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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Culex quinquefasciatus Storage Proteins

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Autor(es):
Martins, Larissa A. [1] ; Fogaca, Andrea C. [1] ; Tania Bijovsky, A. [1] ; Carballar-Lejarazu, Rebeca [2] ; Marinotti, Osvaldo [2] ; Cardoso, Andre F. [1]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Ciencias Biomed, Dept Parasitol, BR-05508 Sao Paulo - Brazil
[2] Univ Calif Irvine, Dept Mol Biol & Biochem, Irvine, CA 92717 - USA
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: PLoS One; v. 8, n. 10 OCT 29 2013.
Citações Web of Science: 6
Resumo

Insect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes. Their transcripts are more abundant in larvae than in pupae and in adults. In fact, only four of these genes are transcribed in adults, two of which in blood-fed adult females but not in adult males. Transcripts corresponding to all Cx. quinquefasciatus storage proteins were detected by RTPCR, while mass spectrometric analysis of larval and pupal proteins identified all storage proteins with the exception of one encoded by Cq LSP1.8. Our results indicate that the identified Cx. quinquefasciatus storage protein-coding genes are candidates for identifying regulatory sequences for the development of molecular tools for vector control. (AU)

Processo FAPESP: 10/51241-0 - Culex quinquefasciatus: alguns aspectos da sua fisiologia
Beneficiário:Alcira Tania Bijovsky de Katzin
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 13/09211-4 - Culex quinquefasciatus: vitelogenina e suas proteases
Beneficiário:Alcira Tania Bijovsky de Katzin
Linha de fomento: Auxílio à Pesquisa - Regular