Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium

Autor(es):Mostrar menos -

Leoncini, Emanuele ^[1] ; Ricciardi, Walter ^[1] ; Cadoni, Gabriella ^[2] ; Arzani, Dario ^[1] ; Petrelli, Livia ^[2] ; Paludetti, Gaetano ^[2] ; Brennan, Paul ^[3] ; Luce, Daniele ^[4] ; Stucker, Isabelle ^[4] ; Matsuo, Keitaro ^[5] ; Talamini, Renato ^[6] ; La Vecchia, Carlo ^{[7, 8]} ; Olshan, Andrew F. ^[9] ; Winn, Deborah M. ^[10] ; Herrero, Rolando ^[3] ; Franceschi, Silvia ^[3] ; Castellsague, Xavier ^[11] ; Muscat, Joshua ^[12] ; Morgenstern, Hal ^{[13, 14, 15]} ; Zhang, Zuo-Feng ^{[16, 17]} ; Levi, Fabio ^[18] ; Dal Maso, Luigino ^[6] ; Kelsey, Karl ^[19] ; McClean, Michael ^[20] ; Vaughan, Thomas L. ^[21] ; Lazarus, Philip ^[12] ; Purdue, Mark P. ^[10] ; Hayes, Richard B. ^[22] ; Chen, Chu ^[21] ; Schwartz, Stephen M. ^[21] ; Shangina, Oxana ^[23] ; Koifman, Sergio ^[24] ; Ahrens, Wolfgang ^{[25, 26]} ; Matos, Elena ^[27] ; Lagiou, Pagona ^[28] ; Lissowska, Jolanta ^{[29, 30]} ; Szeszenia-Dabrowska, Neonila ^[31] ; Fernandez, Leticia ^[32] ; Menezes, Ana ^[33] ; Agudo, Antonio ^[34] ; Daudt, Alexander W. ^[35] ; Richiardi, Lorenzo ^[36] ; Kjaerheim, Kristina ^[37] ; Mates, Dana ^[38] ; Betka, Jaroslav ^{[39, 40]} ; Yu, Guo-Pei ^[41] ; Schantz, Stimson ^[41] ; Simonato, Lorenzo ^[42] ; Brenner, Hermann ^[43] ; Conway, David I. ^[44] ; Macfarlane, Tatiana V. ^[45] ; Thomson, Peter ^[46] ; Fabianova, Eleonora ^[47] ; Znaor, Ariana ^[48] ; Rudnai, Peter ^[49] ; Healy, Claire ^[50] ; Boffetta, Paolo ^{[51, 52]} ; Chuang, Shu-Chun ^[53] ; Lee, Yuan-Chin Amy ^[54] ; Hashibe, Mia ^[54] ; Boccia, Stefania ^{[1, 55]}

Afiliação do(s) autor(es):Mostrar menos -

^[1] Univ Cattolica Sacro Cuore, Sect Hyg, Inst Publ Hlth, Rome - Italy

^[2] Univ Cattolica Sacro Cuore, Inst Otorhinolaryngol, Rome - Italy

^[3] Int Agcy Res Canc, F-69372 Lyon - France

^[4] Ctr Res Epidemiol & Populat Hlth, INSERM, UMRS 1018, Villejuif - France

^[5] Aichi Canc Ctr Res Inst, Nagoya, Aichi - Japan

^[6] Ctr Riferimento Oncol IRCCS, Aviano - Italy

^[7] Univ Milan, Milan - Italy

^[8] IRCCS Ist Ric Farmacol Mario Negri, Milan - Italy

^[9] Univ N Carolina, Gillings Sch Global Publ Hlth, Chapel Hill, NC - USA

^[10] NCI, NIH, Bethesda, MD 20892 - USA

^[11] CIBER ESP, IDIBELL, ICO, Barcelona - Spain

^[12] Penn State Coll Med, Hershey, PA - USA

^[13] Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 - USA

^[14] Univ Michigan, Sch Publ Hlth, Dept Environm Hlth Sci, Ann Arbor, MI 48109 - USA

^[15] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 - USA

^[16] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Dept Epidemiol, Los Angeles, CA - USA

^[17] Jonsson Comprehens Canc Ctr, Los Angeles, CA 90034 - USA

^[18] Univ Lausanne Hosp, Canc Epidemiol Unit, Inst Social & Prevent Med IUMSP, Lausanne - Switzerland

^[19] Brown Univ, Providence, RI 02912 - USA

^[20] Boston Univ, Sch Publ Hlth, Boston, MA - USA

^[21] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 - USA

^[22] NYU, Sch Med, Div Epidemiol, New York, NY - USA

^[23] Russian Acad Med Sci, Canc Res Ctr, Moscow - Russia

^[24] Fundacao Oswaldo Cruz, Escola Nacl Saude Publ, Rio De Janeiro - Brazil

^[25] Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen - Germany

^[26] Univ Bremen, Dept Math & Comp Sci, D-28359 Bremen - Germany

^[27] Univ Buenos Aires, Inst Oncol Angel H Roffo, Buenos Aires, DF - Argentina

^[28] Univ Athens, Sch Med, GR-11527 Athens - Greece

^[29] M Sklodowska Curie Mem Canc Ctr, Dept Canc Epidemiol & Prevent, Warsaw - Poland

^[30] Inst Oncol, Warsaw - Poland

^[31] Inst Occupat Med, Lodz - Poland

^[32] Inst Oncol & Radiobiol, Havana - Cuba

^[33] Univ Fed Pelotas, Pelotas - Brazil

^[34] IDIBELL, Catalan Inst Oncol ICO, Barcelona - Spain

^[35] Hosp Clin Porto Alegre, Porto Alegre, RS - Brazil

^[36] Univ Turin, Dept Med Sci, Turin - Italy

^[37] Canc Registry Norway, Oslo - Norway

^[38] Natl Inst Publ Hlth, Bucharest - Romania

^[39] Charles Univ Prague, Dept Otorhinolaryngol Head & Neck Surg, Fac Med 1, Prague - Czech Republic

^[40] Univ Hosp Motol, Prague - Czech Republic

^[41] New York Eye & Ear Infirm, New York, NY 10003 - USA

^[42] Univ Padua, Padua - Italy

^[43] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg - Germany

^[44] Univ Glasgow, Sch Dent, Coll Med Vet & Life Sci, Glasgow, Lanark - Scotland

^[45] Univ Aberdeen, Sch Dent, Aberdeen - Scotland

^[46] Newcastle Univ, Sch Dent Sci, Newcastle Upon Tyne NE1 7RU, Tyne & Wear - England

^[47] Reg Author Publ Hlth, Banska Bystrica - Slovakia

^[48] Croatian Natl Canc Registry, Zagreb - Croatia

^[49] Natl Inst Environm Hlth, Budapest - Hungary

^[50] Univ Dublin Trinity Coll, Sch Dent Sci, Dublin 2 - Ireland

^[51] Mt Sinai Sch Med, Tisch Canc Inst, New York, NY - USA

^[52] Int Prevent Res Inst, Lyon - France

^[53] Univ London Imperial Coll Sci Technol & Med, London - England

^[54] Univ Utah, Sch Med, Dept Family & Prevent Med, Salt Lake City, UT 84112 - USA

^[55] IRCCS San Raffaele Pisana, Rome - Italy

• Tipo de documento: Artigo Científico
• Fonte: EUROPEAN JOURNAL OF EPIDEMIOLOGY; v. 29, n. 1, p. 35-48, JAN 2014.
• Citações Web of Science: 15

Resumo

Several epidemiological studies have shown a positive association between adult height and cancer incidence. The only study conducted among women on mouth and pharynx cancer risk, however, reported an inverse association. This study aims to investigate the association between height and the risk of head and neck cancer (HNC) within a large international consortium of HNC. We analyzed pooled individual-level data from 24 case-control studies participating in the International Head and Neck Cancer Epidemiology Consortium. Odds ratios (ORs) and 95 % confidence intervals (CIs) were estimated separately for men and women for associations between height and HNC risk. Educational level, tobacco smoking, and alcohol consumption were included in all regression models. Stratified analyses by HNC subsites were performed. This project included 17,666 cases and 28,198 controls. We found an inverse association between height and HNC (adjusted OR per 10 cm height = 0.91, 95 % CI 0.86-0.95 for men; adjusted OR = 0.86, 95 % CI 0.79-0.93 for women). In men, the estimated OR did vary by educational level, smoking status, geographic area, and control source. No differences by subsites were detected. Adult height is inversely associated with HNC risk. As height can be considered a marker of childhood illness and low energy intake, the inverse association is consistent with prior studies showing that HNC occur more frequently among deprived individuals. Further studies designed to elucidate the mechanism of such association would be warranted. (AU)

• Processo FAPESP: 01/01768-2 - Estudo internacional de fatores ambientais, vírus e câncer de cavidade oral e de laringe
• Beneficiário: José Eluf Neto
• Modalidade de apoio: Auxílio à Pesquisa - Regular