Advances in the non-linear optical investigation of lyotropic-like low-density human lipoproteins in the native and oxidised states

Autor(es)

Alves, S. ^[1] ; Figueiredo Neto, A. M. ^[2]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Inst Fis, BR-01498 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: LIQUID CRYSTALS; v. 41, n. 3, p. 465-470, MAR 4 2014.
• Citações Web of Science: 2

Resumo

The Z-Scan optical technique was recently used to measure the non-linear optical response of human lipoproteins, in particular low-density lipoprotein (LDL) particles, regarding their oxidative (atherogenic) state. The higher is the oxidation degree of the LDL particle, the smaller is their non-linear optical response. The main physical process involved in this phenomenon is the increase in the thermal diffusivity of the aqueous LDL solution, as a function of the oxidation degree. The responsible for the heat diffusion across the sample are the hydroperoxides generated by the oxidation. Other human lipoproteins were shown to present non-linear optical responses in the thermal timescale regime. The non-linear optical response of LDL solutions may be used in the development of new tools to quantify the atherogenic particles in the human blood. (AU)

• Processo FAPESP: 08/57685-7 - Instituto Nacional de Ciência e Tecnologia de Fluídos Complexos
• Beneficiário: Antonio Martins Figueiredo Neto
• Modalidade de apoio: Auxílio à Pesquisa - Temático