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Passini, Jr., Renato
[1]
;
Cecatti, Jose G.
[1, 2]
;
Lajos, Giuliane J.
[1]
;
Tedesco, Ricardo P.
[1, 3]
;
Nomura, Marcelo L.
[1]
;
Dias, Tabata Z.
[1]
;
Haddad, Samira M.
[1]
;
Rehder, Patricia M.
[1]
;
Pacagnella, Rodolfo C.
[1]
;
Costa, Maria L.
[1]
;
Sousa, Maria H.
[2]
;
Preter, Brazilian Multicentre Study
Número total de Autores: 12
|
| Afiliação do(s) autor(es): | [1] Univ Estadual Campinas, Sch Med Sci, Dept Obstet & Gynaecol, Campinas, SP - Brazil
[2] Ctr Studies Reprod Hlth Campinas Cemicamp, Campinas, SP - Brazil
[3] Jundiai Sch Med, Jundiai - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | PLoS One; v. 9, n. 10 OCT 9 2014. |
| Citações Web of Science: | 27 |
| Resumo | |
Background: Preterm birth rate is increasing and is currently a worldwide concern. The purpose of this study was to estimate the prevalence of preterm birth in a sample of health facilities in Brazil and to identify the main risk factors associated with spontaneous preterm births. Methods and Findings: This was a multicentre cross sectional study on preterm births in 20 referral obstetric hospitals with a case-control component to identify factors associated with spontaneous preterm birth. Surveillance was implemented at all centres to identify preterm births. For eligible consenting women, data were collected through a post-delivery questionnaire completed with information from all mother-newborn medical records until death or discharge or at a maximum of 60 days post-delivery, whichever came first. The risk of spontaneous preterm birth was estimated with OR and 95%CI for several predictors. A non-conditional logistic regression analysis was then performed to identify independently associated factors. The overall prevalence of preterm birth was 12.3%. Among them, 64.6% were spontaneous and 35.4% therapeutic. In the case-control component, 2,682 spontaneous preterm births were compared to a sample of 1,146 term births. Multivariate analyses identified the following as risk factors for spontaneous preterm birth among women with at least one previous birth: a previous preterm birth (ORadj = 3.19, 2.30-4.43), multiple pregnancy (ORadj = 29.06, 8.43-100.2), cervical insufficiency (ORadj = 2.93, 1.07-8.05), foetal malformation (ORadj = 2.63, 1.43-4.85), polyhydramnios (ORadj = 2.30, 1.17-4.54), vaginal bleeding (ORadj = 2.16, 1.50-3.11), and previous abortion (ORadj = 1.39, 1.08-1.78). High BMI (ORadj = 0.94, 0.91-0.97) and weight gain during gestation (ORadj = 0.92, 0.89-0.95) were found to be protective factors. Conclusions: The preterm birth rate in these health facilities in Brazil is high and spontaneous preterm births account for two thirds of them. A better understanding of the factors associated with spontaneous preterm birth is of utmost importance for planning effective measures to reduce the burden of its increasing rates. (AU) | |
| Processo FAPESP: | 09/53245-5 - Estudo multicêntrico sobre a prematuridade no Brasil |
| Beneficiário: | José Guilherme Cecatti |
| Modalidade de apoio: | Auxílio à Pesquisa - Pesquisa em Políticas Públicas para o SUS |