Kinetic Control of Microtubule Morphology Obtained by Assembling Gold Nanoparticles on Living Fungal Biotemplates

Autor(es)

Kubo, Andressa M. ; Gorup, Luiz F. ; Amaral, Luciana S. ; Filho, Edson R. ; Camargo, Emerson R.

• Tipo de documento: Artigo Científico
• Fonte: BIOCONJUGATE CHEMISTRY; v. 27, n. 10, p. 2337-2345, OCT 2016.
• Citações Web of Science: 5

Resumo

Self-assembly of nanoparticles on living biotemplate surfaces is a promising route to fabricate nano- or microstructured materials with high efficiency and efficacy. We used filamentous fungi to fabricate microtubules of gold nanoparticles through a novel approach that consists of isolating the hyphal growth from the nanoparticle media. This improved methodology resulted in better morphological control and faster adsorption kinetics, which reduced the time needed to form homogeneous microtubules and allowed for control of microtubule thickness through successive additions of nanoparticles. Differences in the adsorption rates due to modifications in the chemical identity of colloidal gold nanoparticles indicated the influence of secondary metabolites and growth media in the fungi metabolism, which demonstrated the need to choose not only the fungus biotemplate but also the correct medium to obtain microtubules with superior properties. (AU)

• Processo FAPESP: 15/13958-3 - Biomateriais nanocompósitos a base de hidrogéis termossensíveis
• Beneficiário: Emerson Rodrigues de Camargo
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
• Beneficiário: Elson Longo da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs