Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy

Autor(es)

Zuza, Elizangela P. ; Barroso, Eliane M. ; Fabricio, Mariana ; Carrareto, Ana Luiza V. ; Toledo, Benedicto E. C. ; Pires, Juliana R.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF ORAL SCIENCE; v. 58, n. 3, p. 423-430, SEP 2016.
• Citações Web of Science: 1

Resumo

Periodontal treatment may improve the metabolic control of dyslipidemia. The aim of this study was to evaluate the lipid profile and high-sensitivity C-reactive protein (hs-CRP) levels in obese and non-obese patients undergoing periodontal therapy. Patients with generalized chronic periodontitis were divided into obese (n = 28) and non-obese groups (n = 26). The periodontal parameters (visible plaque index, gingival bleeding index, probing depth, clinical attachment level, and bleeding on probing), anthropometric measurements (body mass index, waist circumference, and body fat), and serum analyses (triglycerides, total cholesterol, high-density lipoprotein, low-density lipoprotein, fasting glucose, glycated hemoglobin, and hs-CRP) were measured at baseline and 90 days after periodontal treatment. The results showed that the obese subjects presented alterations in triglycerides, total cholesterol, low-density lipoprotein, and hs-CRP at baseline when compared with non-obese patients (P < 0.05). Periodontal treatment could improve the periodontal parameters in both groups similarly (P > 0.05). Obese subjects showed a significant decrease in the levels of triglycerides, total cholesterol, low-density lipoprotein, and hs-CRP post-therapy (P < 0.05), while non-obese patients showed improvement only in hs-CRP (P < 0.05). In conclusion, periodontal treatment could improve the periodontal parameters and circulating hs-CRP in obese and non-obese subjects. Lipid profile was modified only in obese patients post-therapy. (AU)

• Processo FAPESP: 10/17614-3 - Efeito do tratamento periodontal sobre o perfil lipídico de pacientes obesos com periodontite crônica.
• Beneficiário: Mariana Fabricio
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica