha, IL-1 beta, IL-8, IL-1ra, and IL-10 serum levels were not modified in the conditions studied. The futsal match induced neutrophil apoptosis, as indicated by phosphatidylserine externalization (6.0-fold). The exercise induced priming of neutrophils by increasing ROS (1.3-fold), TNF-alpha (5.8-fold), and IL-1 beta (4.8-fold) released in nonstimulated cells. However, in the stimulated condition, the exercise decreased neutrophil function, diminishing the release of ROS by phorbol myristate acetate-stimulated neutrophils (1.5-fold), and the phagocytic capacity (1.6-fold). We concluded that playing futsal induces inflammation, primes and activates neutrophils, and reduces the efficiency of neutrophil phagocytosis immediately after a match. (AU) | |
| Processo FAPESP: | 08/56105-7 - Instalacao e envolucao do processo inflamatorio em atletas de futsal: estudo em relacao as posicoes taticas |
| Beneficiário: | Nivaldo Ribeiro de Moura |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 09/06039-0 - Instalação e evolução do processo inflamatório em atletas de futsal: estudo em relação às posições táticas |
| Beneficiário: | Elaine Hatanaka Dermargos |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |