Ellipsoidal Relaxation of Deformed Vesicles

Autor(es)

Yu, Miao ^[1] ; Lira, Rafael B. ^{[2, 3]} ; Riske, Karin A. ^[2] ; Dimova, Rumiana ^[3] ; Lin, Hao ^[1]

Afiliação do(s) autor(es)

^[1] Rutgers State Univ, Dept Mech & Aerosp Engn, Piscataway, NJ 08854 - USA

^[2] Univ Fed Sao Paulo, Dept Biofis, BR-04044020 Sao Paulo - Brazil

^[3] Max Planck Inst Colloids & Interfaces, Dept Theory & Bio Syst, D-14424 Potsdam - Germany

• Tipo de documento: Artigo Científico
• Fonte: Physical Review Letters; v. 115, n. 12 SEP 18 2015.
• Citações Web of Science: 14

Resumo

Theoretical analysis and experimental quantification on the ellipsoidal relaxation of vesicles are presented. The current work reveals the simplicity and universal aspects of this process. The Helfrich formula is shown to apply to the dynamic relaxation of moderate-to-high tension membranes, and a closed-form solution is derived which predicts the vesicle aspect ratio as a function of time. Scattered data are unified by a time scale, which leads to a similarity behavior, governed by a distinctive solution for each vesicle type. Two separate regimes in the relaxation are identified, namely, the ``entropic{''} and the ``constant-tension{''} regimes. The bending rigidity and the initial membrane tension can be simultaneously extracted from the data analysis, posing the current approach as an effective means for the mechanical analysis of biomembranes. (AU)

• Processo FAPESP: 13/07246-5 - Eletroporação e fusão de vesículas eletricamente carregadas
• Beneficiário: Rafael Bezerra de Lira
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado