Effectiveness of a Toothpaste with Low Fluoride Content Combined with Trimetaphosphate on Dental Biofilm and Enamel Demineralization in situ

Autor(es)

Takeshita, Eliana M. ^[1] ; Danelon, Marcelle ^[1] ; Castro, Luciene P. ^[1] ; Sassaki, Kikue T. ^[1] ; Delbem, Alberto C. B. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, UNESP, Aracatuba Dent Sch, BR-16015050 Aracatuba, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Caries Research; v. 49, n. 4, p. 394-400, 2015.
• Citações Web of Science: 12

Resumo

Objective: The aim of the present study was to evaluate in situ whether a toothpaste with low fluoride associated with sodium trimetaphosphate (TMP) would provide similar effect to that of a 1,100 ppm F toothpaste. Design: This crossover double-blind study consisted of 4 phases (14 days each), during which 10 volunteers wore oral appliances containing 4 enamel bovine blocks. The cariogenic challenge was performed by the application of a 20% sucrose solution (6x/day). The toothpaste treatments (2x/day) were: placebo, 500 ppm F, 500 ppm F plus 1% TMP, and 1,100 ppm F. At the end, enamel mineral loss and biofilm composition were analyzed. Results: The toothpaste with 500 ppm F plus 1% TMP showed the lowest mineral loss (p < 0.05). Regarding the fluoride and calcium concentrations in the enamel and in the biofilm, there were no significant differences between 500 ppm F plus 1% TMP, and 1,100 ppm F toothpastes (p > 0.569), but they were significantly different when compared to toothpaste with 500 ppm F (p < 0.050). Conclusion: The addition of 1% TMP to a low-fluoride toothpaste reduces enamel demineralization in situ similar to a 1,100 ppm F toothpaste. (C) 2015 S. Karger AG, Basel (AU)

• Processo FAPESP: 07/03660-0 - Avaliação in situ da ação anticariogênica de dentifrícios com baixa concentração de fluoreto suplementados com fosfato
• Beneficiário: Alberto Carlos Botazzo Delbem
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 07/03254-2 - Avaliação in situ da ação anticariogênica de dentifrício de baixa concentração de fluoreto e suplementado com fosfato
• Beneficiário: Eliana Mitsue Takeshita
• Modalidade de apoio: Bolsas no Brasil - Doutorado