Effects of Low-Level Laser Therapy on Skeletal Muscle Repair A Systematic Review

Autor(es)

Alves, Agnelo Neves ^[1] ; Santos Fernandes, Kristianne Porta ^{[1, 2]} ; Deana, Alessandro Melo ^[2] ; Bussadori, Sandra Kalil ^[1] ; Mesquita-Ferrari, Raquel Agnelli ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Nove Julho, Postgrad Program Rehabil Sci, BR-01504001 Sao Paulo - Brazil

^[2] Univ Nove Julho, Postgrad Program Biophoton Appl Hlth Sci, BR-01504001 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION; v. 93, n. 12, p. 1073-1085, DEC 2014.
• Citações Web of Science: 33

Resumo

A review of the literature was performed to demonstrate the most current applicability of low-level laser therapy (LLLT) for the treatment of skeletal muscle injuries, addressing different lasers, irradiation parameters, and treatment results in animal models. Searches were performed in the PubMed/MEDLINE, SCOPUS, and SPIE Digital Library databases for studies published from January 2006 to August 2013 on the use of LLLT for the repair of skeletal muscle in any animal model. All selected articles were critically appraised by two independent raters. Seventeen of the 36 original articles on LLLT and muscle injuries met the inclusion criteria and were critically evaluated. The main effects of LLLT were a reduction in the inflammatory process, the modulation of growth factors and myogenic regulatory factors, and increased angiogenesis. The studies analyzed demonstrate the positive effects of LLLT on the muscle repair process, which are dependent on irradiation and treatment parameters. The findings suggest that LLLT is an excellent therapeutic resource for the treatment of skeletal muscle injuries in the short-term. (AU)

• Processo FAPESP: 11/17638-2 - Efeito do laser em baixa intensidade na expressão de fatores regulatórios miogênicos e atividade de metaloprotease de matriz 2 durante regeneração do músculo esquelético de rato após criolesão
• Beneficiário: Raquel Agnelli Mesquita Ferrari
• Modalidade de apoio: Auxílio à Pesquisa - Regular