Simple and Sensitive Paper-Based Device Coupling Electrochemical Sample Pretreatment and Colorimetric Detection

Autor(es)

Silva, Thalita G. ^[1] ; de Araujo, William R. ^[1] ; Munoz, Rodrigo A. A. ^[2] ; Richter, Eduardo M. ^[2] ; Santana, Mario H. P. ^[3] ; Coltro, Wendell K. T. ^[4] ; Paixao, Thiago R. L. C. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Quim, BR-05508000 Sao Paulo, SP - Brazil

^[2] Univ Fed Uberlandia, Inst Quim, BR-38400902 Uberlandia, MG - Brazil

^[3] Superintendencia Reg Dept Policia Fed MG, Unidade Tecn Cient, BR-38408680 Uberlandia, MG - Brazil

^[4] Univ Fed Goias, Inst Quim, Campus Samambaia, BR-74690900 Goiania, Go - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Analytical Chemistry; v. 88, n. 10, p. 5145-5151, MAY 17 2016.
• Citações Web of Science: 27

Resumo

We report the development of a simple, portable, low-cost, high-throughput-visual colorimetric paper-based analytical device for the detection of procaine in seized cocaine samples. The interference of most common cutting agents found in cocaine samples was verified, and a novel electrochemical approach was used for sample pretreatment in order to increase the selectivity. Under the optimized experimental conditions, a linear analytical curve was obtained for procaine concentrations ranging from 5 to 40 mu mol L-1 with a detection limit of 0.9 mu mol L-1. The accuracy of the proposed method was evaluated using seized cocaine samples and an addition and recovery protocol. (AU)

• Processo FAPESP: 11/19903-5 - Desenvolvimento de métodos eletroanalíticos para detecção/discriminação de drogas de abuso, seus adulterantes e explosivos em amostras de interesse forense
• Beneficiário: William Reis de Araujo
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto