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METHOD FOR SELECTING TICK ANTIGENS AND ANTIGENIC COMPOSITIONS AGAINST TICKS
| Document type: | Patente |
| Inventor(s): | Isabel Kinney Ferreira de Miranda Santos; José Marcos Chaves Ribeiro; Beatriz Rossetti Ferreira; Cecília José Veríssimo; Lucinda Giampietro Brandao; Sandra Regina Costa Maruyama; Elen Anatriello; Gustavo Rocha Garcia; Daniela Dantas Moré; Jesus Gilberto Valenzuela |
| Applicant: | Office Of Technology Transfer Of National Institutes Of Health ; Universidade de São Paulo (USP) |
| Deposit date: | September 2014, 26 |
| INPI register: | |
| IPC: | C12N15/12 C07K14/435 A61K39/00 A61P33/14 C12Q1/68 |
Abstract
The present invention relates to a method for selecting tick antigens, comprising the following steps: producing a tick transcriptome; synthetising the proteins; selecting the antigenic proteins; assessing the biological importance of the selected proteins; cloning and subcloning the DNA sequences relating to the selected proteins; synthetising antigens against ticks; and also, to antigenic compositions against ticks useful for mammals.
| Grantee: | João Santana da Silva |
| Principal Investigator: | João Santana da Silva |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) |
| Support type: | Regular Research Grants |
| FAPESP's process: | 06/04149-5 - Immunoscreening of Rhipicephalus microplus tick genes using reverse immunology to reveal novel anti-tick vaccine antigens |
| Grantee: | Beatriz Rossetti Ferreira |
| Principal Investigator: | Beatriz Rossetti Ferreira |
| Institution: | Universidade de São Paulo (USP). Escola de Enfermagem de Ribeirão Preto (EERP) |
| Support type: | Regular Research Grants |
| Grantee: | Isabel Kinney Ferreira de Miranda Santos |
| Principal Investigator: | Isabel Kinney Ferreira de Miranda Santos |
| Institution: | Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) |
| Support type: | Regular Research Grants |