Construction of an electrochemical sensing platform based on platinum nanoparticles supported on carbon for tetracycline determination

Autor(es)

Kushikawa, Ricardo T. ^[1] ; Silva, Marcelo R. ^[2] ; Angelo, Antonio C. D. ^[2] ; Teixeira, Marcos F. S. ^[3]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sao Carlos Inst Chem, Sao Carlos, SP - Brazil

^[2] Sao Paulo State Univ UNESP, Fac Sci, Bauru, SP - Brazil

^[3] Sao Paulo State Univ UNESP, Fac Sci & Technol, Presidente Prudente, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SENSORS AND ACTUATORS B-CHEMICAL; v. 228, p. 207-213, JUN 2 2016.
• Citações Web of Science: 15

Resumo

In this paper, we report the construction of an electrochemical sensing platform based on platinum nanoparticles supported on carbon (PtNPs/C) for the determination of the antibiotic tetracycline (TTC). Initially, the PtNPs/C was synthesized and characterized by powder X-ray diffraction spectroscopy and transmission electron microscopy. The effect of experimental parameters on the electrochemical behavior of the PtNPs/C coated glassy carbon electrode (PtNPs/C/GCE), including the amount of PtNPs and electroactive area, scan rate and pH, were evaluated. The electrooxidation of TTC on the PtNPs/C/GCE was investigated by cyclic voltammetry and differential pulse voltammetry, with the determination of TTC electrooxidation mechanism. Under optimum experimental conditions, the linear calibration range, detection limit, quantification and sensitivity of the PtNPs/C/GCE were 9.99-44.01 mol L-1, 4.28 mu mol L-1, 14.3 mu mol L-1 and 3.32 pAL mu mol(-1) cm(-2), respectively. Finally, the proposed electrochemical sensing platform was successfully applied to determine low TTC concentrations in urine samples, suggesting its great applicability in clinical analysis and quality control. (C) 2016 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 05/01296-4 - Desenvolvimento de metodologia analítica empregando eletrodos modificados com oxo complexos polinucleares de rutênio encapsulado em zeolita
• Beneficiário: Marcos Fernando de Souza Teixeira
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores