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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Development of an electroanalytical method for the quantification of aminopyrine in seized cocaine samples

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Author(s):
de Araujo, William R. [1] ; Maldaner, Adriano O. [2] ; Costa, Jose L. [3] ; Paixao, Thiago R. L. C. [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Inst Quim, BR-05508900 Sao Paulo, SP - Brazil
[2] Brazilian Fed Police, Natl Inst Criminalist, BR-70610200 Brasilia, DF - Brazil
[3] Criminalist Inst Sao Paulo, Forens Toxicol & Chem Lab, Sao Paulo, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Microchemical Journal; v. 121, p. 213-218, JUL 2015.
Web of Science Citations: 7
Abstract

We report the development of a simple and accurate analytical method to detect aminopyrine in seized cocaine samples using a platinum electrode. The quantification of aminopyrine was performed using square wave voltammetry (SWV), where the peak current response was found to increase linearly with aminopyrine concentration over the range 100-1000 mu mol L-1. The repeatability of the electrode response was determined to be 2.4% (n = 15), and the detection limit of the proposed method was estimated to be 22 mu mol L-1 (3 sigma/slope). The accuracy of the proposed method was evaluated comparing the measured aminopyrine concentration in seized cocaine sample to the value obtained by gas chromatography coupled to flame ionization detector (GC-FID). An addition and recovery protocol in seized cocaine samples was also performed. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 12/12106-5 - Development of intelligent devices (electronic noses and tongues) using electrochemical, colorimetric and mass measurements aiming to the discrimination of forensic and food samples
Grantee:Thiago Regis Longo Cesar da Paixão
Support Opportunities: Regular Research Grants
FAPESP's process: 11/19903-5 - Development of electroanalytical methods for detection/discrimination of drugs of abuse, its adulterants and explosives in forensic samples
Grantee:William Reis de Araujo
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)