Histologic and Histometric Analysis of Bone Repair at the Site of Mandibular Body Osteotomy and at the Bone-Screw Interface After Using a Biodegradable 2.0-mm Internal Fixation System

Autor(es)

Sverzut, Cassio Edvard ^[1] ; de Matos, Fernando Pando ^[1] ; Trivellato, Alexandre Elias ^[1] ; Kato, Rogerio Bentes ^[1] ; Sverzut, Alexander Tadeu ^[1] ; Taba Junior, Mario ^[1] ; de Rezende Duek, Eliana Aparecida ^[2] ; de Oliveira, Paulo Tambasco ^[3]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Oral & Maxillofacial Surg & Periodontol, BR-14040904 Sao Paulo - Brazil

^[2] Pontif Catholic Univ Sao Paulo, Sch Med & Hlth Sci, Dept Physiol Sci, Sorocaba - Brazil

^[3] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Morphol Physiol & Basic Pathol, BR-14040904 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF CRANIOFACIAL SURGERY; v. 26, n. 4, p. 1214-1219, JUN 2015.
• Citações Web of Science: 0

Resumo

The aim of the study was to evaluate histologically and histometrically the bone repair at the mandibular body osteotomy and at the bone-screw interface after using a biodegradable 2.0-mm internal fixation system. Six dogs were subjected to an osteotomy in the mandibular body, which was stabilized by applying a fixation device manufactured with poly-L-DL-lactic acid (70: 30). The dogs were euthanized at 2 and 18 weeks. Each screw was sectioned along its long axis, and the osteotomy sites were divided into 3 parts: the upper part was labeled the tension third (TT); the lower part, compression third (CT); and the part between the TT and CT, intermediary third (IT). Histologic analysis showed areas of direct contact between the screw surface and the parent lamellar bone at 2 weeks. At 18 weeks, 3 microscopically distinct layers at the bone-screw interface were noted. At the osteotomy sites, union between the bone fragments was observed at 18 weeks. Statistically significant differences in the newly formed bone among TT, IT, and CT (P = 0.019) were observed. In conclusion, the biomechanical environment created by the biodegradable IF system used in this study facilitated bone repair at the osteotomy site. (AU)

• Processo FAPESP: 07/00892-8 - Análise histológica e histomorfométrica da interface entre tecido ósseo e parafusos metálicos e absorvíveis do sistema 2,0 mm: estudo em cães utilizando fixação interna rígida
• Beneficiário: Cassio Edvard Sverzut
• Modalidade de apoio: Auxílio à Pesquisa - Regular