Isolation and Characterization of Mayaro Virus from a Human in Acre, Brazil

Autor(es):Mostrar menos -

Terzian, Ana Carolina B. ^[1] ; Auguste, Albert J. ^[2] ; Vedovello, Danila ^[1] ; Ferreira, Marcelo U. ^[3] ; da Silva-Nunes, Monica ^[3] ; Speranca, Marcia A. ^[4] ; Suzuki, Rodrigo B. ^[4] ; Juncansen, Camila ^[4] ; Araujo, Jr., Joao P. ^[5] ; Weaver, Scott C. ^[2] ; Nogueira, Mauricio L. ^[1]

Afiliação do(s) autor(es)

^[1] Fac Med Sao Jose do Rio Preto, Sao Jose Do Rio Preto, SP - Brazil

^[2] Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 - USA

^[3] Univ Sao Paulo, Inst Ciencias Biol, Sao Paulo - Brazil

^[4] Univ Fed ABC, Santo Andre, SP - Brazil

^[5] Univ Estadual Paulista, Botucatu, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: American Journal of Tropical Medicine and Hygiene; v. 92, n. 2, p. 401-404, FEB 2015.
• Citações Web of Science: 16

Resumo

Mayaro virus (MAYV) is widely distributed throughout South America and is the etiologic agent of Mayaro fever, an acute febrile illness often presenting with arthralgic manifestations. The true incidence of MAYV infection is likely grossly underestimated because the symptomatic presentation is very similar to that of dengue fever and other acute febrile tropical diseases. We report the complete genome sequence of a MAYV isolate detected from an Acrelandia patient presenting with fever, chills, and sweating, but with no arthralgia. Results show that this isolate belongs to genotype D and is closely related to Bolivian strains. Our results suggest that the Acre/Mayaro strain is closely related to the progenitor of these Bolivian strains that were isolated between 2002 and 2006. (AU)

• Processo FAPESP: 12/11733-6 - Caracterização biológica e molecular dos isolados de dengue, sorotipo 1 e 2, em São José do Rio Preto, SP, detectados nas temporadas de 2006 a 2013
• Beneficiário: Maurício Lacerda Nogueira
• Modalidade de apoio: Auxílio à Pesquisa - Regular