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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Onset of hypertension during pregnancy is associated with long-term worse blood pressure control and adverse cardiac remodeling

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Autor(es):
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Mesquita, Roberto F. [1] ; Reis, Muriel [1] ; Beppler, Ana Paula [1] ; Bellinazzi, Vera Regina [1] ; Mattos, Sandra S. [2] ; Lima-Filho, Jose L. [2] ; Cipolli, Jose A. [1] ; Coelho-Filho, Otavio R. [1] ; Pio-Magalhaes, Jose A. [1] ; Sposito, Andrei C. [1] ; Matos-Souza, Jose R. [1] ; Nadruz, Jr., Wilson [1, 2]
Número total de Autores: 12
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Dept Internal Med, Campinas, SP - Brazil
[2] Univ Fed Pernambuco, Lab Immunopathol Keizo Asami, Recife, PE - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION; v. 8, n. 11, p. 827-831, NOV 2014.
Citações Web of Science: 0
Resumo

Up to 20% of women with hypertensive pregnancy disorders might persist with chronic hypertension. This study compared clinical and echocardiographic features between women whose hypertension began as hypertensive pregnancy disorders (PH group) and women whose diagnosis of hypertension did not occur during pregnancy (NPH group). Fifty PH and 100 NPH women were cross-sectionally evaluated by clinical, laboratory, and echocardiography analysis, and the groups were matched by duration of hypertension. PH exhibited lower age (46.6 +/- 1.4 vs. 65.3 +/- 1.1 years; P < .001), but higher systolic (159.8 +/- 3.9 vs. 148.0 +/- 2.5 mm Hg; P = .009) and diastolic (97.1 +/- 2.4 vs. 80.9 +/- 1.3 mm Hg; P < .001) blood pressure than NPH, although used more antihypertensive classes (3.4 +/- 0.2 vs. 2.6 +/- 0.1; P < .001). Furthermore, PH showed higher left ventricular wall thickness and increased prevalence of concentric hypertrophy than NPH after adjusting for age and blood pressure. In conclusion, this study showed that PH may exhibit worse blood pressure control and adverse left ventricular remodeling compared with NPH. (C) 2014 American Society of Hypertension. All rights reserved. (AU)

Processo FAPESP: 10/16252-0 - Mecanismos envolvidos no aumento do risco cardiovascular em portadores de lesão da medula espinhal
Beneficiário:Wilson Nadruz Junior
Linha de fomento: Auxílio à Pesquisa - Regular