Nonvisual Opsins and the Regulation of Peripheral Clocks by Light and Hormones

Autor(es)

Poletini, Maristela O. ^{[1, 2]} ; Ramos, Bruno C. ^[2] ; Moraes, Maria Nathalia ^[2] ; Castrucci, Ana Maria L. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Fed Minas Gerais, Inst Biol Sci, Dept Physiol & Biophys, Belo Horizonte, MG - Brazil

^[2] Univ Sao Paulo, Inst Biosci, Dept Physiol, Sao Paulo - Brazil

• Tipo de documento: Artigo de Revisão
• Fonte: Photochemistry and Photobiology; v. 91, n. 5, p. 1046-1055, SEP-OCT 2015.
• Citações Web of Science: 3

Resumo

The molecular clock machinery is conserved throughout evolution. However, how environmental cues are perceived has evolved in such a way that peripheral clocks in mammals require a variety of signals, including hormones. On the other hand, in nonmammalian cells able to directly detect light, light seems to play a major role in the synchronization of the clock. The interaction between perception of circadian light by nonvisual opsins and hormones will be discussed under the perspective of clock synchronization at the molecular level. (AU)

• Processo FAPESP: 12/50214-4 - Mecanismos de ajuste do relógio por luz e temperatura: aspectos filogenéticos
• Beneficiário: Ana Maria de Lauro Castrucci
• Modalidade de apoio: Auxílio à Pesquisa - Temático