DSM-5 latent classes of alcohol users in a population-based sample: Results from the Sao Paulo Megacity Mental Health Survey, Brazil

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Castaldelli-Maia, Joao Mauricio ^{[1, 2, 3]} ; Silveira, Camila M. ^{[1, 2]} ; Siu, Erica R. ^[1] ; Wang, Yuan-Pang ^[1] ; Milhoranca, Igor A. ^[1] ; Alexandrino-Silva, Clovis ^[1] ; Borges, Guilherme ^{[4, 5]} ; Viana, Maria C. ^{[6, 7]} ; Andrade, Arthur G. ^{[2, 3]} ; Andrade, Laura H. ^[1] ; Martins, Silvia S. ^[8]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Med, Dept & Inst Psychiat, Sect Psychiat Epidemiol LIM 23, BR-05403 Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Med, Dept & Inst Psychiat, Interdisciplinary Grp Studies Alcohol & Drugs, BR-05403 Sao Paulo - Brazil

^[3] Fundacao ABC, Sch Med, Dept Neurosci, BR-09060 Santo Andre, SP - Brazil

^[4] Natl Inst Psychiat, Mexico City 14370, DF - Mexico

^[5] Metropolitan Autonomous Univ, Mexico City 14370, DF - Mexico

^[6] Univ Fed Espirito Santo, Dept Social Med, BR-29040 Vitoria, ES - Brazil

^[7] Univ Fed Espirito Santo, Postgrad Program Publ Hlth, BR-29040 Vitoria, ES - Brazil

^[8] Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY 10032 - USA

• Tipo de documento: Artigo Científico
• Fonte: DRUG AND ALCOHOL DEPENDENCE; v. 136, p. 92-99, MAR 1 2014.
• Citações Web of Science: 10

Resumo

Background: We aimed to identify different categorical phenotypes based upon the DSM-V criteria of alcohol use disorders (AUD) among alcohol users who had at least one drink per week in the past year (n = 948). Methods: Data are from the Sao Paulo Megacity Mental Health Survey collected in 2005-2007, as part of the World Mental Health Survey Initiative. A latent class analysis of the 11 DSM-5-AUD criteria was performed using Mplus, taking into account complex survey design features. Weighted logistic regression models were used to examine demographic correlates of the DSM-5-AUD latent classes. Results: The best latent-class model was a three-class model. We found a ``non-symptomatic class{''} (69.7%), a ``use in larger amounts class{''} (23.2%), defined by high probability (>70%) of the ``use in larger amounts{''} criterion only, and a ``high-moderate symptomatic class{''} (7.1%), defined by high-moderate probability of all the 11 AUD criteria. Compared to those in the non-symptomatic class, individuals in the ``high-moderate symptomatic class{''} were more likely to have been married, have lower educational attainment and to be unemployed or in non-regular/informal employment. Those on the ``use in larger amounts class{''} were more likely to have been married or never married. Conclusion: The two symptomatic classes clearly represented the dimensionality of the new proposed AUD criteria, and could be more specifically targeted by different prevention or treatment strategies. DSM-5-AUD has the advantage of shedding light on risky drinkers included in the ``use in larger amounts class{''}, allowing for preventive interventions, which will reach a large number of individuals. (C) 2013 Elsevier Ireland Ltd. All rights reserved. (AU)

• Processo FAPESP: 11/50517-4 - Identificação dos diferentes subgrupos de usuários de álcool e fatores associados na região metropolitana de São Paulo: diferenças entre gêneros, dados sociodemográficos e comorbidades psiquiátricas
• Beneficiário: Laura Helena Silveira Guerra de Andrade
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 03/00204-3 - Estudo epidemiológico dos transtornos psiquiátricos na região metropolitana de São Paulo: prevalências, fatores de risco e sobrecarga social e econômica
• Beneficiário: Laura Helena Silveira Guerra de Andrade
• Modalidade de apoio: Auxílio à Pesquisa - Temático