Antibiotic Detection in Urine Using Electrochemical Sensors Based on Vertically Aligned Carbon Nanotubes

Autor(es)

Moraes, Fernando C. ^[1] ; Silva, Tiago A. ^[1] ; Cesarino, Ivana ^[1] ; Lanza, Marcos R. V. ^[1] ; Machado, Sergio A. S. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Electroanalysis; v. 25, n. 9, p. 2092-2099, SEP 2013.
• Citações Web of Science: 16

Resumo

A sensitive way to determine levofloxacin using a sensor based on vertical aligned carbon nanotubes is described. The morphology and the electrochemical performance of the electrodes were characterised by atomic force microscopy, cyclic voltammetry and square wave voltammetry. A scan-rate study and electrochemical impedance spectroscopy showed that the levofloxacin oxidation product is adsorbed on the electrode surface. Differential pulse voltammetry in phosphate-buffer solution allowed the development of a method to determine levofloxacin levels in the range of 1.0-10.0 mu molL(-1), with a detection limit of 75.2nmolL(-1). The proposed sensor was successfully applied in the determination of levofloxacin in urine, and the obtained results were in full agreement with those from the HPLC procedure. (AU)

• Processo FAPESP: 10/11049-2 - Desenvolvimento e aplicação de sensores eletroquímicos baseados em nanotubos de carbono alinhados para a detecção de interferentes endócrinos em amostras ambientais
• Beneficiário: Fernando Cruz de Moraes
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado