METHOD OF OBTAINING A RETICULATED POLYESTER USING FREE PROCESS OF TOXIC REAGENTS, RETICULATED POLYESTER AND USE
| Document type: | Patente |
| Inventor(s): | Rubens Maciel Filho; André Luiz Jardini Munhoz; Anderson de Jesus Bonon; Maria Ingrid Rocha Barbosa Schiavon; Maria Regina Wolf Maciel; Natalia Lorena Parada Hernandez |
| Applicant: | Universidade Estadual de Campinas (UNICAMP) |
| Deposit date: | December 2015, 10 |
| INPI register: | |
| IPC: | C08G 63/78 |
(EN) The present invention relates to a process for synthesizing cross-linked polyester from the curing reaction of atoxic epoxidized plant oils, cross-linked polyester produced by said process and use thereof in the medical field, particularly for tissue engineering. To this end, non-toxic comonomers were used in the formulation and without the use of initiators and/or catalysts, making the material atoxic. Said epoxide resin with a toxic agent-free history was subsequently cured in the presence of citric acid, which was chosen as the curing agent due to its non-toxic nature. The curing reaction of epoxidized castor bean oil and citric acid allowed a cross-linked polyester to be produced from a formulation that is free of catalysts and/or initiators and toxic comonomers.
| FAPESP's process: | 09/16480-6 - Epoxy Biopolymers Synthesis from Renewable Sources for Building Biomedical Devices Using Rapid Prototyping Techniques and Biofabrication |
| Grantee: | Maria Ingrid Rocha Barbosa Schiavon |
| Principal Investigator: | Rubens Maciel Filho |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Faculdade de Engenharia Química (FEQ) |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |