Se-77 and Te-125 NMR spectroscopy for enantiopurity determination of chalcogen amines

Autor(es)

Oliveira, Samuel S. ; Cunha, Rodrigo L. O. R. ; Silva, Marcio S.

• Tipo de documento: Artigo Científico
• Fonte: Tetrahedron Letters; v. 57, n. 41, p. 4556-4559, OCT 12 2016.
• Citações Web of Science: 5

Resumo

A simple three-component chiral derivatizing protocol for determining the enantiopurity of chalcogen amines by H-1, Se-77 and Te-125 NMR spectroscopy is described. The method involves the formation of a chalcogen-imino-boronate ester complex by the coupling of racemic chalcogen amines, 2-formylphenylboronic acid and optically active (+)-BINOL. The chalcogen primary amines were synthesized by a non active aziridine ring-opening reaction and chalcogen nucleophilic species. (C) 2016 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 14/23362-8 - Uso de técnicas não clássicas de ressonância magnética nuclear no planejamento e discriminação quiral de processos biocatalíticos
• Beneficiário: Márcio Santos da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular