Development of an electroanalytical method for the quantification of aminopyrine in seized cocaine samples

Autor(es)

de Araujo, William R. ^[1] ; Maldaner, Adriano O. ^[2] ; Costa, Jose L. ^[3] ; Paixao, Thiago R. L. C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim, BR-05508900 Sao Paulo, SP - Brazil

^[2] Brazilian Fed Police, Natl Inst Criminalist, BR-70610200 Brasilia, DF - Brazil

^[3] Criminalist Inst Sao Paulo, Forens Toxicol & Chem Lab, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Microchemical Journal; v. 121, p. 213-218, JUL 2015.
• Citações Web of Science: 7

Resumo

We report the development of a simple and accurate analytical method to detect aminopyrine in seized cocaine samples using a platinum electrode. The quantification of aminopyrine was performed using square wave voltammetry (SWV), where the peak current response was found to increase linearly with aminopyrine concentration over the range 100-1000 mu mol L-1. The repeatability of the electrode response was determined to be 2.4% (n = 15), and the detection limit of the proposed method was estimated to be 22 mu mol L-1 (3 sigma/slope). The accuracy of the proposed method was evaluated comparing the measured aminopyrine concentration in seized cocaine sample to the value obtained by gas chromatography coupled to flame ionization detector (GC-FID). An addition and recovery protocol in seized cocaine samples was also performed. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 12/12106-5 - Utilização de medidas eletroquímicas, colorimétricas e de massa para discriminação de amostras de interesse forense e alimentício utilizando dispositivos inteligentes (línguas e narizes eletrônicos)
• Beneficiário: Thiago Regis Longo Cesar da Paixão
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 11/19903-5 - Desenvolvimento de métodos eletroanalíticos para detecção/discriminação de drogas de abuso, seus adulterantes e explosivos em amostras de interesse forense
• Beneficiário: William Reis de Araujo
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto