| Texto completo | |
| Autor(es): |
Sturzbecher, M. J.
[1]
;
Tedeschi, W.
[2]
;
Cabella, B. C. T.
[3]
;
Baffa, O.
[4]
;
Neves, U. P. C.
[5]
;
de Araujo, D. B.
[6]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo. FFCLRP
[2] Univ Sao Paulo. FFCLRP
[3] Univ Sao Paulo. FFCLRP
[4] Univ Sao Paulo. FFCLRP
[5] Univ Sao Paulo. FFCLRP
[6] Univ Sao Paulo. FFCLRP
Número total de Afiliações: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Physics in Medicine and Biology; v. 54, n. 1, p. 161-174, JAN 7 2009. |
| Citações Web of Science: | 10 |
| Resumo | |
Functional magnetic resonance imaging (fMRI) data analysis has been carried out recently in the framework of information theory, by means of the Shannon entropy. As a natural extension, a method based on the generalized Tsallis entropy was developed to the analysis event-related (ER-fMRI), where a brief stimulus is presented, followed by a long period of rest. The new technique aims for spatial localization neuronal activity due to a specific task. This method does not require a priori hypothesis of the hemodynamic response function (HRF) shape and the linear relation between BOLD responses with the presented task. Numerical simulations were performed so as to determine the optimal values of the Tsallis q parameter and the number of levels, L. In order to avoid undesirable divergences of the Tsallis entropy, only positive q values were studied. Results from simulated data (with L = 3) indicated that, for q = 0.8, the active brain areas are detected with the highest performance. Moreover, the method was tested for an in vivo experiment and demonstrated the ability to discriminate active brain regions that selectively responded to a bilateral motor task. (AU) | |
| Processo FAPESP: | 05/03225-7 - Caracterizacao das respostas hemodinamicas de imagens funcionais por ressonancia magnetica e suas aplicacoes a pacientes com estenose carotidea e epilepsia. |
| Beneficiário: | Draulio Barros de Araujo |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |