Recolonization of Mutans Streptococci after Application of Chlorhexidine Gel

Autor(es)

Glauber Campos Vale ^[1] ; Altair Antoninha Del Bel Cury ^[2] ; Rodrigo Alex Arthur ^[3] ; Jaime Aparecido Cury ^[4] ; Cínthia Pereira Machado Tabchoury ^[5]

Afiliação do(s) autor(es)

^[1] UFPI - Federal University of Piaui - Brasil

^[2] UNICAMP - University of Campinas. Piracicaba Dental School - Brasil

^[3] UFRS - Federal University of Rio Grande do Sul - Brasil

^[4] UNICAMP - University of Campinas. Piracicaba Dental School - Brasil

^[5] UNICAMP - University of Campinas. Piracicaba Dental School - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Brazilian Dental Journal; v. 25, n. 6, p. 485-488, 2014-12-00.

Resumo

Streptococcus mutans is specifically suppressed by intensive treatment with chlorhexidine gel, but the time for recolonization and the effect on other oral bacteria are not totally clear. In this study, recolonization of mutans streptococci was evaluated in nine healthy adult volunteers, who were highly colonized with this microorganism. Stimulated saliva was collected before (baseline) and at 1, 7, 14, 21 and 28 days after application of 1% chlorhexidine gel on volunteers' teeth for two consecutive days. On each day, the gel was applied using disposable trays for 3 x 5 min with intervals of 5 min between each application. Saliva was plated on blood agar to determine total microorganisms (TM); on mitis salivarius agar to determine total streptococci (TS) and on mitis salivarius agar plus bacitracin to determine mutans streptococci (MS). Chlorhexidine was capable of reducing the counts of MS and the proportion of MS with regard to total microorganisms (%MS/TM) (p<0.05), but these values did not differ statistically from baseline (p>0.05) after 14 days for MS and 21 days for %MS/TM. The counts of TM and TS and the proportion of MS to total streptococci did not differ statistically from baseline (p>0.05) after chlorhexidine treatment. The results suggest that the effect of chlorhexidine gel treatment on suppression of mutans streptococci is limited to less than a month in highly colonized individuals. (AU)

• Processo FAPESP: 05/03090-4 - Influência do flúor na acidogenicidade, concentração de polissacarídeos e diversidade genotípica de estreptococos do grupo mutans no biofilme dental detectados por AP-PCR: estudo in situ
• Beneficiário: Gláuber Campos Vale
• Modalidade de apoio: Bolsas no Brasil - Doutorado