| Texto completo | |
| Autor(es): |
Yanguas, Sara Crespo
[1]
;
Willebrords, Joost
[1]
;
Maes, Michael
[1]
;
da Silva, Tereza Cristina
[2]
;
Alves Pereira, Isabel Veloso
[2]
;
Cogliati, Bruno
[2]
;
Zaidan Dagli, Maria Lucia
[2]
;
Vinken, Mathieu
[1]
Número total de Autores: 8
|
| Afiliação do(s) autor(es): | [1] Vrije Univ Brussel, Fac Med & Pharm, Dept In Vitro Toxicol & Dermatocosmetol, Laarbeeklaan 103, B-1090 Brussels - Belgium
[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Pathol, Av Prof Dr Orlando Marques de Paiva 87, BR-05508900 Sao Paulo - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo de Revisão |
| Fonte: | EXCLI JOURNAL; v. 15, p. 177-186, 2016. |
| Citações Web of Science: | 10 |
| Resumo | |
Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets. (AU) | |
| Processo FAPESP: | 13/50420-6 - Canais de conexina e panexina como alvos terapêuticos e biomarcadores nas doenças hepáticas aguda e crônica |
| Beneficiário: | Mathieu Frederick Alexander Vinken |
| Modalidade de apoio: | Auxílio à Pesquisa - Programa SPEC |