Antimicrobial photodynamic therapy associated to nonsurgical periodontal treatment in smokers: Microbiological results

Autor(es)

Queiroz, Adriana C. ^[1] ; Suaid, Flavia Adelino ^[2] ; de Andrade, Patricia Freitas ^[2] ; Novaes, Jr., Arthur B. ^[2] ; Taba, Jr., Mario ^[2] ; Palioto, Daniela B. ^[2] ; Grisi, Marcio F. M. ^[2] ; Souza, Sergio L. S. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Fed Amazonas, Sch Dent, BR-69025050 Manaus, Amazonas - Brazil

^[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Bucomaxillofacial Surg & Traumatol & Periodo, BR-14040904 Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY; v. 141, p. 170-175, DEC 2014.
• Citações Web of Science: 9

Resumo

Background: Studies suggest that smokers present more or greater numbers of potential periodontal pathogens than non-smokers. The aim of this study was to investigate the microbiologic effects of adjunctive aPDT on nonsurgical periodontal treatment in smokers with chronic periodontitis (CP). Methods: Twenty smokers with CP had two contralateral teeth randomly assigned in a split-mouth design to receive SRP (CG) or SRP + a single episode of aPDT (TG), with a diode laser and a phenothiazine photosensitizer. Levels of 40 subgingival species were measured using checkerboard DNA-DNA hybridization at baseline and 1, 4 and 12 weeks after periodontal treatment. Results: All 40 bacterial species evaluated were detected in different levels at baseline, with no statistic significant differences between groups. After periodontal treatment, the levels of some bacterial species decreased, while some other species presented an increase. Despite this variation, the statistical analysis was not able to identify significant differences neither at intragroup nor at intergroup comparisons. Conclusion: Periodontal treatment with SRP or SRP + aPDT was not able to reduce levels of 40 subgingival species in smokers with CP. These outcomes indicate that smoking impairs periodontal healing after nonsurgical treatment even associated with aPDT. (C) 2014 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 09/15845-0 - Avaliação do efeito adjunto da terapia fotodinâmica aos procedimentos de raspagem e alisamento radicular em pacientes fumantes. Estudo clínico controlado e randomizado.
• Beneficiário: Sérgio Luís Scombatti de Souza
• Modalidade de apoio: Auxílio à Pesquisa - Regular