Textile dyes induce toxicity on zebrafish early life stages

Autor(es)

Rodrigues de Oliveira, Gisele Augusto ^{[1, 2]} ; de Lapuente, Joaquin ^[3] ; Teixido, Elisabet ^[1] ; Porredon, Constanca ^[3] ; Borras, Miquel ^[3] ; de Oliveira, Danielle Palma ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto, Dept Clin Toxicol & Bromatol Anal, FCFRP USP, BR-14049 Ribeirao Preto, SP - Brazil

^[2] Univ Fed Goias, Fac Pharm, Toxicol Lab, FF UFG, Goiania, Go - Brazil

^[3] UTOX PCB, Unit Expt Toxicol & Ecotoxicol, Barcelona - Spain

• Tipo de documento: Artigo Científico
• Fonte: Environmental Toxicology and Chemistry; v. 35, n. 2, p. 429-434, FEB 2016.
• Citações Web of Science: 18

Resumo

Textile manufacturing is one of the most polluting industrial sectors because of the release of potentially toxic compounds, such as synthetic dyes, into the environment. Depending on the class of the dyes, their loss in wastewaters can range from 2% to 50% of the original dye concentration. Consequently, uncontrolled use of such dyes can negatively affect human health and the ecological balance. The present study assessed the toxicity of the textile dyes Direct Black 38 (DB38), Reactive Blue 15 (RB15), Reactive Orange 16 (RO16), and Vat Green 3 (VG3) using zebrafish (Danio rerio) embryos for 144h postfertilization (hpf). At the tested conditions, none of the dyes caused significant mortality. The highest RO16 dose significantly delayed or inhibited the ability of zebrafish embryos to hatch from the chorion after 96 hpf. From 120 hpf to 144 hpf, all the dyes impaired the gas bladder inflation of zebrafish larvae, DB38 also induced curved tail, and VG3 led to yolk sac edema in zebrafish larvae. Based on these data, DB38, RB15, RO16, and VG3 can induce malformations during embryonic and larval development of zebrafish. Therefore, it is essential to remove these compounds from wastewater or reduce their concentrations to safe levels before discharging textile industry effluents into the aquatic environment. Environ Toxicol Chem 2016;35:429-434. (c) 2015 SETAC (AU)

• Processo FAPESP: 13/01509-4 - Avaliação dos efeitos letais, sub-letais, teratogênicos e genotóxicos de corantes têxteis sobre o desenvolvimento êmbrio-larval de zebrafish (Danio rerio)
• Beneficiário: Danielle Palma de Oliveira
• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/01735-4 - Avaliação dos efeitos letais, sub-letais, teratogênicos e genotóxicos de corantes têxteis sobre o desenvolvimento embrio-larval de zebrafish (Danio rerio)
• Beneficiário: Gisele Augusto Rodrigues de Oliveira
• Linha de fomento: Bolsas no Brasil - Pós-Doutorado