Current advances in biological production of propionic acid

Autor(es)

Es, Ismail ; Khaneghah, Amin Mousavi ; Hashemi, Seyed Mohammad Bagher ; Koubaa, Mohamed

• Tipo de documento: Artigo de Revisão
• Fonte: Biotechnology Letters; v. 39, n. 5, p. 635-645, MAY 2017.
• Citações Web of Science: 9

Resumo

Propionic acid and its derivatives are considered ``Generally Recognized As Safe'' food additives and are generally used as an anti-microbial and anti-inflammatory agent, herbicide, and artificial flavor in diverse industrial applications. It is produced via biological pathways using Propionibacterium and some anaerobic bacteria. However, its commercial chemical synthesis from the petroleum-based feedstock is the conventional production process bit results in some environmental issues. Novel biological approaches using microorganisms and renewable biomass have attracted considerable recent attention due to economic advantages as well as great adaptation with the green technology. This review provides a comprehensive overview of important biotechnological aspects of propionic acid production using recent technologies such as employment of co-culture, genetic and metabolic engineering, immobilization technique and efficient bioreactor systems. (AU)

• Processo FAPESP: 15/14468-0 - SISTEMAS MICROFLUÍDICOS PARA A INCORPORAÇÃO DE SMALL INTERFERING RNA (siRNA) EM LIPOSSOMAS CATIÔNICOS E PARA TRANSFECÇÃO IN VITRO DE CÉLULAS DE MAMÍFEROS DESTINADOS À TERAPIA GÊNICA
• Beneficiário: Ismail Es
• Modalidade de apoio: Bolsas no Brasil - Doutorado