| Texto completo | |
| Autor(es): |
Maciel da Silva, Bosco Christiano
[1, 2]
;
Paula, Claudete Rodrigues
[1]
;
Auler, Marcos Ereno
[1]
;
Ruiz, Luciana da Silva
[1]
;
dos Santos, Jairo Ivo
[3]
;
Naomi Yoshioka, Marcia Cristina
[4]
;
Fabris, Alexandre
[5]
;
Martins Castro, Luiz Guilherme
[5, 6]
;
da Silva Duarte, Alberto Jose
[2]
;
Gambale, Walderez
[1]
Número total de Autores: 10
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Dept Microbiol, Lab Mycol, Biomed Sci Inst 2, ICB 2, BR-05403000 Sao Paulo - Brazil
[2] Univ Sao Paulo, Lab Med Invest Dermatol & Immunodeficiency LIM 56, Fac Med, BR-05403000 Sao Paulo - Brazil
[3] Univ Fed Santa Catarina, Dept Clin Anal, Florianopolis, SC - Brazil
[4] Ctr Reference & Training STD AIDS, Sao Paulo - Brazil
[5] Univ Sao Paulo, Clin Hosp, Fac Med, Div Dermatol, BR-05403000 Sao Paulo - Brazil
[6] Albert Einstein Israelite Hosp, Ctr Cutaneous Oncol, Sao Paulo - Brazil
Número total de Afiliações: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | MYCOSES; v. 57, n. 6, p. 371-376, JUN 2014. |
| Citações Web of Science: | 10 |
| Resumo | |
Over the past decades, more people became infected with human immunodeficiency virus (HIV) and developed acquired immunodeficiency syndrome (AIDS). Because of that the incidence of fungal infections rose dramatically. It happened because this virus can modify the course of fungal diseases, leading to altered clinical pictures. The aim of this study was to evaluate epidemiological and biological aspects of dermatophytosis in HIV-positive and AIDS patients living in the city of SAo Paulo, Brazil. A total of 84 (44 HIV-positive and 40 AIDS) patients were enrolled in this study. The patients were tested for dermatophyte infections, as well as for the CD4(+)/CD8(+) and HIV viral load counts. Tinea unguium was most frequently observed in AIDS patients, whereas Tinea pedis was mostly observed in HIV-positive patients. The most frequent dermatophyte species was Trichophyton rubrum. CD4(+) counts and CD4(+)/CD8(+) ratios were not associated with a higher risk for dermatophytosis. On the other hand, viral load higher than 100000 copies/ml was associated with a higher frequency of dermatophytosis. The results suggest to that although dermatophytosis is common in HIV-positive and AIDS patients, the degree of immunosuppression does not seems to correlate with increased risk of this fungal infection. In addition, high viral load as a predictive risk factor for dermatophyte infection should be subject of further evaluations. (AU) | |
| Processo FAPESP: | 00/00668-1 - Estudo de amostras de Trichophyton rubrum isoladas de indivíduos infectados pelo vírus da imunodeficiência humana (HIV): morfologia, fatores de virulência e suscetibilidade a antifúngicos |
| Beneficiário: | Bosco Christiano Maciel da Silva |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |