Highly Sensitive Electrochemical Sensor for Determination of Vitamin D in Mixtures of Water-Ethanol

Autor(es)

Cincotto, Fernando H. ^[1] ; Canevari, Thiago C. ^[1] ; Machado, Sergio A. S. ^[1]

Afiliação do(s) autor(es)

^[1] State Univ Sao Paulo, Inst Chem, BR-13560970 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Electroanalysis; v. 26, n. 12, p. 2783-2788, DEC 2014.
• Citações Web of Science: 5

Resumo

This paper describes the electrochemical determination of vitamin D-2 (ergocalciferol) and D-3 (cholecalciferol) in mixed organic/water solvent, using a glassy carbon electrode (GCE). The mixing ratio of organic/water solvent has an important influence on the electrocatalytic response of D vitamins on the surface of the glassy carbon electrode. Well-defined peaks for Vitamin D-2 and D-3 were observed in a 40% ethanol/60% water solution with lithium perchlorate as the support electrolyte. This study demonstrated that the glassy carbon electrode is highly sensitive for the determination of vitamin D-2 and D-3, with a limit of detection of 0.13 and 0.118 mu molL(-1), respectively. No significant interference was seen for vitamins A, E and K in the detection of vitamin D. (AU)

• Processo FAPESP: 12/18339-1 - Detecção dos interferentes endócrinos testosterona e estradiol em amostras ambientais empregando eletrodos modificados com grafeno, nanopartículas de ouro e quantum dots.
• Beneficiário: Fernando Henrique Cincotto
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 11/23047-7 - Desenvolvimento de biosensor eletroquímico utilizando sílica mesoporosa contendo nanotubos de carbono obtida pelo processo sol-gel. Determinação eletroquímica de pesticidas
• Beneficiário: Thiago da Cruz Canevari
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado