Temporal changes in calcium-binding proteins in the medial geniculate nucleus of the monkey Sapajus apella

Autor(es)

Campos, Leila M. G. ^{[1, 2]} ; Osorio, Elaine C. ^[1] ; da Silva Santos, Graziela Ligia ^[1] ; Nogueira, Maria Ines ^[3] ; Cruz-Rizzolo, Roelf J. ^[4] ; Pinato, Luciana ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ, Dept Speech Language & Hearing Therapy, Marilia, SP - Brazil

^[2] Univ Marilia, Sch Med, Marilia, SP - Brazil

^[3] Univ Sao Paulo, Inst Biomed Sci, Dept Anat, BR-05508 Sao Paulo, SP - Brazil

^[4] Sao Paulo State Univ, Dept Basic Sci, Aracatuba, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Chemical Neuroanatomy; v. 68, p. 45-54, OCT 2015.
• Citações Web of Science: 2

Resumo

The subdivisions of the medial geniculate complex can be distinguished based on the immunostaining of calcium-binding proteins and by the properties of the neurons within each subdivision. The possibility of changes in neurochemistry in this and other central auditory areas are important aspects to understand the basis that contributing to functional variations determined by environmental cycles or the animal's cycles of activity and rest. This study investigated, for the first time, day/night differences in the amounts of parvalbumin-, calretinin- and calbindin-containing neurons in the thalamic auditory center of a nonhuman primate, Sapajus apella. The immunoreactivity of the PV-IR, CB-IR and CR-IR neurons demonstrated different distribution patterns among the subdivisions of the medial geniculate. Moreover, a high number of CB- and CR-IR neurons were found during day, whereas PV-IR was predominant at night. We conclude that in addition to the chemical heterogeneity of the medial geniculate nucleus with respect to the expression of calcium-binding proteins, expression also varied relative to periods of light and darkness, which may be important for a possible functional adaptation of central auditory areas to environmental changes and thus ensure the survival and development of several related functions. (C) 2015 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 11/51495-4 - Produção de melatonina por células do sistema nervoso central em condições de injúria
• Beneficiário: Luciana Pinato
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores