F-18-FDG uptake by rectal cancer is similar in mucinous and nonmucinous histological subtypes

Autor(es)

dos Anjos, Dalton A. ; Habr-Gama, Angelita ; Vailati, Bruna B. ; Rossi, Cecilia B. ; Coturel, Adelina E. ; Perez, Rodrigo O. ; Sao Juliao, Guilherme P. ; de Sousa, Joao B. ; Buchpiguel, Carlos A.

• Tipo de documento: Artigo Científico
• Fonte: ANNALS OF NUCLEAR MEDICINE; v. 30, n. 8, p. 513-517, OCT 2016.
• Citações Web of Science: 3

Resumo

PET/CT has been considered limited for the evaluation of mucinous colorectal tumors due to low F-18-FDG uptake. The aim of our study was to compare PET/CT variables in mucinous (MC) and nonmucinous (NMC) rectal adenocarcinomas. Consecutive patients with cT2-4N0-2M0 rectal cancer included in a prospective clinical trial were reviewed. PET/CT was performed for primary baseline staging. Visual and quantitative analysis included SUVmax and SUVmean, metabolic tumor volume (MTV) and total lesion glycolysis (TLG). PET/CT parameters were compared according to histological subtypes. Overall, 73 patients were included (18 mucinous and 55 nonmucinous). SUVmax values were similar between MC and NMC (19.7 vs. 16.6; p = 0.5). MTV and TLG values were greater in the MC group (103.9 vs. 54.1; p = 0.007 and 892.5 vs. 358.8; p = 0.020) due to larger tumor volumes of MC. Metabolic parameters at baseline PET/CT for patients with rectal cancer are similar in mucinous and nonmucinous histological subtypes. (AU)

• Processo FAPESP: 07/51069-0 - Estudo do valor da tomografia computadorizada por emissão de pósitrons na avaliação da resposta do adenocarcinoma do reto e radioterapia e quimioterapia neoadjuvante
• Beneficiário: Rodrigo Oliva Perez
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado