Renal perfusion evaluation by alternating current biosusceptometry of magnetic nanoparticles

Autor(es)

Quini, Caio C. ^[1] ; Matos, Juliana F. ^[1] ; Prospero, Andre G. ^[1] ; Calabresi, Marcos Felipe F. ^[1] ; Zufelato, Nicholas ^[2] ; Bakuzis, Andris F. ^[2] ; Baffa, Oswaldo ^[3] ; Miranda, Jose Ricardo A. ^[1]

Afiliação do(s) autor(es)

^[1] UNESP, Inst Biociencias, Dept Fis & Biofis, Botucatu, SP - Brazil

^[2] Univ Fed Goias, Inst Fis, Goiania, Go - Brazil

^[3] Univ Sao Paulo, FFCLRP, Dept Fis, Ribeirao Preto, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Magnetism and Magnetic Materials; v. 380, p. 2-6, APR 15 2015.
• Citações Web of Science: 6

Resumo

Alternating current susceptometry, a simple and affordable technique, was employed to study the sensitivity of this approach to assess rat kidney perfusion by the injection of 200 mu L of magnetic nanoparticles with a concentration of 23 mg/mL in the femoral vein and the measurement of the signal above the kidney. The instrument was able to detect the signal and the transit time of the first and second pass were measured in five animals with average values of 13.6 +/- 4.3 s and 20.6 +/- 7.1 s. (C) 2014 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 11/18696-6 - Novas aplicações da BAC empregando nano partículas magnéticas
• Beneficiário: Caio César Quini
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 10/07639-9 - Motilidade gastrintestinal: investigações clínicas, fisiopatológicas e biofarmacêuticas
• Beneficiário: Ricardo Brandt de Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Temático