| Texto completo | |
| Autor(es): |
Monico-Neto, Marcos
;
Dattilo, Murilo
;
Ribeiro, Daniel Araki
;
Lee, Kil Sun
;
de Mello, Marco Tulio
;
Tufik, Sergio
;
Moreira Antunes, Hanna Karen
Número total de Autores: 7
|
| Tipo de documento: | Artigo Científico |
| Fonte: | GROWTH FACTORS; v. 35, n. 1, p. 12-18, 2017. |
| Citações Web of Science: | 3 |
| Resumo | |
Introduction: The aim was observe the influence of sleep deprivation (SD) and sleep recovery on muscle regeneration process in rats submitted to cryolesion. Methods: Thirty-two Wistar rats were randomly allocated in four groups: control (CTL), SD for 96 h (SD96), control plus sleep recovery period (CTL + R) and SD96h plus 96 h of sleep recovery (SD96 + R). The animals were submitted to muscle injury by cryolesioning, after to SD and sleep recovery. Results: The major outcomes of this study were the reduction of muscular IGF-1 in both legs (injured and uninjured) and a delay in muscle regeneration process of animals submitted to SD compared to animals that slept, with increase connective tissue, inflammatory infiltrate and minor muscle fibers. Conclusions: SD impairs muscle regeneration in rats, moreover reduces muscular IGF-1 and sleep recovery was able to restore it to basal levels, but it was not enough to normalize the muscle regeneration. (AU) | |
| Processo FAPESP: | 13/00152-5 - Efeito do exercício físico resistido no músculo esquelético e cardíaco de ratos Wistar submetidos a privação de sono paradoxal |
| Beneficiário: | Hanna Karen Moreira Antunes |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 09/11056-1 - Efeitos da privação de sono no processo de recuperação muscular |
| Beneficiário: | Murilo Dattilo |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 11/15962-7 - Efeitos do exercício físico resistido nas vias tróficas e atróficas da musculatura esquelética de ratos submetidos à privação de sono paradoxal |
| Beneficiário: | Marcos Mônico Neto |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |
| Processo FAPESP: | 98/14303-3 - Center for Sleep Studies |
| Beneficiário: | Sergio Tufik |
| Modalidade de apoio: | Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs |