Center for Sleep Studies

• Processo: 98/14303-3
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Vigência: 01 de outubro de 2000 - 31 de dezembro de 2012
• Área do conhecimento: Interdisciplinar
• Pesquisador responsável: Sergio Tufik
• Beneficiário: Sergio Tufik
• Instituição Sede: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brasil
• Pesquisadores principais: Deborah Suchecki ; Lia Rita Azeredo Bittencourt ; Luiz Eugenio Araujo de Moraes Mello ; Marco Túlio de Mello ; Roberto Frussa Filho
• Auxílios(s) vinculado(s): 06/61203-2 - Percentile values of visceral obesity to development nonalcoholic fatty liver disease (NAFLD) in obese adolescents, AR.EXT; 06/56350-6 - Robert Pietr Skomro | Royal University Hospital - Canadá, AV.EXT; 03/06654-0 - Effects of sleep deprivation on serotonin transporter and 5-ht2 receptors binding., AR.EXT
• Bolsa(s) vinculada(s): 12/10617-2 - Efeito da Síndrome da Apneia Obstrutiva do Sono de grau leve sobre a qualidade de vida, humor e cognição, estudo caso-controle, BP.IC; 12/07144-5 - Efetividade do "Continuous Positive Airway Pressure" (CPAP) e do Aparelho Intra-Oral (AIO) na Síndrome da Apneia Obstrutiva do Sono de grau leve: estudo randomizado, paralelo, simples cego e controlado., BP.TT; 11/18976-9 - Aspectos genéticos e fisiológicos do perfil oxidativo no sono e envelhecimento bem-sucedido, BP.DD; + mais bolsas vinculadas 10/14768-0 - Efeito da restrição de sono durante a gravidez sobre o comportamento materno em ratas, BP.MS; 10/15110-8 - Sono e morte súbita nas epilepsias: provável base molecular?, BP.PD; 10/05372-5 - Contribuição da corticosterona sobre a evocação de tarefas aversivamente motivadas em animais privados de sono, BP.IC; 10/09087-3 - O papel da prolactina no rebote de sono paradoxal induzido pelo estresse, BP.PD; 09/04240-0 - Efeitos da privação e restrição de sono na integridade da pele: quantificação de colágeno na pele de camundongos hairless, BP.MS; 09/13080-7 - Estratégias de reversão dos efeitos deletérios da privação de sono sobre a memória: o sono de ondas lentas é importante?, BP.MS; 09/12116-8 - Aspectos genéticos e fisiológicos do perfil oxidativo no sono e envelhecimento saudável, BP.MS; 09/18369-5 - Comparação dos efeitos do CPAP e do AIO isoladamente ou associados ao treinamento físico aeróbio na Síndrome da Apnéia Obstrutiva do Sono, BP.TT; 09/17753-6 - PROJETO DE PESQUISA: Validação do Aparelho de registro cardio-respiratório "Stardust"" para diagnóstico da Síndrome da Apnéia Obstrutiva do Sono (SAOS) em voluntarios com idade acima de 65 anos, BP.TT; 09/05518-2 - Avaliação dos aspectos neuropsicológicos, padrão e eficiência do sono em indivíduos expostos a altitude, BP.TT; 09/13881-0 - Efetividade da hidroterapia no padrão de sono em pacientes portadores de fibromialgia, BP.TT; 09/05619-3 - Efeitos da privação do sono em saguis (Callithrix jacchus) no padrão eletroencefalográfico e na liberação basal de serotonina, noradrenalina, dopamina no córtex pré-frontal, hipocampo dorsal, amígdala e núcleo accumbens, BP.PD; 09/01030-5 - Efeito da privação e restrição de sono na função reprodutiva de ratos machos, BP.DR; 09/00465-8 - Caracterização experimental dos efeitos amnésticos imediatos ou tardios promovidos pela privação parcial crônica de sono paradoxal ou total em camundongos: aspectos comportamentais, moleculares e genéticos, BP.PD; 09/02484-0 - Análise eletrofisiológica, hormonal e molecular em ratos submetidos à extinção na tarefa de condicionamento de medo ao contexto, BP.PD; 09/05442-6 - Efetividade da hidroterapia no padrão de sono em pacientes portadores de fibromialgia, BP.TT; 09/01031-1 - Comparação dos efeitos do CPAP e do AIO isoladamente ou associados ao treinamento físico aeróbio na Síndrome da Apnéia Obstrutiva do Sono., BP.PD; 08/08823-8 - Efeitos do zolpidem sobre o aprendizado e a memória de camundongos avaliados no modelo da esquiva discriminativa em labirinto em cruz elevado, BP.MS; 08/50646-6 - Efeitos do exercício físico em um modelo animal de síndrome das pernas inquietas e de movimentos periódicos das pernas, BP.PD; 07/55445-6 - Sono e imunidade: evidências em voluntários saudáveis e em modelo animal de transplante de pele, BP.DD; 06/58105-9 - Busca de possiveis associacoes de polimorfismos do gene aa-nat com os diferentes cronotipos em uma amostragem da populacao brasileira., BP.MS; 06/58275-1 - Efeitos da privação de sono na resposta ao lipopolissacarídeo bacteriano: aspectos comportamentais, neuroquímicos e imunológicos em camundongos, BP.MS; 07/50525-1 - Epidemiologia do sono na cidade de São Paulo - Episono 2007, BP.PD; 07/50534-0 - Caracterização do padrão de sono em modelos animais de epilepsia, BP.DD; 06/58274-5 - Influencia da restricao alimentar no comportamento sexual de ratos machos., BP.MS; 06/58276-8 - Avaliação da densidade do transportador dopaminérgico utilizando [99mtc]-trodat e SPECT após privação de sono, BP.MS; 06/58297-5 - Os efeitos da restrição de sono crônica sobre o desempenho de ratos na tarefa de esquiva inibitória, BP.MS; 06/57158-1 - Estudo do sono como fator prognostico em um modelo experimental de doenca auto imune., BP.PD; 06/58104-2 - Genética epidemiológica do sono: análise da influência de polimorfismos nos genes Reverb alfa e Bmal1 na determinação dos cronotipos matutinos e vespertinos em uma amostra da população brasileira, BP.PD; 06/59345-3 - Desenvolvimento de um sistema de transmissao de sinais polissonograficos por telemetria para pequenos animais., BP.PD; 06/59568-2 - Estratificação de risco cardiovascular em pacientes com síndrome da apnéia obstrutiva do sono (estudo ERA), BP.PD; 06/55968-6 - Análise da arquitetura do sono em modelos animais de parkinsonismo, BP.DR; 06/53796-3 - Relacao do desempenho de ratos em uma tarefa de esquiva inibitoria com o padrao polissonografico., BP.DR; 05/57504-4 - Busca da associacao dos alelos do gene da enzima conversora de angio tensina(eca) em pacientes com a sindrome de apneia obstrutiva do sono., BP.MS; 05/57525-1 - Avaliacao dos disturbios do sono em trabalhadores em turno de revezamento das usinas nucleares brasileiras., BP.MS; 05/57966-8 - Participação do sistema dopaminérgico do sono paradoxal, BP.MS; 05/58077-2 - Busca de associações de polimorfismos nos receptores de hipocretina em fenótipos do sono em voluntários sadios da Cidade de São Paulo, BP.MS; 05/58078-9 - Niveis de hipocretina-1 no liquido cefalorraquidiano de ratos tratados com antidepressivos e em modelo animal de depressao., BP.MS; 04/15837-4 - Caracterizacao molecular do gene relogio per 3 do sagui (callithrix jacchus)., BP.DR; 05/54956-1 - Efeitos da hipóxia neonatal associada ou não a privação de sono em camundongos: possíveis alterações comportamentais relacionadas a relacionadas a esquizofrenia, BP.DR; 05/51993-3 - Análise eletrofisiológica e comportamental do sono em Callithrix jacchus, BP.TT; 05/52045-1 - Avaliação das características homeostáticas e circadianas no déficit de memória de ratos privados de sono, BP.MS; 04/12871-7 - Participacao do acth e corticosterona nas consequencias da privacao de sono paradoxal em ratos., BP.DR; 04/11379-1 - Busca de possíveis associações entre polimorfismos existentes nos genes AA - NAT ("arylalkylamine N - acetyltransferase") e HIOMT (hidroxindol-O-metiltransferase) com a Síndrome de Fase Atrasada do Sono (SFAS), BP.MS; 04/12910-2 - Efeitos da privacao de sono sobre a discinesia orofacial induzida por reserpina: possivel participacao da supersensibilidade dopaminergica, do estresse oxidativo e da transmissao gabaergica., BP.MS; 04/04008-7 - Influência da hipóxia intermitente e privação de sono nos marcadores de estresse oxidativo e fatores de risco cardiovascular em ratos, BP.DR; 04/02213-2 - O estresse na expressão do efeito rebote após a privação de sono, BP.DR; 04/03979-9 - Efeito da privação de sono no ciclo estral de ratas, BP.MS; 03/06297-3 - Avaliacao dos efeitos do exercicio fisico aerobio nos movimentos periodicos de pernas., BP.DR; 03/12989-5 - Desenvolvimento de um modelo de epilepsia do lobo temporal em saguis, BP.DD; 02/12453-5 - Avaliação de receptores GABA-A após a privação de sono paradoxal e o papel do sistema gabaérgico no prejuízo de aquisição da tarefa de esquiva inibitória após a privação do sono paradoxal, BP.MS; 02/05201-0 - Estudo da influência da privação de sono paradoxal sobre o desempenho de ratos em um modelo de atenção visual sustentada, BP.MS; 01/07336-7 - Avaliação funcional comportamental da participação dos dopaminoceptores D1 em fenômenos de plasticidade dopaminérgica induzidos por fatores farmacológicos, fisiológicos e psicológicos, BP.DR; 01/10713-7 - Efeitos da privação de sono paradoxal sobre os déficits de memória promovidos pelo envelhecimento: possível participação do sistema colinérgico e do estresse oxidativo cerebral, BP.PD; 01/11389-9 - Efeitos de manipulacoes precoces na arquitetura do sono basal e em respostas ao estresse em ratos., BP.MS; 01/08063-4 - Estudo comparativo do tratamento clinico da sindrome de apneia-hipopneia obstrutiva do sono pela medicina ocidental e pela acupuntura., BP.DR; 01/07263-0 - Privação de sono e doença auto-imune, BP.DR; 01/08193-5 - Uma metodologia "fuzzy" possibilistica para interpretacao de inferencias inconsistentes em computacao flexivel., BP.PD; 01/04329-0 - Sono e cocaína, BP.DR; 00/13771-5 - Analise do padrao e queixas de sono em motoristas de onibus., BP.MS; 00/15092-8 - Avaliação da incidência de movimentos periódicos das patas durante o sono em ratos com lesão medular, BP.MS; 00/12455-2 - Efeitos atípicos do benzodiazepínico lorazepam sobre a pré-ativação e a percepção visual, BP.PD - menos bolsas vinculadas
• Assunto(s): Fisiologia do sistema nervoso Sono
• Publicação FAPESP: https://media.fapesp.br/bv/uploads/publicacoes/pasta_cepid_21.pdf

Resumo

Sleep loss can induce a variety of serious problems, which have been largely neglected as objects of study. As an example, it is estimated obstructive sleep apnea occurs in 2% of children between the ages of 4 and 7; the resulting sleep loss may lead to significant behavioral and cognitive def including leaning problems in school. In the work place, a significant number of accidents involving shift workers are associated with sleep loss or poor quality sleep. A third area where sleep problems have been largely overlooked refers to traffic accidents. Brazil relies heavily on highway transportation (1.000.000 highway miles) to cover its vest territorial expanse. A common cause of traffic accidents involves drivers falling asleep at the wheel and alterations in motor and reaction time associated with sleepiness. Of the 25.000 deaths in traffic accidents each year in Brazil, 27% are attributed to sleep-related problems. Likewise various types of industrial accidents, many of which involving heavy machinery, have been attributed to insufficient sleep or sleep-related disturbances. A understanding of the causes and mechanisms of normal and pathological sleep could have a significant impact on all of these problems. There is at pr group at UNIFESP working under Prof. Dr. Sergio Tufik's direction that has been active for a number of years in clinical and basic sleep research, teaching patient care. The group seeks to elucidate the functions of sleep, to understand sleep-related pathology and to test new therapeutic approaches for sleep-related disorders. In view of the complexity of the subject, the approach taken is of necessity multidisciplinary. Undergraduate and graduate courses are offered y allow dissemination and discussion of current knowledge concerning the possible functions of sleep, biological rhythms, differences among sleep phases, disorders and therapy, among other topics. Research studies are carried out in humans and rodents. At present, however, this group is limited in its reseal scope and deficient in specific areas, particularly in the integration of clinical and basic findings and in extending these findings to society at large, including general population, students, physicians, and policy makers. To address these limitations, we are proposing the creation of a Center for Sleep Studies that expand and integrate our research activities, and will make it possible 1) to shorten the distance between research findings and clinical applications; 2) to basic research efforts more effectively towards relevant clinical issues; 3) to bridge the gap between research discovery and industrial application, and 4) to effectively disseminate research findings to society at large. Infrastructure Contribution from the parent institution to the Center will include a 1200 physical area for clinical and basic research. In the clinical area 10 beds are already available for polysomnographic assessments, which are essential for diagnosis and therapeutic, follow up, and physical space is available to accommodate 16 additional polysomnography systems. Current staff includes 6 MDs three of whom also have PhDs; 2 nurses specializing in sleep disorders and 20 specialized technicians. In the basic research area the current group includes 3 PhDs and another three with whom we maintain close collaborative ties (at the Federal University of Uberlandia, MG, at the Clarke Institute of Psychiatry, and the Department of Pediatrics at UNIFESP). Both clinical and basic research areas have at present a total of 15 graduate students, in addition to undergraduate students in entry level research programs and trainees. The creation of the Center will make it possible to implement additional collaborative this with researchers from other departments at UNIFESP (Pharmacology and Physiology) and from Claude Bernard University in France. These new partnerships will allow us to expand the multidisciplinary character of our research work and will also generate significant benefits in terms of training and technology transfer. Addition of these new investigators will allow us to increase the number of graduate students to 30 and increase the number of undergraduate trainees. Most importantly, it will provide access to training and teaching by experts in other areas. Our collaborators from abroad will make it possible to e our current techniques in basic research and will facilitate exchange initiatives involving researchers and graduate students. Research Focus the principal focus of our basic research studies have been on the effects of sleep deprivation (SD) on various neurochemical systems, using physiological, behavioral, pharmacologir.al and biochemical techniques. Sleep deprivation research is important in at least three different contexts: 1) SD can be a useful understanding the functions or normal sleep; 2) SD studies in normal animals and humans are critical for understanding mechanisms involved in condition such as insomnia, fibromyalgia, sleep apnea, affective disorders and rhythm disturbances, where sleep loss occurs; 3) SD serves a model for conditions where deprivation may be a primary cause of pathology. It may also result in neural damage. Our basic research effort has reached a stage where further pre clearly necessitates the introduction of refinements in technique in our sleep deprivation studies. The need to invest in molecular biology approaches is apparent and so is the need to expand our efforts into studies of normal sleep processes in rodents. The creation of the Center will make it possible for us to start systematic studies focused on normal sleep, with the introduction of single cell recording, microelectrophoresis and microdialysis. We will establish a new research front in the area of sleep deprivation, including interactions between various drugs and sleep. Substances such as alcohol and amphetamines a abused by individuals that have sleep disturbances but little is known about cause and effect relationships. Our current clinical research group original a survey of sleep complaints in the city of Sao Paulo in 1986. This group's work has focused on the study of mechanisms underlying sleep-related pathological conditions, and treatment strategies for these conditions. Sleep Medicine is an inherently multidisciplinary activity and involves disciplines such as Neurology Psychiatry, Pneumology, Otorhinolaryngology, Pediatrics and Orthodontics. A major focus of the proposed studies in clinical areas is obstructive sleep apt including diagnosis, treatment and cognitive effects in children; another are new approaches to diagnosis and treatment of insomnia and rhythm abnormalities Education and Technology Transfer We plan to offer a number of specific services to society at large, including: Publication of information packages booklets aimed at the scientific community and the general population. Training of elementary and high school teachers. Training of high school teachers students in entry level research programs (scientific initiation programs). Implementation of partnerships with organizations responsible for implement public policy, including work with government agencies to introduce measures and legislation to reduce workplace and traffic accidents related to sleepiness. Graduate courses and specialization courses. Development and possible commercialization of novel devices for diagnostic and treatment of sleep-related, disorders, possibly in partnership with government and industry. Increasing awareness among patients, families and government concerning the importance diagnosis and treatment of sleep disorders. A WEB page in Portuguese aimed at the lay public, MDs and other health care professionals dealing with of sleep hygiene, sleep physiology and sleep pathology. (AU)

Publicações científicas

(242)

(Referências obtidas automaticamente do Web of Science e do SciELO, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores)

MONICO-NETO, MARCOS; DATTILO, MURILO; RIBEIRO, DANIEL ARAKI; LEE, KIL SUN; DE MELLO, MARCO TULIO; TUFIK, SERGIO; MOREIRA ANTUNES, HANNA KAREN. REM sleep deprivation impairs muscle regeneration in rats. GROWTH FACTORS, v. 35, n. 1, p. 12-18, 2017. (13/00152-5, 09/11056-1, 11/15962-7, 98/14303-3)

KISHI, AKIFUMI; VAN DONGEN, HANS P. A.; NATELSON, BENJAMIN H.; BENDER, AMY M.; PALOMBINI, LUCIANA O.; BITTENCOURT, LIA; TUFIK, SERGIO; AYAPPA, INDU; RAPOPORT, DAVID M.. Sleep continuity is positively correlated with sleep duration in laboratory nighttime sleep recordings. PLoS One, v. 12, n. 4, APR 10 2017. (98/14303-3)

GUINDALINI, C.; COLUGNATI, F. A. B.; PELLEGRINO, R.; SANTOS-SILVA, R.; BITTENCOURT, L. R. A.; TUFIK, S.. Influence of genetic ancestry on the risk of obstructive sleep apnoea syndrome. European Respiratory Journal, v. 36, n. 4, p. 834-841, OCT 2010. (98/14303-3)

LUNGATO, LISANDRO; NOGUEIRA-PEDRO, AMANDA; DIAS, CAROLINA CARVALHO; PAREDES-GAMERO, EDGAR JULIAN; TUFIK, SERGIO; D'ALMEIDA, VANIA. Effects of Sleep Deprivation on Mice Bone Marrow and Spleen B Lymphopoiesis. Journal of Cellular Physiology, v. 231, n. 6, p. 1313-1320, JUN 2016. (98/14303-3)

NUNES, RAFAEL ALMEIDA; MAZZOTTI, DIEGO ROBLES; HIROTSU, CAMILA; ANDERSEN, MONICA L.; TUFIK, SERGIO; BITTENCOURT, LIA. The association between caffeine consumption and objective sleep variables is dependent on ADORA2A c.1083T>C genotypes. Sleep Medicine, v. 30, p. 210-215, FEB 2017. (98/14303-3)

ANDERSEN, M. L.; RIBEIRO, D. A.; BERGAMASCHI, C. T.; ALVARENGA, T. A.; SILVA, A.; ZAGER, A.; CAMPOS, R. R.; TUFIK, S.. Distinct effects of acute and chronic sleep loss on DNA damage in rats. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 33, n. 3, p. 562-567, APR 30 2009. (06/58274-5, 07/01228-4, 98/14303-3)

MAZZOTTI, DIEGO ROBLES; GUINDALINI, CAMILA; PELLEGRINO, RENATA; BARRUECO, KARINA FONSECA; SANTOS-SILVA, ROGERIO; AZEREDO BITTENCOURT, LIA RITA; TUFIK, SERGIO. Effects of the Adenosine Deaminase Polymorphism and Caffeine Intake on Sleep Parameters in a Large Population Sample. Sleep, v. 34, n. 3, p. 399-402, MAR 1 2011. (98/14303-3)

ARAUJO, P.; MAZARO-COSTA, R.; TUFIK, S.; ANDERSEN, M. L.. Impact of sex on hyperalgesia induced by sleep loss. Hormones and Behavior, v. 59, n. 1, p. 174-179, JAN 2011. (10/50130-0, 98/14303-3)

HIROTSU, CAMILA; TUFIK, SERGIO; BERGAMASCHI, CASSIA TOLEDO; TENORIO, NEULI MARIA; ARAUJO, PAULA; ANDERSEN, MONICA LEVY. Sleep pattern in an experimental model of chronic kidney disease. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, v. 299, n. 6, p. F1379-F1388, DEC 2010. (98/14303-3, 10/50129-1)

GUINDALINI, CAMILA; MARTINS, RAQUEL CRISTINA; ANDERSEN, MONICA L.; TUFIK, SERGIO. Influence of genotype on dopamine transporter availability in human striatum and sleep architecture. PSYCHIATRY RESEARCH, v. 179, n. 2, p. 238-240, SEP 30 2010. (98/14303-3)

GUINDALINI, CAMILA; LEE, KIL S.; ANDERSEN, MONICA L.; SANTOS-SILVA, ROGERIO; BITTENCOURT, LIA RITA A.; TUFIK, SERGIO. The influence of obstructive sleep apnea on the expression of glycerol-3-phosphate dehydrogenase1 gene. Experimental Biology and Medicine, v. 235, n. 1, p. 52-56, JAN 2010. (98/14303-3)

SCHUTZ, TERESA C. B.; ANDERSEN, MONICA L.; TUFIK, SERGIO. The influence of orofacial pain on sleep pattern: A review of theory, animal models and future directions. Sleep Medicine, v. 10, n. 8, p. 822-828, SEP 2009. (98/14303-3)

ANDERSEN, MONICA L.; ALVARENGA, TATHIANA A. F.; GUINDALINI, CAMILA; PERRY, JULIANA C.; SILVA, ANDRESSA; ZAGER, ADRIANO; TUFIK, SERGIO. Paradoxical Sleep Deprivation Influences Sexual Behavior in Female Rats. Journal of Sexual Medicine, v. 6, n. 8, p. 2162-2172, AUG 2009. (06/58274-5, 07/56620-6, 06/58275-1, 98/14303-3)

SILVA, A.; ANDERSEN, M. L.; TUFIK, S.. Sleep pattern in an experimental model of osteoarthritis. Pain, v. 140, n. 3, p. 446-455, DEC 2008. (07/56620-6, 98/14303-3)

EGYDIO, F.; RUIZ, F. S.; TOMIMORI, J.; TUFIK, S.; ANDERSEN, MONICA LEVY. Can morphine interfere in the healing process during chronic stress?. ARCHIVES OF DERMATOLOGICAL RESEARCH, v. 304, n. 6, p. 413-420, AUG 2012. (07/55445-6, 98/14303-3)

MAZZOTTI, DIEGO ROBLES; GUINDALINI, CAMILA; LINO DE SOUZA, ALTAY ALVES; SATO, JOAO RICARDO; SANTOS-SILVA, ROGERIO; AZEREDO BITTENCOURT, LIA RITA; TUFIK, SERGIO. Adenosine Deaminase Polymorphism Affects Sleep EEG Spectral Power in a Large Epidemiological Sample. PLoS One, v. 7, n. 8, AUG 29 2012. (98/14303-3)

MATOS, GABRIELA; RIBEIRO, DANIEL A.; ALVARENGA, TATHIANA A.; HIROTSU, CAMILA; SCORZA, FULVIO A.; LE SUEUR-MALUF, LUCIANA; NOGUTI, JULIANA; CAVALHEIRO, ESPER A.; TUFIK, SERGIO; ANDERSEN, MONICA L.. Behavioral and genetic effects promoted by sleep deprivation in rats submitted to pilocarpine-induced status epilepticus. Neuroscience Letters, v. 515, n. 2, p. 137-140, MAY 2 2012. (09/01030-5, 98/14303-3, 10/15110-8, 10/50129-1)

SANTOS-SILVA, ROGERIO; CASTRO, LAURA SIQUEIRA; TADDEI, JOSE AUGUSTO; TUFIK, SERGIO; AZEREDO BITTENCOURT, LIA RITA. Sleep Disorders and Demand for Medical Services: Evidence from a Population-Based Longitudinal Study. PLoS One, v. 7, n. 2, FEB 1 2012. (07/50525-1, 98/14303-3)

MATOS, GABRIELA; TUFIK, SERGIO; SCORZA, FULVIO A.; CAVALHEIRO, ESPER A.; ANDERSEN, MONICA L.. Sleep, epilepsy and translational research: What can we learn from the laboratory bench?. PROGRESS IN NEUROBIOLOGY, v. 95, n. 3, p. 396-405, NOV 2011. (98/14303-3, 10/15110-8)

LUCCHESI, L. M.; HACHUL, H.; YAGIHARA, F.; SANTOS-SILVA, R.; TUFIK, S.; BITTENCOURT, L.. Does menopause influence nocturnal awakening with headache?. CLIMACTERIC, v. 16, n. 3, p. 362-368, JUN 2013. (07/50525-1, 98/14303-3)

POLESE, JESSICA FABIA; SANTOS-SILVA, ROGERIO; DE OLIVEIRA FERRARI, PAULA MARTINS; SARTORI, DENIS EDUARDO; TUFIK, SERGIO; BITTENCOURT, LIA. Is portable monitoring for diagnosing obstructive sleep apnea syndrome suitable in elderly population?. Sleep and Breathing, v. 17, n. 2, p. 679-686, MAY 2013. (07/50525-1, 98/14303-3)

TAKATSU-COLEMAN, ANDRE L.; PATTI, CAMILLA L.; ZANIN, KARINA A.; SANDAY, LEANDRO; ZAGER, ADRIANO; CARVALHO, RITA C.; ANDERSEN, MONICA L.; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Mild acute stress reactivates memory of a discriminative avoidance task in mice. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, v. 16, n. 3, p. 278-288, MAY 2013. (98/14303-3)

PELLEGRINO, R.; MAZZOTTI, D. R.; GUINDALINI, C.; SANTOS-SILVA, R.; BITTENCOURT, L. R. A.; TUFIK, S.. Apolipoprotein E polymorphisms and sleep quality in Obstructive Sleep Apnea Syndrome. Clinica Chimica Acta, v. 412, n. 23-24, p. 2223-2227, NOV 20 2011. (07/50525-1, 98/14303-3)

PADILHA, H. G.; CRISPIM, C. A.; ZIMBERG, I. Z.; DE-SOUZA, D. A.; WATERHOUSE, J.; TUFIK, S.; DE-MELLO, M. T.. A link between sleep loss, glucose metabolism and adipokines. Brazilian Journal of Medical and Biological Research, v. 44, n. 10, p. 992-999, OCT 2011. (98/14303-3)

SCHOORLEMMER, GUUS H. M.; ROSSI, MARCIO V.; TUFIK, SERGIO; CRAVO, SERGIO L.. A new method to produce obstructive sleep apnoea in conscious unrestrained rats. Experimental Physiology, v. 96, n. 10, p. 1010-1018, OCT 2011. (98/14303-3)

EGYDIO, F.; TOMIMORI, J.; TUFIK, S.; ANDERSEN, M. L.. Does sleep deprivation and morphine influence wound healing?. Medical Hypotheses, v. 77, n. 3, p. 353-355, SEP 2011. (98/14303-3)

KAHAN, VANESSA; RIBEIRO, DANIEL ARAKI; ANDERSEN, MONICA LEVY; ALVARENGA, TATHIANA APARECIDA; TUFIK, SERGIO. Sleep Loss Induces Differential Response Related To Genotoxicity in Multiple Organs of Three Different Mice Strains. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, v. 107, n. 1, p. 598-602, JUL 2010. (06/58274-5, 07/01228-4, 98/14303-3)

LLANAS, ANA CAROLINA; HACHUL, HELENA; BITTENCOURT, LIA R. A.; TUFIK, SERGIO. Physical therapy reduces insomnia symptoms in postmenopausal women. MATURITAS, v. 61, n. 3, p. 281-284, NOV 20 2008. (98/14303-3)

ALVARENGA, TATHIANA A.; PATTI, CAMILLA L.; ANDERSEN, MONICA L.; SILVA, REGINA H.; CALZAVARA, MARIANA B.; LOPEZ, GIORGIA B.; FRUSSA-FILHO, ROBERTO; TUFIK, SERGIO. Paradoxical sleep deprivation impairs acquisition, consolidation, and retrieval of a discriminative avoidance task in rats. NEUROBIOLOGY OF LEARNING AND MEMORY, v. 90, n. 4, p. 624-632, NOV 2008. (06/58274-5, 98/14303-3)

ANDERSEN, MONICA LEVY; TUFIK, SERGIO. The effects of testosterone on sleep and sleep-disordered breathing in men: Its bidirectional interaction with erectile function. SLEEP MEDICINE REVIEWS, v. 12, n. 5, p. 365-379, OCT 2008. (98/14303-3)

DUBIELA‚ F. P.; DE OLIVEIRA‚ M. G. M.; MOREIRA‚ K. D. M.; NOBREGA‚ J. N.; TUFIK‚ S.; HIPÓLIDE‚ D. C.. Learning deficits induced by sleep deprivation and recovery are not associated with altered [3H] muscimol and [3H] flunitrazepam binding. Brain Research, v. 1037, n. 1/2, p. 157-163, Mar. 2005. (98/14303-3, 02/12453-5, 01/12484-5)

GUINDALINI, CAMILA; MAZZOTTI, DIEGO R.; CASTRO, LAURA S.; D'AUREA, CAROLINA V. R.; ANDERSEN, MONICA L.; POYARES, DALVA; BITTENCOURT, LIA R. A.; TUFIK, SERGIO. Brain-Derived Neurotrophic Factor Gene Polymorphism Predicts Interindividual Variation in the Sleep Electroencephalogram. Journal of Neuroscience Research, v. 92, n. 8, p. 1018-1023, AUG 2014. (07/50525-1, 98/14303-3)

HACHUL, HELENA; ANDERSEN, MONICA L.; BITTENCOURT, LIA; SANTOS-SILVA, ROGERIO; TUFIK, SERGIO. A population-based survey on the influence of the menstrual cycle and the use of hormonal contraceptives on sleep patterns in Sao Paulo, Brazil. International Journal of Gynecology & Obstetrics, v. 120, n. 2, p. 137-140, FEB 2013. (98/14303-3)

RZEZAK, PATRICIA; MOREIRA ANTUNES, HANNA KAREN; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Tradução e adaptação transcultural do "Game Dice Task" para população brasileira. Arquivos de Neuro-Psiquiatria, v. 70, n. 12, p. 929-933, DEC 2012. (98/14303-3)

HIROTSU, CAMILA; RYDLEWSKI, MARIANA; ARAUJO, MARIANA SILVA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Sleep Loss and Cytokines Levels in an Experimental Model of Psoriasis. PLoS One, v. 7, n. 11, NOV 30 2012. (98/14303-3, 10/50129-1)

ESTEVES, ANDREA M.; LOPES, CLEIDE; FRUSSA-FILHO, ROBERTO; FRANK, MIRIAM K.; CAVAGNOLLI, DANIEL; ARIDA, RICARDO M.; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Spontaneously Hypertensive Rats: Possible Animal Model of Sleep-Related Movement Disorders. JOURNAL OF MOTOR BEHAVIOR, v. 45, n. 6, p. 487-493, NOV 1 2013. (08/50646-6, 98/14303-3)

CASTRO, LAURA S.; POYARES, DALVA; LEGER, DAMIEN; BITTENCOURT, LIA; TUFIK, SERGIO. Objective Prevalence of Insomnia in the Sao Paulo, Brazil Epidemiologic Sleep Study. ANNALS OF NEUROLOGY, v. 74, n. 4, p. 537-546, OCT 2013. (98/14303-3)

FERNANDES, JR., SILVIO DE ARAUJO; ANTONIETTI, LEANDRO STETNER; SABA, AMANDA; DE FARIA, ALEXANDRE PAULINO; ESTEVES, ANDREA MACULANO; TUFIK, SERGIO; DE MELLO, MARCO TULIO. The Impact of Shift Work on Brazilian Train Drivers with Different Chronotypes: A Comparative Analysis through Objective and Subjective Criteria. MEDICAL PRINCIPLES AND PRACTICE, v. 22, n. 4, p. 390-396, 2013. (98/14303-3)

BORGES, JULIANE GOLDONI; GINANI, GIULIANO EMERENCIANO; HACHUL, HELENA; CINTRA, FATIMA DUMAS; TUFIK, SERGIO; POMPEIA, SABINE. Executive functioning in obstructive sleep apnea syndrome patients without comorbidities: Focus on the fractionation of executive functions. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, v. 35, n. 10, p. 1094-1107, DEC 1 2013. (98/14303-3)

PERRY, JULIANA C.; GUINDALINI, CAMILA; BITTENCOURT, LIA; GARBUIO, SILVERIO; MAZZOTTI, DIEGO R.; TUFIK, SERGIO. Whole blood hypoxia-related gene expression reveals novel pathways to obstructive sleep apnea in humans. Respiratory Physiology & Neurobiology, v. 189, n. 3, p. 649-654, DEC 1 2013. (98/14303-3)

DA SILVA, PATRICIA LEAO; DE MELLO, MARCO TULIO; CHEIK, NADIA CARLA; SANCHES, PRISCILA LIMA; DE PIANO, ALINE; CORGOSINHO, FLAVIA CAMPOS; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; CARNIER, JUNE; INOUE, DANIELA; DO NASCIMENTO, CLAUDIA M. O.; et al. The Role of Pro-inflammatory and Anti-inflammatory Adipokines on Exercise-Induced Bronchospasm in Obese Adolescents Undergoing Treatment. Respiratory Care, v. 57, n. 4, p. 572-582, APR 2012. (06/00684-3, 08/53069-0, 98/14303-3)

YAGIHARA, FABIANA; LUCCHESI, LIGIA MENDONCA; D'ALMEIDA, VANIA; DE MELLO, MARCO TULIO; TUFIK, SERGIO; AZEREDO BITTENCOURT, LIA RITA. Oxidative stress and quality of life in elderly patients with obstructive sleep apnea syndrome: are there differences after six months of Continuous Positive Airway Pressure treatment?. Clinics, v. 67, n. 6, p. 565-571, 2012. (07/06232-0, 98/14303-3)

ALVARENGA, TATHIANA APARECIDA; TUFIK, SERGIO; PIRES, GABRIEL NATAN; ANDERSEN, MONICA LEVY. Influence of food restriction on lipid profile and spontaneous glucose levels in male rats subjected to paradoxical sleep deprivation. Clinics, v. 67, n. 4, p. 375-380, 2012. (11/12325-6, 10/14768-0, 98/14303-3)

SANTOS, LIGIA GABRIELLE; PIRES, GABRIEL NATAN; AZEREDO BITTENCOURT, LIA RITA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Chronobiology: Relevance for tuberculosis. TUBERCULOSIS, v. 92, n. 4, p. 293-300, JUL 2012. (98/14303-3)

DE SOUZA, LUCIANE; SMAILI, SORAYA S.; URESHINO, RODRIGO P.; SINIGAGLIA-COIMBRA, RITA; ANDERSEN, MONICA L.; LOPES, GUIOMAR S.; TUFIK, SERGIO. Effect of chronic sleep restriction and aging on calcium signaling and apoptosis in the hippocampus of young and aged animals. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 39, n. 1, p. 23-30, OCT 1 2012. (08/50424-3, 98/14303-3)

EGYDIO, FLAVIA; RIBEIRO, DANIEL ARAKI; NOGUTI, JULIANA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Influence of sleep deprivation and morphine on the expression of inducible nitric oxide synthase and cyclooxygenase-2 in skin of hairless mice. TOXICOLOGY MECHANISMS AND METHODS, v. 22, n. 8, p. 577-583, OCT 2012. (98/14303-3)

KOYAMA, RENATA G.; ESTEVES, ANDREA M.; OLIVEIRA E SILVA, LUCIANA; LIRA, FABIO S.; BITTENCOURT, LIA R. A.; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Prevalence of and risk factors for obstructive sleep apnea syndrome in Brazilian railroad workers. Sleep Medicine, v. 13, n. 8, p. 1028-1032, SEP 2012. (98/14303-3)

ACKEL-D'ELIA, CAROLINA; DA SILVA, ANTONIO CARLOS; SILVA, ROGERIO SANTOS; TRUKSINAS, EVELI; SOUSA, BOLIVAR SALDANHA; TUFIK, SERGIO; DE MELLO, MARCO TULIO; AZEREDO BITTENCOURT, LIA RITA. Effects of exercise training associated with continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome. Sleep and Breathing, v. 16, n. 3, p. 723-735, SEP 2012. (03/11037-0, 98/14303-3)

FERNANDES-SANTOS, LUCIANO; PATTI, CAMILLA L.; ZANIN, KARINA A.; FERNANDES, HELAINE A.; TUFIK, SERGIO; ANDERSEN, MONICA L.; FRUSSA-FILHO, ROBERTO. Sleep deprivation impairs emotional memory retrieval in mice: Influence of sex. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 38, n. 2, p. 216-222, AUG 7 2012. (98/14303-3)

FERNANDES, HELAINE A.; ZANIN, KARINA A.; PATTI, CAMILLA L.; WUO-SILVA, RAPHAEL; CARVALHO, RITA C.; FERNANDES-SANTOS, LUCIANO; BITTENCOURT, LIA R. A.; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Inhibitory effects of modafinil on emotional memory in mice. Neuropharmacology, v. 64, n. SI, p. 365-370, JAN 2013. (98/14303-3)

VISNIAUSKAS, BRUNA; PERRY, JULIANA C.; OLIVEIRA, VITOR; DALIO, FERNANDA M.; ANDERSEN, MONICA L.; TUFIK, SERGIO; CHAGAS, JAIR R.. Cocaine administration increases angiotensin I-converting enzyme (ACE) expression and activity in the rat striatum and frontal cortex. Neuroscience Letters, v. 506, n. 1, p. 84-88, JAN 6 2012. (98/14303-3)

BARBOSA, A. A.; PEDRAZZOLI, M.; KOIKE, B. D. V.; TUFIK, S.. Do Caucasian and Asian clocks tick differently?. Brazilian Journal of Medical and Biological Research, v. 43, n. 1, p. 96-99, JAN 2010. (98/14303-3)

ALVARENGA, TATHIANA A.; ANDERSEN, MONICA L.; RIBEIRO, DANIEL A.; ARAUJO, PAULA; HIROTSU, CAMILA; COSTA, JOSE L.; BATTISTI, MURILO C.; TUFIK, SERGIO. Single exposure to cocaine or ecstasy induces DNA damage in brain and other organs of mice. ADDICTION BIOLOGY, v. 15, n. 1, p. 96-99, JAN 2010. (09/01030-5, 07/01228-4, 98/14303-3)

PELLEGRINO, R.; SUNAGA, D. Y.; GUINDALINI, C.; MARTINS, R. C. S.; MAZZOTTI, D. R.; WEI, Z.; DAYE, Z. J.; ANDERSEN, M. L.; TUFIK, S.. Whole blood genome-wide gene expression profile in males after prolonged wakefulness and sleep recovery. Physiological Genomics, v. 44, n. 21, p. 1003-1012, NOV 2012. (98/14303-3)

ZANIN, KARINA A.; PATTI, CAMILLA L.; SANDAY, LEANDRO; FERNANDES-SANTOS, LUCIANO; OLIVEIRA, LARISSA C.; POYARES, DALVA; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Effects of zolpidem on sedation, anxiety, and memory in the plus-maze discriminative avoidance task. Psychopharmacology, v. 226, n. 3, p. 459-474, APR 2013. (08/08823-8, 09/00465-8, 98/14303-3)

SANDAY, LEANDRO; PATTI, CAMILLA L.; ZANIN, KARINA A.; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Amphetamine-induced memory impairment in a discriminative avoidance task is state-dependent in mice. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, v. 16, n. 3, p. 583-592, APR 2013. (98/14303-3)

MARAGNO-CORREA, JUSSARA M. R.; PATTI, CAMILLA L.; ZANIN, KARINA A.; WUO-SILVA, RAPHAEL; RUIZ, FRANCIELI S.; ZAGER, ADRIANO; SA-NUNES, ANDERSON; TUFIK, SERGIO; ANDERSEN, MONICA L.; FRUSSA-FILHO, ROBERTO. Sleep Deprivation Increases Mortality in Female Mice Bearing Ehrlich Ascitic Tumor. NEUROIMMUNOMODULATION, v. 20, n. 3, p. 134-140, 2013. (98/14303-3)

ANDERSEN, MONICA L.; HOSHINO, KATSUMASA; TUFIK, SERGIO. Increased susceptibility to development of anhedonia in rats with chronic peripheral nerve injury: Involvement of sleep deprivation?. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 33, n. 6, p. 960-966, AUG 31 2009. (98/14303-3)

ZANINOTTO, ANA L. C.; BUENO, ORLANDO F. A.; PRADELLA-HALLINAN, MARCIA; TUFIK, SERGIO; RUSTED, JENNY; STOUGH, CON; POMPEIA, SABINE. Acute cognitive effects of donepezil in young, healthy volunteers. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, v. 24, n. 6, p. 453-464, AUG 2009. (98/14303-3)

PERRY, JULIANA C.; BERGAMASCHI, CASSIA T.; CAMPOS, RUY R.; ANDERSEN, MONICA L.; MONTANO, NICOLA; CASARINI, DULCE E.; TUFIK, SERGIO. Sympathetic and angiotensinergic responses mediated by paradoxical sleep loss in rats. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, v. 12, n. 3, p. 146-152, SEP 2011. (98/14303-3)

AZEVEDO, EDUARDO; MANZANO, GILBERTO M.; SILVA, ANDRESSA; MARTINS, RAQUEL; ANDERSEN, MONICA L.; TUFIK, SERGIO. The effects of total and REM sleep deprivation on laser-evoked potential threshold and pain perception. Pain, v. 152, n. 9, p. 2052-2058, SEP 2011. (06/58276-8, 06/03444-3, 98/14303-3)

DATTILO, M.; ANTUNES, H. K. M.; MEDEIROS, A.; MONICO NETO, M.; SOUZA, H. S.; TUFIK, S.; DE MELLO, M. T.. Sleep and muscle recovery: Endocrinological and molecular basis for a new and promising hypothesis. Medical Hypotheses, v. 77, n. 2, p. 220-222, AUG 2011. (09/11056-1, 98/14303-3)

DALIO, FERNANDA M.; VISNIAUSKAS, BRUNA; BICOCCHI, ELIANE S.; PERRY, JULIANA C.; FREUA, RODRIGO; GESTEIRA, TARSIS F.; NADER, HELENA B.; MACHADO, MAURICIO F. M.; TUFIK, SERGIO; FERRO, EMER S.; et al. Acute cocaine treatment increases thimet oligopeptidase in the striatum of rat brain. Biochemical and Biophysical Research Communications, v. 419, n. 4, p. 724-727, MAR 23 2012. (98/14303-3)

HACHUL, HELENA; BITTENCOURT, LIA R. A.; ANDERSEN, MONICA L.; HAIDAR, MAURO A.; BARACAT, EDMUND C.; TUFIK, SERGIO. Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women. International Journal of Gynecology & Obstetrics, v. 103, n. 3, p. 207-212, DEC 2008. (98/14303-3)

HACHUL, H.; ANDERSEN, M. L.; BITTENCOURT, L. R. A.; SANTOS-SILVA, R.; CONWAY, S. G.; TUFIK, S.. Does the reproductive cycle influence sleep patterns in women with sleep complaints?. CLIMACTERIC, v. 13, n. 6, p. 594-603, DEC 2010. (98/14303-3)

FERNANDO MORGADINHO SANTOS COELHO; MÁRCIA PRADELLA-HALLINAN; GABRIELA RODRIGUES ALVES; LIA RITA AZEREDO BITTENCOURT; MÁRIO PEDRAZZOLI NETO; FÁBIO MOREIRA; SÉRGIO TUFIK. Estudo dos linfócitos T CD4, CD8 e B em pacientes com narcolepsia. Arquivos de Neuro-Psiquiatria, v. 65, p. 423-427, 2007-06-00. (98/14303-3)

SCHÜTZ‚ TCB; ANDERSEN‚ ML; TUFIK‚ S.. Sleep alterations in an experimental orofacial pain model in rats. Brain Research, v. 993, n. 1, p. 164-171, 2003. (98/14303-3)

ANDERSEN, MONICA L.; ALVARENGA, TATHIANA A.; SCORZA, FULVIO A.; MATOS, GABRIELA; SONODA, ELIZA Y.; HIROTSU, CAMILA; CAVALHEIRO, ESPER A.; TUFIK, SERGIO. Impairment of Sexual Function in Rats with Epilepsy. Journal of Sexual Medicine, v. 9, n. 9, p. 2266-2272, SEP 2012. (98/14303-3, 11/12325-6, 09/01030-5, 09/14206-4, 10/50129-1)

SILVA, R. H.; ABÍLIO, V. C.; TAKATSU, A. L.; KAMEDA, S. R.; GRASSL, C.; CHEHIN, A. B.; MEDRANO, W. A.; CALZAVARA, M. B.; REGISTRO, S.; ANDERSEN, M. L.; et al. Role of hippocampal oxidative stress in memory deficits induced by sleep deprivation in mice. Neuropharmacology, v. 46, n. 6, p. 895-903, May 2004. (01/10713-7, 98/14303-3)

ANDERSEN, M. LEVY; BIGNOTTO, M.; TUFIK, S.. Hormone treatment facilitates penile erection in castrated rats after sleep deprivation and cocaine. Journal of Neuroendocrinology, v. 16, n. 2, p. 154-159, Feb. 2004. (98/14303-3, 01/04329-0)

ANTUNES, ISABELA B.; ANDERSEN, MONICA L.; BARACAT, EDMUNDO C.; TUFIK, SERGIO. The effects of paradoxical sleep deprivation on estrous cycles of the female rats. Hormones and Behavior, v. 49, n. 4, p. 433-440, Apr. 2006. (98/14303-3, 04/03979-9, 01/04329-0)

PEREIRA‚ D.S.; PEDRAZZOLI‚ M.; KOIKE‚ B.D.V.; LOUZADA‚ F.M.; BENEDITO-SILVA‚ A.A.; LOPEZ‚ A.R.; TUFIK‚ S.. The G619A Aa-nat gene polymorphism does not contribute to sleep time variation in the Brazilian population. BEHAVIOR GENETICS, v. 37, n. 4, p. 637-638, 2007. (98/14303-3)

FRUSSA-FILHO‚ R.; GONÇALVES‚ M.T.M.; ANDERSEN‚ M.L.; DE ARAUJO‚ N.P.; CHINEN‚ C.C.; TUFIK‚ S.. Paradoxical sleep deprivation potentiates amphetamine-induced behavioural sensitization by increasing its conditioned component. Brain Research, v. 1003, n. 1, p. 188-193, 2004. (98/14303-3, 98/13611-6)

PEDRAZZOLI‚ M.; D’ALMEIDA‚ V.; MARTINS‚ P.J.F.; MACHADO‚ R.B.; LING‚ L.; NISHINO‚ S.; TUFIK‚ S.; MIGNOT‚ E.. Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation. Brain Research, v. 995, n. 1, p. 1-6, 2004. (98/14303-3)

RABONI‚ M.R.; TUFIK‚ S.; SUCHECKI‚ D.. Treatment of PTSD by eye movement desensitization reprocessing (EMDR) improves sleep quality‚ quality of life‚ and perception of stress. Annals of the New York Academy of Sciences, v. 1071, n. 1, p. 508-513, 2006. (98/14303-3)

ANDERSEN‚ M.L.; BIGNOTTO‚ M.; TUFIK‚ S.. Cocaine-induced genital reflexes during paradoxical sleep deprivation and recovery. Physiology & Behavior, v. 78, n. 2, p. 255-259, 2003. (98/14303-3)

ANDERSEN‚ M.L.; PAPALE‚ L.A.; TUFIK‚ S.. Diurnal variation in the genital reflexes and hormone levels induced by paradoxical sleep deprivation and cocaine in male rats. Brain Research Bulletin, v. 64, n. 3, p. 215-220, 2004. (98/14303-3)

ANDERSEN‚ M.L.; TUFIK‚ S.. The effects of dopaminergic agonists on genital reflexes in paradoxical sleep-deprived male rats. Physiology & Behavior, v. 84, n. 2, p. 205-210, 2005. (98/14303-3)

TIBA‚ P.A.; PALMA‚ B.D.; TUFIK‚ S.; SUCHECKI‚ D.. Effects of early handling on basal and stress-induced sleep parameters in rats. Brain Research, v. 975, n. 1, p. 158-166, 2003. (98/14303-3)

ALMEIDA‚ T.F.; ROIZENBLATT‚ S.; BENEDITO-SILVA‚ A.A.; TUFIK‚ S.. The effect of combined therapy (ultrasound and interferential current) on pain and sleep in fibromyalgia. Pain, v. 104, n. 3, p. 665-672, 2003. (98/14303-3)

MENEZES‚ M.C.R.; NOGUEIRA PIRES‚ M.L.; BENEDITO-SILVA‚ A.A.; TUFIK‚ S.. Sleep parameters among offshore workers: an initial assessment in the Campos Basin‚ Rio de Janeiro‚ Brazil. CHRONOBIOLOGY INTERNATIONAL, v. 21, n. 6, p. 889-897, 2004. (98/14303-3)

ALMEIDA‚ T.F.; ROIZENBLATT‚ S.; TUFIK‚ S.. Afferent pain pathways: a neuroanatomical review. Brain Research, v. 1000, n. 1, p. 40-56, 2004. (98/14303-3)

LEVY ANDERSEN‚ M.; BIGNOTTO‚ M.; TUFIK‚ S.. Facilitation of ejaculation after methamphetamine administration in paradoxical sleep deprived rats. Brain Research, v. 978, n. 1, p. 31-37, 2003. (98/14303-3)

CALZAVARA‚ MB; PATTI‚ CL; LOPEZ‚ GB; ABILIO‚ VC; SILVA‚ RH; FRUSSA-FILHO‚ R.. Role of learning of open arm avoidance in the phenomenon of one-trial tolerance to the anxiolytic effect of chlordiazepoxide in mice. Life Sciences, v. 76, n. 19, p. 2235-2246, 2005. (98/14303-3, 01/10713-7)

DE FARIA‚ A.P.; CAVAGNOLLI‚ D.A.; ROSSI‚ M.V.; FERREIRA‚ S.E.; BITTENCOURT‚ L.R.A.; TUFIK‚ S.; DE MELLO‚ M.T.. Effects of Resistance Exercise on the Sleep Patterns of Sedentary Individuals. Sleep, v. 2, n. 3, p. 141-146, 2009. (98/14303-3)

ANTUNES‚ IB; ANDERSEN‚ ML; ALVARENGA‚ TAF; TUFIK‚ S.. Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in intact and ovariectomized rats compared with male rats. Behavioural Brain Research, v. 176, n. 2, p. 187-192, 2007. (98/14303-3, 04/03979-9)

MACHADO‚ R.B.; SUCHECKI‚ D.; TUFIK‚ S.. Comparison of the sleep pattern throughout a protocol of chronic sleep restriction induced by two methods of paradoxical sleep deprivation. Brain Research Bulletin, v. 70, n. 3, p. 213-220, 2006. (98/14303-3)

KOYAMA‚ R.G.; DRAGER‚ L.F.; LORENZI-FILHO‚ G.; CINTRA‚ F.D.; PEREIRA‚ A.C.; POYARES‚ D.; KRIEGER‚ J.E.; CASTRO‚ R.M.; TUFIK‚ S.; DE MELLO‚ M.T.; et al. Reciprocal interactions of obstructive sleep apnea and hypertension associated with ACE I/D polymorphism in males. Sleep Medicine, v. 10, n. 10, p. 1107-1111, 2009. (98/14303-3, 05/57504-4)

PIAUILINO‚ DC; BUENO‚ OFA; TUFIK‚ S.; BITTENCOURT‚ LR; SANTOS-SILVA‚ R.; HACHUL‚ H.; GORENSTEIN‚ C.; POMPÉIA‚ S.. The Prospective and Retrospective Memory Questionnaire: A population-based random sampling study. MEMORY, v. 18, n. 4, p. 413-426, 2010. (98/14303-3, 06/05847-8)

GUSTAVO BRUNIERA PERES FERNANDES; SERGIO TUFIK; FERNANDO MORGADINHO SANTOS COELHO. Vacinação para pandemia de influenza (H1N1) – um fator de risco pouco reconhecido a muitas complicações do sistema nervoso central no Brasil. Arquivos de Neuro-Psiquiatria, v. 73, n. 1, p. 72-72, 2015-01-00. (98/14303-3)

ESTEVES, ANDREA M.; LOPES, CLEIDE; FRANK, MIRIAM K.; ARIDA, RICARDO M.; FRUSSA-FILHO, ROBERTO; TUFIK, SERGIO; DE MELLO, MARCO TULIN. Can physical exercise have a protective effect in an animal model of sleep-related movement disorder?. Brain Research, v. 1639, p. 47-57, MAY 15 2016. (98/14303-3, 08/50646-6)

ANDAKU, DANIELA KUGUIMOTO; D'ALMEIDA, VANIA; CARNEIRO, GLAUCIA; HIX, SONIA; TUFIK, SERGIO; TOGEIRO, SONIA MARIA. Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study. RESPIRATORY RESEARCH, v. 16, JAN 14 2015. (98/14303-3)

R.C.S MARTINS; M.L ANDERSEN; M.C SHIH; S TUFIK. Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats. Brazilian Journal of Medical and Biological Research, v. 41, n. 1, p. 68-77, 2008-01-00. (06/58276-8, 01/04329-0, 98/14303-3)

S.G. CONWAY; S.S. ROIZENBLATT; L. PALOMBINI; L.S. CASTRO; L.R.A. BITTENCOURT; R.S. SILVA; S. TUFIK. Effect of smoking habits on sleep. Brazilian Journal of Medical and Biological Research, v. 41, n. 8, p. 722-727, 2008-08-00. (98/14303-3)

MARCO TÚLIO DE MELLO; ANA R. DÂMASO; HANNA KAREN M. ANTUNES; KÃLI O. SIQUEIRA; MARISE LAZARETTI CASTRO; SHEILA V. BERTOLINO; SÉRGIO G. STELLA; SÉRGIO TUFIK. Avaliação da composição corporal em adolescentes obesos: o uso de dois diferentes métodos. Revista Brasileira de Medicina do Esporte, v. 11, n. 5, p. 267-270, 2005-10-00. (98/14303-3)

A. SILVA; M.L. ANDERSEN; M.T. DE MELLO; L.R.A. BITTENCOURT; D. PERUZZO; S. TUFIK. Gender and age differences in polysomnography findings and sleep complaints of patients referred to a sleep laboratory. Brazilian Journal of Medical and Biological Research, v. 41, n. 12, p. 1067-1075, 2008-12-00. (07/56620-6, 98/14303-3)

ANA R. DÂMASO; LIAN TOCK; SÉRGIO TUFIK; WAGNER L. PRADO; SÉRGIO G. STELLA; MAURO FISBERG; ISA P. CINTRA; DANIELLE A. CARANTI; KÃLI O. SIQUEIRA; CLÁUDIA M. NASCIMENTO; et al. Tratamento multidisciplinar reduz o tecido adiposo visceral, leptina, grelina e a prevalência de esteatose hepática não alcoólica (NAFLD) em adolescentes obesos. Revista Brasileira de Medicina do Esporte, v. 12, n. 5, p. 263-267, 2006-10-00. (98/14303-3)

RABONI, MARA R.; ALONSO, FABIANA F. D.; TUFIK, SERGIO; SUCHECKI, DEBORAH. Improvement of mood and sleep alterations in posttraumatic stress disorder patients by eye movement desensitization and reprocessing. FRONTIERS IN BEHAVIORAL NEUROSCIENCE, v. 8, JUN 10 2014. (98/14303-3)

MOTA, MARIA CARLIANA; DE-SOUZA, DAUREA ABADIA; ROSSATO, LUANA THOMAZETTO; SILVA, CATARINA MENDES; JEHA ARAUJO, MARIA BERNADETE; TUFIK, SERGIO; DE MELLO, MARCO TULIO; CRISPIM, CIBELE APARECIDA. Dietary Patterns, Metabolic Markers and Subjective Sleep Measures in Resident Physicians. CHRONOBIOLOGY INTERNATIONAL, v. 30, n. 8, p. 1032-1041, 2013. (98/14303-3)

IRENE GUARIDO LUZ BITTAR; RICARDO LUIS FERNANDES GUERRA; FABÍOLA CRISTINA LOPES; MARCO TÚLIO DE MELLO; HANNA KAREN MOREIRA ANTUNES. Efeitos de um programa de jogos pré-desportivos nos aspectos psicobiológicos de idosas. Rev. bras. geriatr. gerontol., v. 16, n. 4, p. 713-725, 2013-12-00. (98/14303-3)

B.D. PALMA; D.C. HIPOLIDE; S. TUFIK. Effects on prolactin secretion and binding to dopaminergic receptors in sleep-deprived lupus-prone mice. Brazilian Journal of Medical and Biological Research, v. 42, n. 3, p. 299-304, 2009-03-00. (01/07263-0, 98/14303-3)

DE MELLO, MARCO TULIO; LEMOS, VALDIR DE AQUINO; MOREIRA ANTUNES, HANNA KAREN; BITTENCOURT, LIA; SANTOS-SILVA, ROGERIO; TUFIK, SERGIO. Relationship between physical activity and depression and anxiety symptoms: A population study. Journal of Affective Disorders, v. 149, n. 1-3, p. 241-246, JUL 2013. (07/50525-1, 98/14303-3)

TAKATSU-COLEMAN, ANDRE L.; PATTI, CAMILLA L.; ZANIN, KARINA A.; ZAGER, ADRIANO; CARVALHO, RITA C.; BORCOI, ALINE R.; CECCON, LILIANE M. B.; BERRO, LAIS F.; TUFIK, SERGIO; ANDERSEN, MONICA L.; et al. Short-term social isolation induces depressive-like behaviour and reinstates the retrieval of an aversive task: Mood-congruent memory in male mice?. JOURNAL OF PSYCHIATRY & NEUROSCIENCE, v. 38, n. 4, p. 259-268, JUL 2013. (98/14303-3)

MONICO-NETO, M.; ANTUNES, H. K. M.; DATTILO, M.; MEDEIROS, A.; SOUZA, H. S.; LEE, K. S.; DE MELO, C. M.; TUFIK, S.; DE MELLO, M. T.. Resistance exercise: A non-pharmacological strategy to minimize or reverse sleep deprivation-induced muscle atrophy. Medical Hypotheses, v. 80, n. 6, p. 701-705, JUN 2013. (11/15962-7, 98/14303-3)

TOGEIRO, SONIA M.; CARNEIRO, GLAUCIA; RIBEIRO FILHO, FERNANDO F.; ZANELLA, MARIA T.; SANTOS-SILVA, ROGERIO; TADDEI, JOSE A.; BITTENCOURT, LIA R. A.; TUFIK, SERGIO. Consequences of Obstructive Sleep Apnea on Metabolic Profile: A Population-Based Survey. OBESITY, v. 21, n. 4, p. 847-851, APR 2013. (98/14303-3, 07/50525-1)

TENORIO, NEULI M.; TUFIK, SERGIO; BERGAMASCHI, CASSIA T.; CAMPOS, RUY R.; CINTRA, FATIMA; ALVARENGA, TATHIANA A.; ANDERSEN, MONICA L.. Influence of Acute Sleep Deprivation on Cardiovascular Parameters in Female Zucker Obese and Lean Rats. OBESITY, v. 21, n. 3, p. 510-515, MAR 2013. (98/14303-3)

DA SILVA, PATRICIA LEAO; DE MELLO, MARCO TULIO; CHEIK, NADIA CARLA; SANCHES, PRISCILA LIMA; CORREIA, FABIOLA ALVISE; DE PIANO, ALINE; CORGOSINHO, FLAVIA CAMPOS; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; DO NASCIMENTO, CLAUDIA M. O.; OYAMA, LILA M.; et al. Interdisciplinary therapy improves biomarkers profile and lung function in asthmatic obese adolescents. PEDIATRIC PULMONOLOGY, v. 47, n. 1, p. 8-17, JAN 2012. (06/00684-3, 08/53069-0, 98/14303-3)

ZAGER, ADRIANO; RUIZ, FRANCIELI SILVA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Immune Outcomes of Paradoxical Sleep Deprivation on Cellular Distribution in Naive and Lipopolysaccharide-Stimulated Mice. NEUROIMMUNOMODULATION, v. 19, n. 2, p. 79-87, 2012. (06/58275-1, 07/55445-6, 98/14303-3)

CRISPIM, CIBELE APARECIDA; WATERHOUSE, JIM; DAMASO, ANA RAIMUNDA; ZIMBERG, IONA ZALCMAN; PADILHA, HELOISA GUARITA; OYAMA, LILA MISSAE; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Hormonal appetite control is altered by shift work: a preliminary study. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 60, n. 12, p. 1726-1735, DEC 2011. (98/14303-3)

TUFIK, SERGIO; ANDERSEN, MONICA L.; BITTENCOURT, LIA R. A.; DE MELLO, MARCO T.. Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research. Anais da Academia Brasileira de Ciências, v. 81, n. 3, p. 521-538, SEP 2009. (98/14303-3)

PIRES, M. L. N.; TEIXEIRA, C. W.; ESTEVES, A. M.; BITTENCOURT, L. R. A.; SILVA, R. S.; SANTOS, R. F.; TUFIK, S.; MELLO, M. T.. Sleep, ageing and night work. Brazilian Journal of Medical and Biological Research, v. 42, n. 9, p. 839-843, SEP 2009. (98/14303-3)

TANG, BIN; DUTT, KARONI; PAPALE, LIGIA; RUSCONI, RAFFAELLA; SHANKAR, ANUPAMA; HUNTER, JESSICA; TUFIK, SERGIO; YU, FRANK H.; CATTERALL, WILLIAM A.; MANTEGAZZA, MASSIMO; et al. A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS plus ) mutation. Neurobiology of Disease, v. 35, n. 1, p. 91-102, JUL 2009. (98/14303-3)

SCHUTZ, T. C. B.; ANDERSEN, M. L.; SILVA, A.; TUFIK, S.. Distinct Gender-related Sleep Pattern in an Acute Model of TMJ Pain. JOURNAL OF DENTAL RESEARCH, v. 88, n. 5, p. 471-476, MAY 2009. (07/56620-6, 98/14303-3)

VISNIAUSKAS, BRUNA; OLIVEIRA, VITOR; CARMONA, ADRIANA K.; D'ALMEIDA, VANIA; DE MELO, ROBSON L.; TUFIK, SERGIO; CHAGAS, JAIR R.. Angiotensin I-converting enzyme (ACE) activity and expression in rat central nervous system after sleep deprivation. Biological Chemistry, v. 392, n. 6, p. 547-553, APR 2011. (98/14303-3)

NATAL, CESAR L.; LOURENCO, TANIA J.; SILVA, LUANA A.; BOSCOLO, RITA A.; SILVA, ANDRESSA; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Diferenças nos hábitos de sono entre gêneros nos escolares de 11 a 13 anos de idade. Revista Brasileira de Psiquiatria, v. 31, n. 4, p. 358-361, DEC 2009. (07/56620-6, 98/14303-3, 06/05210-0)

KAHAN, V.; ANDERSEN, M. L.; TOMIMORI, J.; TUFIK, S.. Stress, immunity and skin collagen integrity: Evidence from animal models and clinical conditions. BRAIN BEHAVIOR AND IMMUNITY, v. 23, n. 8, p. 1089-1095, NOV 2009. (98/14303-3)

BARROS SCHUETZA, TERESA CRISTINA; DOMINGUEZ, GLADYS CRISTINA; HALLINAN, MARCIA PRADELLA; ABRAHAO CUNHA, THAYS CROSARA; TUFIK, SERGIO. Class II correction improves nocturnal breathing in adolescents. ANGLE ORTHODONTIST, v. 81, n. 2, p. 222-228, MAR 2011. (98/14303-3)

HIROTSU, CAMILA; TUFIK, SERGIO; RIBEIRO, DANIEL A.; ALVARENGA, TATHIANA A.; ANDERSEN, MONICA L.. Genomic damage in the progression of chronic kidney disease in rats. BRAIN BEHAVIOR AND IMMUNITY, v. 25, n. 3, p. 416-422, MAR 2011. (07/01228-4, 10/50129-1, 98/14303-3)

ANDERSEN, MONICA L.; ALVARENGA, TATHIANA A.; MAZZOTTI, DIEGO R.; GUINDALINI, CAMILA; PELLEGRINO, RENATA; BARRUECO, KARINA F.; SANTOS-SILVA, ROGERIO; BITTENCOURT, LIA R.; TUFIK, SERGIO. Hormonal profile, the PROGINS polymorphism, and erectile dysfunction complaints: data from a population-based survey. Fertility and Sterility, v. 95, n. 2, p. 621-624, FEB 2011. (07/50525-1, 09/01030-5, 98/14303-3)

CARNIER‚ J.; LOFRANO‚ M.C.; PRADO‚ W.L.; CARANTI‚ D.A.; DE PIANO‚ A.; TOCK‚ L.; DO NASCIMENTO‚ C.M.O.; OYAMA‚ L.M.; MELLO‚ M.T.; TUFIK‚ S.; et al. Hormonal alteration in obese adolescents with eating disorder: effects of multidisciplinary therapy. Hormone Research in Paediatrics, v. 70, n. 2, p. 79-84, 2008. (06/00684-3, 98/14303-3)

PIOVEZAN, RONALDO D.; HIROTSU, CAMILA; FERES, MARCIA C.; CINTRA, FATIMA D.; ANDERSEN, MONICA L.; TUFIK, SERGIO; POYARES, DALVA. Obstructive sleep apnea and objective short sleep duration are independently associated with the risk of serum vitamin D deficiency. PLoS One, v. 12, n. 7, JUL 7 2017. (14/15259-2, 98/14303-3)

MACHADO, RICARDO BORGES; SUCHECKI, DEBORAH. Neuroendocrine and Peptidergic Regulation of Stress-Induced REM Sleep Rebound. FRONTIERS IN ENDOCRINOLOGY, v. 7, DEC 23 2016. (98/14303-3, 10/09087-3, 15/26364-4)

MELISE OLIVEIRA MARIANO; ANDREA MACULANO ESTEVES; MIRIAM KANNEBLEY FRANK; LUCIANA CHAGAS CAPERUTO; MAURO MANCONI; SERGIO TUFIK; MARCO TULIO DE MELLO. Alterações no comportamento motor de ratas prenhes: bases para um possível modelo animal da síndrome das pernas inquietas. Revista Brasileira de Ginecologia e Obstetrícia, v. 36, n. 10, p. 436-441, 2014-10-03. (98/14303-3)

RAMOS, ADRIANA T.; TUFIK, SERGIO; TRONCONE, LANFRANCO R. P.. Control of Stress-Induced ACTH Secretion by Vasopressin and CRH: Additional Evidence. NEUROPSYCHOBIOLOGY, v. 73, n. 3, p. 184-190, 2016. (15/08098-5, 98/14303-3, 13/18897-7, 04/12871-7)

ROIZENBLATT, SUELY; SOUZA, ALTAY L.; PALOMBINI, LUCIANA; GODOY, LUCIANA M.; TUFIK, SERGIO; BITTENCOURT, LIA RITA A.. Musculoskeletal Pain as a Marker of Health Quality. Findings from the Epidemiological Sleep Study among the Adult Population of Sao Paulo City. PLoS One, v. 10, n. 11, NOV 24 2015. (98/14303-3)

MOTA, MARIA CARLIANA; WATERHOUSE, JIM; DE-SOUZA, DAUREA ABADIA; ROSSATO, LUANA THOMAZETTO; SILVA, CATARINA MENDES; JEHA ARAUJO, MARIA BERNADETE; TUFIK, SERGIO; DE MELLO, MARCO TULIO; CRISPIM, CIBELE APARECIDA. Sleep pattern is associated with adipokine levels and nutritional markers in resident physicians. CHRONOBIOLOGY INTERNATIONAL, v. 31, n. 10, p. 1130-1138, DEC 2014. (98/14303-3)

ANTUNES, H. K.; DE MELLO, M. T.; SANTOS-GALDUROZ, R. F.; GALDUROZ, J. C. F.; AQUINO LEMOS, V.; TUFIK, S.; BUENO, O. F. A.. Effects of a physical fitness program on memory and blood viscosity in sedentary elderly men. Brazilian Journal of Medical and Biological Research, v. 48, n. 9, p. 805-812, SEP 2015. (98/14303-3)

PEDRAZZOLI, MARIO; MAZZOTTI, DIEGO ROBLES; RIBEIRO, AMANDA OLIVEIRA; MENDES, JULIANA VIANA; BITTENCOURT, LIA RITA AZEREDO; TUFIK, SERGIO. A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram. PLoS One, v. 15, n. 7, JUL 9 2020. (11/05804-5, 98/14303-3)

DATTILO, MURILO; MOREIRA ANTUNES, HANNA KAREN; NUNES GALBES, NADINE MARQUES; MONICO-NETO, MARCOS; SOUZA, HELTON DE SA; LUCIO DOS SANTOS QUARESMA, MARCUS VINICIUS; LEE, KIL SUN; UGRINOWITSCH, CARLOS; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Effects of Sleep Deprivation on Acute Skeletal Muscle Recovery after Exercise. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 52, n. 2, p. 507-514, FEB 2020. (98/14303-3, 10/07005-0)

MONICO-NETO, MARCOS; MOREIRA ANTUNES, HANNA KAREN; THOMATIELI DOS SANTOS, RONALDO VAGNER; D'ALMEIDA, VANIA; LINO DE SOUZA, ALTAY ALVES; AZEREDO BITTENCOURT, LIA RITA; TUFIK, SERGIO. Physical activity as a moderator for obstructive sleep apnoea and cardiometabolic risk in the EPISONO study. European Respiratory Journal, v. 52, n. 4, OCT 1 2018. (13/00152-5, 98/14303-3)

FERNANDO MORGADINHO SANTOS COELHO; MÁRCIA PRADELLA-HALLINAN; MARIO PEDRAZZOLI; CARLOS AUGUSTO SENNE SOARES; GUSTAVO BRUNIERA PERES FERNANDES; ANDRÉ LEITE GONÇALVES; SERGIO TUFIK; LIA RITA AZEREDO BITTENCOURT. Biomarcadores tradicionias em narcolepsia: experiência de um centro de sono brasileiro. Arquivos de Neuro-Psiquiatria, v. 68, n. 5, p. 712-715, 2010-10-00. (98/14303-3)

RZEZAK, PATRICIA; CAXA, LUCIANA; SANTOLIA, PATRICIA; ANTUNES, HANNA K. M.; SURIANO, ITALO; TUFIK, SERGIO; DE MELLO, MARCO T.. Affective responses after different intensities of exercise in patients with traumatic brain injury. FRONTIERS IN PSYCHOLOGY, v. 6, JUN 25 2015. (12/13065-0, 98/14303-3)

CAVAGNOLLI, DANIEL A.; ESTEVES, ANDREA MACULANO; ACKEL-D'ELIA, CAROLINA; MAEDA, MARILIA Y.; DE FARIA, ALEXANDRE PAULINO; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Aerobic exercise does not change C-reactive protein levels in non-obese patients with obstructive sleep apnoea. European Journal of Sport Science, v. 14, n. 1, p. S142-S147, JAN 1 2014. (98/14303-3)

RUIZ, FRANCIELI SILVA; ANDERSEN, MONICA LEVY; GUINDALINI, CAMILA; ARAUJO, LEANDRO PIRES; LOPES, JOSE DANIEL; TUFIK, SERGIO. Sleep influences the immune response and the rejection process alters sleep pattern: Evidence from a skin allograft model in mice. BRAIN BEHAVIOR AND IMMUNITY, v. 61, p. 274-288, MAR 2017. (07/55445-6, 98/14303-3)

MONICO-NETO, MARCOS; MOREIRA ANTUNES, HANNA KAREN; LEE, KIL SUN; PHILLIPS, STUART M.; DE CAMPOS GIAMPA, SARA QUAGLIA; SOUZA, HELTON DE SA; DATTILO, MURILO; MEDEIROS, ALESSANDRA; DE MORAES, WILSON MAX; TUFIK, SERGIO; et al. Resistance training minimizes catabolic effects induced by sleep deprivation in rats. APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, v. 40, n. 11, p. 1143-1150, NOV 2015. (13/00152-5, 11/15962-7, 98/14303-3)

MONICO-NETO, MARCOS; DE CAMPOS GIAMPA, SARA QUAGLIA; LEE, KIL SUN; DE MELO, CAMILA MARIA; SOUZA, HELTON DE SA; DATTILO, MURILO; MINALI, PAULO ALEXANDRE; SANTOS PRADO, PEDRO HENRIQUE; TUFIK, SERGIO; DE MELLO, MARCO TULIO; et al. Negative Energy Balance Induced by Paradoxical Sleep Deprivation Causes Multicompartmental Changes in Adipose Tissue and Skeletal Muscle. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2015. (13/00152-5, 11/15962-7, 98/14303-3)

MACHADO, RICARDO BORGES; ROCHA, MURILO RAMOS; SUCHECKI, DEBORAH. Brain prolactin is involved in stress-induced REM sleep rebound. Hormones and Behavior, v. 89, p. 38-47, MAR 2017. (98/14303-3, 10/09087-3)

ANDREA MACULANO ESTEVES; ANDRESSA SILVA; AMAURY BARRETO; DANIEL ALVES CAVAGNOLLI; LUCIANA SANTO ANDREA ORTEGA; ANDREW PARSONS; EDILSON ROCHA TUBIBA; MURILO BARRETO; WINCKLER DE OLIVEIRA FILHO; SERGIO TUFIK; et al. Avaliação da qualidade de vida e do sono de atletas paralímpicos brasileiros. Revista Brasileira de Medicina do Esporte, v. 21, n. 1, p. 53-56, 2015-02-00. (98/14303-3)

HANNA KAREN MOREIRA ANTUNES; RUTH FERREIRA SANTOS-GALDUROZ; RAFAEL EDUARDO EUSTÓRGIO PINHEIRO CHAGAS MIRANDA; RICARDO CARDOSO CASSILHAS; ORLANDO FRANCISCO AMODEU BUENO; MARCO TÚLIO DE MELLO. O baixo consumo de oxigênio tem reflexos nos escores de depressão em idosos. Rev. bras. geriatr. gerontol., v. 17, n. 3, p. 505-515, 2014-09-00. (98/14303-3)

M.L. ANDERSEN; M. BIGNOTTO; S. TUFIK. Effect of sildenafil (Viagra®) on the genital reflexes of paradoxical sleep-deprived male rats. Brazilian Journal of Medical and Biological Research, v. 40, n. 11, p. 1473-1480, 2007-10-22. (01/04329-0, 98/14303-3)

S.G. CONWAY; S. TUFIK; R. FRUSSA FILHO; L.R.A. BITTENCOURT. Repercussions of a sleep medicine outreach program. Brazilian Journal of Medical and Biological Research, v. 39, n. 8, p. 1057-1063, 2006-08-00. (98/14303-3)

R.C. MARTINS; M.L. ANDERSEN; S. TUFIK. The reciprocal interaction between sleep and type 2 diabetes mellitus: facts and perspectives. Brazilian Journal of Medical and Biological Research, v. 41, n. 3, p. 180-187, 2007-11-26. (06/58276-8, 98/14303-3)

C.A. SANTOS; M.L. ANDERSEN; M.M.S. LIMA; S. TUFIK. Gentle handling temporarily increases c-Fos in the substantia nigra pars compacta. Brazilian Journal of Medical and Biological Research, v. 41, n. 10, p. 920-925, 2008-09-30. (98/14303-3)

S.R. PANDI-PERUMAL; J.C. VERSTER; L. KAYUMOV; A.D. LOWE; M.G. SANTANA; M.L.N. PIRES; S. TUFIK; M.T. MELLO. Sleep disorders, sleepiness and traffic safety: a public health menace. Brazilian Journal of Medical and Biological Research, v. 39, n. 7, p. 863-871, 2006-07-00. (98/14303-3)

MARCOS G. SANTANA; SERGIO TUFIK; GISELLE S. PASSOS; DONALD M. SANTEE; BENEDITO S. DENADAI; MARCO T. MELLO. Comparação entre diferentes métodos de análise do componente lento do consumo de oxigênio: uma abordagem no domínio muito intenso de exercício. Revista Brasileira de Medicina do Esporte, v. 13, n. 4, p. 241-244, 2007-08-00. (98/14303-3)

EGYDIO, FLAVIA; PIRES, GABRIEL NATAN; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Wound-healing and benzodiazepines: does sleep play a role in this relationship?. Clinics, v. 67, n. 7, p. 827-830, 2012. (10/14768-0, 98/14303-3, 11/14462-0)

PEDRAZZOLI, MARIO; SECOLIN, RODRIGO; BASTOS ESTEVES, LUIZ OTAVIO; PEREIRA, DANYELLA SILVA; KOIKE, BRUNA DEL VECHIO; LOUZADA, FERNANDO MAZZILI; LOPES-CENDES, ISCIA; TUFIK, SERGIO. Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans. GENETICS AND MOLECULAR BIOLOGY, v. 33, n. 4, p. 627-632, 2010. (98/14303-3)

MOTA, MARIA CARLIANA; WATERHOUSE, JIM; DE-SOUZA, DAUREA ABADIA; ROSSATO, LUANA THOMAZETTO; SILVA, CATARINA MENDES; JEHA ARAUJO, MARIA BERNADETE; TUFIK, SERGIO; DE MELLO, MARCO TULIO; CRISPIM, CIBELE APARECIDA. Association between chronotype, food intake and physical activity in medical residents. CHRONOBIOLOGY INTERNATIONAL, v. 33, n. 6, SI, p. 730-739, 2016. (98/14303-3)

A.A. BARBOSA; M.A.L. MIGUEL; S. TUFIK; F.C. SABINO; M.S. CENDOROGLO; M. PEDRAZZOLI. Sleep disorder or simple sleep ontogeny? Tendency for morningness is associated with worse sleep quality in the elderly. Brazilian Journal of Medical and Biological Research, v. 49, n. 10, 2016-10-10. (11/05804-5, 98/14303-3)

FERNANDES-JUNIOR, SILVIO ARAUJO; RUIZ, FRANCIELI SILVA; ANTONIETTI, LEANDRO STETNER; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Sleep, Fatigue and Quality of Life: A Comparative Analysis among Night Shift Workers with and without Children. PLoS One, v. 11, n. 7, JUL 8 2016. (98/14303-3)

MELLO-FUJITA, LUCIANE; KIM, LENISE JIHE; PALOMBINI, LUCIANA DE OLIVEIRA; RIZZI, CAMILA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY; COELHO, FERNANDO MORGADINHO. Treatment of obstructive sleep apnea syndrome associated with stroke. Sleep Medicine, v. 16, n. 6, p. 691-696, JUN 2015. (13/14420-1, 98/14303-3)

KAREN Y. YAMADA; SUSAN Y. SATAKE; JULIANA C. PERRY; KARINA O. GARCIA; VÂNIA D'ALMEIDA; SERGIO TUFIK; BEATRIZ M. LONGO; REGINA C. BARBOSA-SILVA. Effect of postnatal intermittent hypoxia on locomotor activity and neuronal development in rats tested in early adulthood. Psychology & Neuroscience, v. 7, n. 2, p. 125-130, 2014-05-27. (06/61223-3, 10/00120-8, 09/07347-0, 09/07278-9, 09/03616-7, 98/14303-3)

GISELLE S. PASSOS; MARCOS G. SANTANA; DALVA POYARES; CAROLINA V. DAUREA; ALEXANDRE A. TEIXEIRA; SERGIO TUFIK; MARCO T. DE MELLO. Chronotype and anxiety are associated in patients with chronic primary insomnia. Revista Brasileira de Psiquiatria, v. 39, n. 2, p. 183-186, 2017-01-09. (08/02862-1, 98/14303-3)

GOULART, LEONARDO I.; PINTO, JR., LUCIANO R.; PERLIS, MICHAEL L.; MARTINS, RAQUEL; CABOCLO, LUIS OTAVIO; TUFIK, SERGIO; ANDERSEN, MONICA L.. Effects of different sleep deprivation protocols on sleep perception in healthy volunteers. Sleep Medicine, v. 15, n. 10, p. 1219-1224, OCT 2014. (06/58276-8, 98/14303-3)

PASSOS, GISELLE SOARES; POYARES, DALVA; SANTANA, MARCOS GONCALVES; DE SOUZA TEIXEIRA, ALEXANDRE ABILIO; LIRA, FABIO SANTOS; YOUNGSTEDT, SHAWN D.; THOMATIELI DOS SANTOS, RONALDO VAGNER; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Exercise Improves Immune Function, Antidepressive Response, and Sleep Quality in Patients with Chronic Primary Insomnia. BIOMED RESEARCH INTERNATIONAL, 2014. (98/14303-3, 08/02862-1)

ESTEVES, A. MACULANO; ACKEL-D'ELIA, C.; TUFIK, S.; DE MELLO, M. T.. Sleep patterns and acute physical exercise: the effects of gender, sleep disturbances, type and time of physical exercise. JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS, v. 54, n. 6, p. 809-815, DEC 2014. (98/14303-3)

TAKATSU-COLEMAN, ANDRE L.; ZANIN, KARINA A.; PATTI, CAMILLA L.; ZAGER, ADRIANO; LOPES-SILVA, LEONARDO B.; LONGO, BEATRIZ M.; TUFIK, SERGIO; ANDERSEN, MONICA L.; FRUSSA-FILHO, ROBERTO. Short-term sleep deprivation reinstates memory retrieval in mice: The role of corticosterone secretion. PSYCHONEUROENDOCRINOLOGY, v. 38, n. 10, p. 1967-1978, OCT 2013. (98/14303-3)

PERRY, JULIANA C.; BERGAMASCHI, CASSIA T.; CAMPOS, RUY R.; ANDERSEN, MONICA L.; CASARINI, DULCE E.; TUFIK, SERGIO. Differential sympathetic activation induced by intermittent hypoxia and sleep loss in rats: Action of angiotensin (1-7). AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, v. 160, n. 1-2, p. 32-36, FEB 24 2011. (98/14303-3)

CINTRA, FATIMA; TUFIK, SERGIO; D'ALMEIDA, VANIA; CALEGARE, BRUNO F. A.; DE PAOLA, ANGELO; OLIVEIRA, WERCULES; RIZZI, CAMILA; ROIZENBLATT, SUELY; POYARES, DALVA. Cysteine A Potential Biomarker for Obstructive Sleep Apnea. CHEST, v. 139, n. 2, p. 246-252, FEB 2011. (98/14303-3)

HIROTSU, CAMILA; TUFIK, SERGIO; GUINDALINI, CAMILA; MAZZOTTI, DIEGO R.; BITTENCOURT, LIA R.; ANDERSEN, MONICA L.. Association Between Uric Acid Levels and Obstructive Sleep Apnea Syndrome in a Large Epidemiological Sample. PLoS One, v. 8, n. 6, JUN 24 2013. (98/14303-3, 10/50129-1)

MACHADO, RICARDO BORGES; TUFIK, SERGIO; SUCHECKI, DEBORAH. Role of Corticosterone on Sleep Homeostasis Induced by REM Sleep Deprivation in Rats. PLoS One, v. 8, n. 5, MAY 7 2013. (04/02213-2, 98/14303-3)

MACHADO, RICARDO BORGES; TUFIK, SERGIO; SUCHECKI, DEBORAH. Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep-Deprived Rats. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2010. (04/02213-2, 98/14303-3)

CINTRA, FATIMA; AZEREDO BITTENCOURT, LIA RITA; SANTOS-SILVA, ROGERIO; ANDERSEN, MONICA; DE PAOLA, ANGELO; POYARES, DALVA; TUFIK, SERGIO. The association between the Framingham risk score and sleep: A Sao Paulo epidemiological sleep study. Sleep Medicine, v. 13, n. 6, p. 577-582, JUN 2012. (07/50525-1, 98/14303-3)

MAZZOTTI, DIEGO ROBLES; GUINDALINI, CAMILA; LUISA SOSA, ANA; FERRI, CLEUSA P.; TUFIK, SERGIO. Prevalence and correlates for sleep complaints in older adults in low and middle income countries: A 10/66 Dementia Research Group study. Sleep Medicine, v. 13, n. 6, p. 697-702, JUN 2012. (98/14303-3)

SANDAY, LEANDRO; PATTI, CAMILLA L.; ZANIN, KARINA A.; FERNANDES-SANTOS, LUCIANO; OLIVEIRA, LARISSA C.; KAMEDA, SONIA R.; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Ethanol-Induced Memory Impairment in a Discriminative Avoidance Task is State-Dependent. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, v. 37, n. 1, p. E30-E39, JAN 2013. (08/08823-8, 04/14606-9, 98/14303-3)

BEATRIZ DUARTE PALMA; PAULA AYAKO TIBA; RICARDO BORGES MACHADO; SERGIO TUFIK; DEBORAH SUCHECKI. Repercussões imunológicas dos distúrbios do sono: o eixo hipotálamo-pituitária-adrenal como fator modulador. Revista Brasileira de Psiquiatria, v. 29, p. s33-s38, 2007-05-00. (98/14303-3)

GABRIEL NATAN PIRES; SERGIO TUFIK; MONICA LEVY ANDERSEN. Relação entre privação de sono e ansiedade na pesquisa básica. Einstein (São Paulo), v. 10, n. 4, p. 519-523, 2012-12-00. (98/14303-3)

SANDAY, LEANDRO; ZANIN, KARINA A.; PATTI, CAMILLA L.; FERNANDES-SANTOS, LUCIANO; OLIVEIRA, LARISSA C.; LONGO, BEATRIZ M.; ANDERSEN, MONICA L.; TUFIK, SERGIO; FRUSSA-FILHO, ROBERTO. Role of state-dependent learning in the cognitive effects of caffeine in mice. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, v. 16, n. 7, p. 1547-1557, AUG 2013. (98/14303-3)

ALVARENGA, T. A.; RIBEIRO, D. A.; ARAUJO, P.; HIROTSU, C.; MAZARO-COSTA, R.; COSTA, J. L.; BATTISTI, M. C.; TUFIK, S.; ANDERSEN, M. L.. Sleep loss and acute drug abuse can induce DNA damage in multiple organs of mice. HUMAN & EXPERIMENTAL TOXICOLOGY, v. 30, n. 9, p. 1275-1281, SEP 2011. (09/01030-5, 10/50130-0, 98/14303-3, 10/50129-1)

ESUMI, L. A.; PALMA, B. D.; GOMES, V. L.; TUFIK, S.; HIPOLIDE, D. C.. Inflammatory markers are associated with inhibitory avoidance memory deficit induced by sleep deprivation in rats. Behavioural Brain Research, v. 221, n. 1, p. 7-12, AUG 1 2011. (08/51656-5, 98/14303-3)

AZEREDO BITTENCOURT, LIA RITA; PEDRAZZOLI, MARIO; YAGIHARA, FABIANA; LUZ, GABRIELA PONTES; GARBUIO, SILVERIO; MOREIRA, GUSTAVO ANTONIO; PERFEITO, JOAO ALESSIO J.; TUFIK, SERGIO. Late-onset, insidious course and invasive treatment of congenital central hypoventilation syndrome in a case with the Phox2B mutation: case report. Sleep and Breathing, v. 16, n. 4, p. 951-955, DEC 2012. (98/14303-3)

LOPES, CLEIDE; ESTEVES, ANDREA M.; FRUSSA-FILHO, ROBERTO; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Evaluation of periodic limb movements in a putative animal model of restless leg syndrome. MOVEMENT DISORDERS, v. 27, n. 3, p. 413-420, MAR 2012. (08/50646-6, 98/14303-3)

FURTADO, DANIELE; HACHUL, HELENA; ANDERSEN, MONICA L.; CASTRO, RODRIGO A.; GIRAO, MANOEL B.; TUFIK, SERGIO. Nocturia x disturbed sleep: a review. INTERNATIONAL UROGYNECOLOGY JOURNAL, v. 23, n. 3, p. 255-267, MAR 2012. (98/14303-3)

DATTILO, MURILO; MOREIRA ANTUNES, HANNA KAREN; MEDEIROS, ALESSANDRA; MONICO-NETO, MARCOS; SOUZA, HELTON DE S. A.; LEE, KIL SUN; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Paradoxical sleep deprivation induces muscle atrophy. MUSCLE & NERVE, v. 45, n. 3, p. 431-433, MAR 2012. (09/11056-1, 98/14303-3)

FRANK, MIRIAM K.; ESTEVES, ANDREA MACULANO; LOPES, CLEIDE; CAVAGNOLLI, DANIEL A.; TUFIK, SERGIO; DE MELLO, MARCO TULIO. The Effects of Physical Exercise on the Serum Iron Profile in Spontaneously Hypertensive Rats. BIOLOGICAL TRACE ELEMENT RESEARCH, v. 145, n. 2, p. 222-224, FEB 2012. (08/50646-6, 98/14303-3)

VALVERDE ZANINI, GISLAINE DE ALMEIDA; TUFIK, SERGIO; ANDERSEN, MONICA LEVY; MARTINS DA SILVA, RAQUEL CRISTINA; AMODEO BUENO, ORLANDO FRANCISCO; RODRIGUES, CAMILA CRUZ; POMPEIA, SABINE. Free Recall of Word Lists under Total Sleep Deprivation and after Recovery Sleep. Sleep, v. 35, n. 2, p. 223-230, FEB 1 2012. (06/58276-8, 98/14303-3, 08/08921-0)

ARMANI, FERNANDA; ANDERSEN, MONICA L.; ANDREATINI, ROBERTO; FRUSSA-FILHO, ROBERTO; TUFIK, SERGIO; FERNANDES GALDUROZ, JOSE CARLOS. Successful Combined Therapy with Tamoxifen and Lithium in a Paradoxical Sleep Deprivation-Induced Mania Model. CNS Neuroscience & Therapeutics, v. 18, n. 2, p. 119-125, 2012. (98/14303-3)

GUARINIELLO, LUCIANA DORIA; VICARI, PERLA; LEE, KIL SUN; DE OLIVEIRA, ALLAN CHIARATTI; TUFIK, SERGIO. Bone Marrow and Peripheral White Blood Cells Number is Affected by Sleep Deprivation in a Murine Experimental Model. Journal of Cellular Physiology, v. 227, n. 1, p. 361-366, JAN 2012. (98/14303-3)

MARTINS, PAULO J. F.; FERNANDES, LEANDRO; DE OLIVEIRA, ALLAN C.; TUFIK, SERGIO; D'ALMEIDA, VANIA. Type of diet modulates the metabolic response to sleep deprivation in rats. NUTRITION & METABOLISM, v. 8, DEC 12 2011. (98/14303-3)

CRISPIM, CIBELE APARECIDA; ZIMBERG, IONA ZALCMAN; DOS REIS, BRUNO GOMES; DINIZ, RAFAEL MARQUES; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Relationship between Food Intake and Sleep Pattern in Healthy Individuals. JOURNAL OF CLINICAL SLEEP MEDICINE, v. 7, n. 6, p. 659-664, 2011. (98/14303-3)

PAPALE, LIGIA A.; BEYER, BARBARA; JONES, JULIE M.; SHARKEY, LISA M.; TUFIK, SERGIO; EPSTEIN, MICHAEL; LETTS, VERITY A.; MEISLER, MIRIAM H.; FRANKEL, WAYNE N.; ESCAYG, ANDREW. Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice. Human Molecular Genetics, v. 18, n. 9, p. 1633-1641, MAY 1 2009. (07/50534-0, 98/14303-3)

MARTINS‚ P.J.F.; GALDIERI‚ L.C.; SOUZA‚ F.G.; ANDERSEN‚ M.L.; BENEDITO-SILVA‚ A.A.; TUFIK‚ S.; D’ALMEIDA‚ V.. Physiological variation in plasma total homocysteine concentrations in rats. Life Sciences, v. 76, n. 22, p. 2621-2629, 2005. (01/11365-2, 98/14303-3)

GUINDALINI, CAMILA; ANDERSEN, MONICA L.; ALVARENGA, TATHIANA; LEE, KIL; TUFIK, SERGIO. To what extent is sleep rebound effective in reversing the effects of paradoxical sleep deprivation on gene expression in the brain?. Behavioural Brain Research, v. 201, n. 1, p. 53-58, July 2009. (06/58274-5, 98/14303-3)

PAPALE, LIGIA A.; MAKINSON, CHRISTOPHER D.; EHLEN, J. CHRISTOPHER; TUFIK, SERGIO; DECKER, MICHAEL J.; PAUL, KETEMA N.; ESCAYG, ANDREW. Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+). Epilepsia, v. 54, n. 4, p. 625-634, APR 2013. (07/50534-0, 98/14303-3)

SILVA, ANDRESSA; DE QUEIROZ, SANDRA SOUZA; ANDERSEN, MONICA LEVY; MONICO-NETO, MARCOS; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; ROIZENBLATT, SUELY; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Passive body heating improves sleep patterns in female patients with fibromyalgia. Clinics, v. 68, n. 2, p. 135-139, 2013. (07/56620-6, 09/13881-0, 98/14303-3)

DA SILVA, PATRICIA LEAO; DE MELLO, MARCO TULIO; CHEIK, NADIA CARLA; SANCHES, PRISCILA LIMA; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; CARNIER, JUNE; INOUE, DANIELA; DO NASCIMENTO, CLAUDIA M. O.; OYAMA, LILA M.; TOCK, LIAN; et al. Reduction in the Leptin Concentration as a Predictor of Improvement in Lung Function in Obese Adolescents. Obesity Facts, v. 5, n. 6, p. 806-820, DEC 2012. (06/00684-3, 08/53069-0, 98/14303-3)

SANTOS-SILVA, ROGERIO; AZEREDO BITTENCOURT, LIA RITA; NOGUEIRA PIRES, MARIA LAURA; DE MELLO, MARCO TULIO; TADDEI, JOSE AUGUSTO; BENEDITO-SILVA, ANA AMELIA; POMPEIA, CELINE; TUFIK, SERGIO. Increasing trends of sleep complaints in the city of Sao Paulo, Brazil. Sleep Medicine, v. 11, n. 6, p. 520-524, JUN 2010. (07/50525-1, 98/14303-3)

TUFIK, SERGIO; SANTOS-SILVA, ROGERIO; TADDEI, JOSE AUGUSTO; AZEREDO BITTENCOURT, LIA RITA. Obstructive Sleep Apnea Syndrome in the Sao Paulo Epidemiologic Sleep Study. Sleep Medicine, v. 11, n. 5, p. 441-446, MAY 2010. (07/50525-1, 98/14303-3)

SILVA, ANDRESSA; ARAUJO, PAULA; ZAGER, ADRIANO; TUFIK, SERGIO; ANDERSEN, MONICA LEVY. Sex differences in sleep pattern of rats in an experimental model of osteoarthritis. EUROPEAN JOURNAL OF PAIN, v. 15, n. 6, p. 545-553, JUL 2011. (07/56620-6, 06/58275-1, 10/50130-0, 98/14303-3)

MAZARO-COSTA, RENATA; ANDERSEN, MONICA L.; HACHUL, HELENA; TUFIK, SERGIO. Medicinal Plants as Alternative Treatments for Female Sexual Dysfunction: Utopian Vision or Possible Treatment in Climacteric Women?. Journal of Sexual Medicine, v. 7, n. 11, p. 3695-3714, NOV 2010. (98/14303-3)

MATOS, GABRIELA; ANDERSEN, MONICA L.; DO VALLE, ANGELA CRISTINA; TUFIK, SERGIO. The relationship between sleep and epilepsy: Evidence from clinical trials and animal models. JOURNAL OF THE NEUROLOGICAL SCIENCES, v. 295, n. 1-2, p. 1-7, AUG 15 2010. (98/14303-3)

ANDERSEN, MONICA L.; GUINDALINI, CAMILA; SANTOS-SILVA, ROGERIO; BITTENCOURT, LIA R. A.; TUFIK, SERGIO. Angiotensin-Converting Enzyme Polymorphism and Erectile Dysfunction Complaints in the Brazilian Population. Journal of Sexual Medicine, v. 7, n. 8, p. 2791-2797, AUG 2010. (98/14303-3)

ALVARENGA, TATHIANA A.; ANDERSEN, MONICA L.; TUFIK, SERGIO. Influence of Progesterone on Sexual Performance in Male Rats. Journal of Sexual Medicine, v. 7, n. 7, p. 2435-2444, JUL 2010. (09/01030-5, 98/14303-3)

CAMPOS-DE-SOUSA, SARA; GUINDALINI, CAMILA; TONDO, LEONARDO; MUNRO, JANET; OSBORNE, SARAH; FLORIS, GIANFRANCO; PEDRAZZOLI, MARIO; TUFIK, SERGIO; BREEN, GEROME; COLLIER, DAVID. Nuclear Receptor Rev-Erb-alpha Circadian Gene Variants and Lithium Carbonate Prophylaxis in Bipolar Affective Disorder. JOURNAL OF BIOLOGICAL RHYTHMS, v. 25, n. 2, p. 132-137, APR 2010. (98/14303-3)

FORCINA MARTINS, PAULO JOSE; MARQUES, MARINA SOARES; TUFIK, SERGIO; D'ALMEIDA, VANIA. Orexin activation precedes increased NPY expression, hyperphagia, and metabolic changes in response to sleep deprivation. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 298, n. 3, p. E726-E734, MAR 2010. (98/14303-3)

ANDERSEN, MONICA L.; RIBEIRO, DANIEL A.; ALVARENGA, TATHIANA A.; SILVA, ANDRESSA; ARAUJO, PAULA; ZAGER, ADRIANO; TENORIO, NEULI M.; TUFIK, SERGIO. Are endogenous sex hormones related to DNA damage in paradoxically sleep-deprived female rats?. Hormones and Behavior, v. 57, n. 2, p. 216-221, FEB 2010. (09/01030-5, 06/58275-1, 07/01228-4, 98/14303-3)

ANDERSEN, MONICA L.; LEE, KIL S.; GUINDALINI, CAMILA; LEITE, WALDEMARKS A.; BIGNOTTO, MAGDA; TUFIK, SERGIO. Altered Sleep Patterns and Physiologic Characteristics in Spontaneous Dwarf Rats. COMPARATIVE MEDICINE, v. 59, n. 4, p. 344-349, AUG 2009. (98/14303-3)

LEE, KIL S.; ALVARENGA, TATHIANA A.; GUINDALINI, CAMILA; ANDERSEN, MONICA L.; CASTRO, ROSA M. R. P. S.; TUFIK, SERGIO. Validation of commonly used reference genes for sleep-related gene expression studies. BMC MOLECULAR BIOLOGY, v. 10, MAY 15 2009. (06/58274-5, 98/14303-3)

ANDERSEN, MONICA L.; MARGIS, REGINA; FREY, BENICIO N.; GIGLIO, LARRIANY M. F.; KAPCZINSKI, FLAVIO; TUFIK, SERGIO. Electrophysiological correlates of sleep disturbance induced by acute and chronic administration of D-amphetamine. Brain Research, v. 1249, p. 162-172, JAN 16 2009. (98/14303-3)

ANDERSEN, MONICA L.; GUINDALINI, CAMILA; SANTOS-SILVA, ROGERIO; BITTENCOURT, LIA RITA A.; TUFIK, SERGIO. Association Analysis of Endothelial Nitric Oxide Synthase G894T Gene Polymorphism and Erectile Dysfunction Complaints in a Population-Based Survey. Journal of Sexual Medicine, v. 7, n. 3, p. 1229-1236, MAR 2010. (07/50525-1, 98/14303-3)

MARTINS, R. C. S.; ANDERSEN, M. L.; GARBUIO, S. A.; BITTENCOURT, L. R.; GUINDALINI, C.; SHIH, M. C.; HOEXTER, M. Q.; BRESSAN, R. A.; CASTIGLIONI, M. L. V.; TUFIK, S.. Dopamine Transporter Regulation during Four Nights of REM Sleep Deprivation Followed by Recovery - An in vivo Molecular Imaging Study in Humans. Sleep, v. 33, n. 2, p. 243-251, FEB 1 2010. (06/58276-8, 98/14303-3)

POMPEIA, SABINE; GREGO, BRUNO H. C.; PRADELLA-HALLINAN, MARCIA; HACHUL, HELENA; TUFIK, SERGIO; D'ALMEIDA, VANIA. Acute benzodiazepine administration induces changes in homocysteine metabolism in young healthy volunteers. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 33, n. 6, p. 933-938, AUG 31 2009. (03/00046-9, 05/03552-8, 98/14303-3)

ALVES, EDUARDO DA SILVA; ACKEL-D'ELIA, CAROLINA; LUZ, GABRIELA PONTES; ABRAHAO CUNHA, THAYS CROSARA; CARNEIRO, GLAUCIA; TUFIK, SERGIO; AZEREDO BITTENCOURT, LIA RITA; DE MELLO, MARCO TULIO. Does physical exercise reduce excessive daytime sleepiness by improving inflammatory profiles in obstructive sleep apnea patients?. Sleep and Breathing, v. 17, n. 2, p. 505-510, MAY 2013. (03/11037-0, 98/14303-3)

MATOS, GABRIELA; SCORZA, FULVIO A.; CAVALHEIRO, ESPER A.; TUFIK, SERGIO; ANDERSEN, MONICA L.. PDEI-5 for Erectile Dysfunction: A Potential Role in Seizure Susceptibility. Journal of Sexual Medicine, v. 9, n. 8, p. 2111-2121, AUG 2012. (98/14303-3, 10/15110-8)

RUIZ, FRANCIELI S.; ANDERSEN, MONICA L.; MARTINS, RAQUEL C. S.; ZAGER, ADRIANO; LOPES, JOSE D.; TUFIK, SERGIO. Immune alterations after selective rapid eye movement or total sleep deprivation in healthy male volunteers. Innate Immunity, v. 18, n. 1, p. 44-54, FEB 2012. (06/58275-1, 07/55445-6, 98/14303-3)

ARAUJO, P.; HACHUL, H.; SANTOS-SILVA, R.; BITTENCOURT, L. R. A.; TUFIK, S.; ANDERSEN, M. L.. Sleep pattern in women with menstrual pain. Sleep Medicine, v. 12, n. 10, p. 1028-1030, DEC 2011. (10/50130-0, 98/14303-3)

GINANI, G. E.; TUFIK, S.; BUENO, O. F. A.; PRADELLA-HALLINAN, M.; RUSTED, J.; POMPEIA, S.. Acute effects of donepezil in healthy young adults underline the fractionation of executive functioning. JOURNAL OF PSYCHOPHARMACOLOGY, v. 25, n. 11, p. 1508-1516, NOV 2011. (98/14303-3)

ROIZENBLATT, SUELY; ANDERSEN, MONICA L.; BIGNOTTO, MAGDA; D'ALMEIDA, VANIA; MARTINS, PAULO J. F.; TUFIK, SERGIO. Neonatal arthritis disturbs sleep and behaviour of adult rat offspring and their dams. EUROPEAN JOURNAL OF PAIN, v. 14, n. 10, p. 985-991, NOV 2010. (98/14303-3)

SANTOS COELHO, FERNANDO MORGADINHO; PRADELLA-HALLINAN, MARCIA; PEDRAZZOLI, MARIO; SENNE SOARES, CARLOS AUGUSTO; PERES FERNANDES, GUSTAVO BRUNIERA; GONCALVES, ANDRE LEITE; TUFIK, SERGIO; AZEREDO BITTENCOURT, LIA RITA. Traditional biomarkers in narcolepsy Experience of a brazilian sleep centre. Arquivos de Neuro-Psiquiatria, v. 68, n. 5, p. 712-715, OCT 2010. (98/14303-3)

ANDREAZZA, ANA C.; ANDERSEN, MONICA L.; ALVARENGA, TATHIANA A.; DE-OLIVEIRA, MARCOS R.; ARMANI, FERNANDA; RUIZ, FRANCIELI S.; GIGLIO, LARRIANY; MOREIRA, JOSE C. F.; KAPCZINSKI, FLAVIO; TUFIK, SERGIO. Impairment of the mitochondrial electron transport chain due to sleep deprivation in mice. JOURNAL OF PSYCHIATRIC RESEARCH, v. 44, n. 12, p. 775-780, SEP 2010. (09/01030-5, 98/14303-3)

PALMA, BEATRIZ DUARTE; TUFIK, SERGIO. Increased Disease Activity is Associated with Altered Sleep Architecture in an Experimental Model of Systemic Lupus Erythematosus. Sleep, v. 33, n. 9, p. 1244-1248, SEP 1 2010. (06/57158-1, 98/14303-3)

PAPALE, L. A.; ANDERSEN, M. L.; PERRY, J. C.; TUFIK, S.. Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats. Brazilian Journal of Medical and Biological Research, v. 41, n. 9, p. 782-788, SEP 2008. (04/04008-7, 98/14303-3)

HACHUL, HELENA; OLIVEIRA, DENISE; TUFIK, SERGIO; BITTENCOURT, LIA. Effect of massage in postmenopausal women with insomnia - A pilot study. Clinics, v. 66, n. 2, p. 343-346, 2011. (98/14303-3)

DATTILO, MURILO; CRISPIM, CIBELE APARECIDA; ZIMBERG, IONA ZALCMAN; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Meal distribution across the day and its relationship with body composition. Biological Rhythm Research, v. 42, n. 2, p. 119-129, 2011. (09/11056-1, 98/14303-3)

DE SOUZA, LUCIANE; ANDERSEN, MONICA L.; SMAILI, SORAYA S.; LOPES, GUIOMAR S.; HO, PRISCILA S.; PAPALE, LIGIA A.; TUFIK, SERGIO. Age-related changes during a paradigm of chronic sleep restriction. Behavioural Brain Research, v. 214, n. 2, p. 201-205, DEC 10 2010. (08/50424-3, 98/14303-3)

LUCCHESI, LIGIA MENDONCA; SPECIALI, JOSE GERALDO; SANTOS-SILVA, ROGERIO; TADDEI, JOSE AUGUSTO; TUFIK, SERGIO; AZEREDO BITTENCOURT, LIA RITA. Nocturnal awakening with headache and its relationship with sleep disorders in a population-based sample of adult inhabitants of Sao Paulo City, Brazil. CEPHALALGIA, v. 30, n. 12, p. 1477-1485, DEC 2010. (07/50525-1, 98/14303-3)

ROIZENBLATT, SUELY; GUILLEMINAULT, CHRISTIAN; POYARES, DALVA; CINTRA, FÁTIMA; KAUATI, ADRIANA; TUFIK, SERGIO. A double-blind, placebo-controlled, crossover study of sildenafil in obstructive sleep apnea. Archives of Internal Medicine, v. 166, n. 16, p. 1763-1767, Sept. 2006. (98/14303-3)

FREIRE, ANAFLÁVIA O.; SUGAI, GISELE C. M.; CHRISPIN, FERNANDA SILVEIRA; TOGEIRO, SÔNIA MARIA; YAMAMURA, YSAO; MELLO, LUIZ EUGÊNIO; TUFIK, SÉRGIO. Treatment of moderate obstructive sleep apnea syndrome with acupuncture: a randomised, placebo-controlled pilot trial. Sleep Medicine, v. 8, n. 1, p. 43-50, Jan. 2007. (01/08063-4, 98/14303-3)

M.L.N. PIRES; A.A. BENEDITO-SILVA; M.T. MELLO; S. DEL GIGLIO; C. POMPEIA; S. TUFIK. Sleep habits and complaints of adults in the city of São Paulo, Brazil, in 1987 and 1995. Brazilian Journal of Medical and Biological Research, v. 40, n. 11, p. 1505-1515, 2007-10-22. (98/14303-3)

DE MELLO, M. T.; ESTEVES, A. M.; PIRES, M. L. N.; SANTOS, D. C.; BITTENCOURT, L. R. A.; SILVA, R. S.; TUFIK, S.. Relationship between Brazilian airline pilot errors and time of day. Brazilian Journal of Medical and Biological Research, v. 41, n. 12, p. 1129-1131, Dec. 2008. (98/14303-3)

MARTINS‚ P.J.F.; D’ALMEIDA‚ V.; PEDRAZZOLI‚ M.; LIN‚ L.; MIGNOT‚ E.; TUFIK‚ S.. Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regulatory Peptides, v. 117, n. 3, p. 155-158, 2004. (98/14303-3)

LOPES‚ M.C.; ROSA‚ A.; ROIZENBLATT‚ S.; GUILLEMINAULT‚ C.; PASSARELLI‚ C.; TUFIK‚ S.; POYARES‚ D.; OTHERS. Cyclic alternating pattern in peripubertal children. Sleep, v. 28, n. 2, p. 215, 2005. (98/14303-3)

MOREIRA‚ K.M.; HIPÓLIDE‚ D.C.; NOBREGA‚ J.N.; BUENO‚ O.F.A.; TUFIK‚ S.; GABRIELA M OLIVEIRA‚ M.. Deficits in avoidance responding after paradoxical sleep deprivation are not associated with altered [3H] pirenzepine binding to M1 muscarinic receptors in rat brain. Brain Research, v. 977, n. 1, p. 31-37, 2003. (98/14303-3)

PEDRAZZOLI‚ M.; LOUZADA‚ F.M.; PEREIRA‚ D.S.; BENEDITO-SILVA‚ A.A.; LOPEZ‚ A.R.; MARTYNHAK‚ B.J.; KORCZAK‚ A.L.; KOIKE‚ B.D.V.; BARBOSA‚ A.A.; D’ALMEIDA‚ V.; et al. Clock polymorphisms and circadian rhythms phenotypes in a sample of the Brazilian population. CHRONOBIOLOGY INTERNATIONAL, v. 24, n. 1, p. 1-8, 2007. (98/14303-3)

ANDERSEN‚ M.L.; BIGNOTTO‚ M.; PAPALE‚ L.A.; TUFIK‚ S.. Age-related effects on genital reflexes induced by paradoxical sleep deprivation and cocaine in rats. Experimental Gerontology, v. 39, n. 2, p. 233-237, 2004. (98/14303-3)

BITTENCOURT‚ L.R.A.; PEDRAZZOLI‚ M.; YAGIHARA‚ F.; LUZ‚ G.P.; GARBUIO‚ S.; MOREIRA‚ G.A.; PERFEITO‚ J.A.J.; TUFIK‚ S.. Late-onset‚ insidious course and invasive treatment of congenital central hypoventilation syndrome in a case with the Phox2B mutation: case report. Sleep and Breathing, p. 1-5, 2011. (98/14303-3)

ANDERSEN‚ M.L.; BIGNOTTO‚ M.; TUFIK‚ S.. The effect of apomorphine on genital reflexes in male rats deprived of paradoxical sleep. Physiology & Behavior, v. 80, n. 2-3, p. 211-215, 2003. (98/14303-3)

ANDERSEN‚ M.L.; BIGNOTTO‚ M.; TUFIK‚ S.. Influence of paradoxical sleep deprivation and cocaine on development of spontaneous penile reflexes in rats of different ages. Brain Research, v. 968, n. 1, p. 130-138, 2003. (98/14303-3)

ANDERSEN‚ M.L.; TUFIK‚ S.. Does male sexual behavior require progesterone?. BRAIN RESEARCH REVIEWS, v. 51, n. 1, p. 136-143, 2006. (98/14303-3)

SILVA‚ R.H.; KAMEDA‚ S.R.; CARVALHO‚ R.C.; TAKATSU-COLEMAN‚ A.L.; NIIGAKI‚ S.T.; ABÍLIO‚ V.C.; TUFIK‚ S.; FRUSSA-FILHO‚ R.. Anxiogenic effect of sleep deprivation in the elevated plus-maze test in mice. Psychopharmacology, v. 176, n. 2, p. 115-122, 2004. (98/14303-3, 01/10713-7)

MACHADO‚ R.B.; SUCHECKI‚ D.; TUFIK‚ S.. Sleep homeostasis in rats assessed by a long-term intermittent paradoxical sleep deprivation protocol. Behavioural Brain Research, v. 160, n. 2, p. 356-364, 2005. (98/14303-3)

PALMA‚ B.D.; SUCHECKI‚ D.; CATALLANI‚ B.; TUFIK‚ S.. Effect of sleep deprivation on the corticosterone secretion in an experimental model of autoimmune disease. NEUROIMMUNOMODULATION, v. 14, n. 2, p. 72-77, 2007. (98/14303-3, 01/07263-0)

MACHADO, RICARDO BORGES; TUFIK, SERGIO; SUCHECKI, DEBORAH. Chronic stress during paradoxical sleep deprivation increases paradoxical sleep rebound: Association with prolactin plasma levels and brain serotonin content. PSYCHONEUROENDOCRINOLOGY, v. 33, n. 9, p. 1211-1224, 2008. (04/02213-2, 98/14303-3)

PALMA, B. D.; NOBREGA, J. N.; GOMES, V. L.; ESUMI, L. A.; SEABRA, M. L. V.; TUFIK, S.; HIPOLIDE, D. C.. Prostaglandin involvement in hyperthermia induced by sleep deprivation: A pharmacological and autoradiographic study. Life Sciences, v. 84, n. 9-10, p. 278-281, FEB 27 2009. (98/14303-3)

HACHUL, HELENA; BRANDAO, LETICIA DE C.; BITTENCOURT, LIA R. A.; D'ALMEIDA, VANIA; ANDERSEN, MONICA L.; BARACAT, EDMUND C.; TUFIK, SERGIO. Clinical profile of menopausal insomniac women referred to sleep laboratory. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, v. 88, n. 4, p. 422-427, 2009. (98/14303-3)

ANDERSEN‚ M.L.; TUFIK‚ S.. Sleep patterns over 21-day period in rats with chronic constriction of sciatic nerve. Brain Research, v. 984, n. 1, p. 84-92, 2003. (96/08878-8, 98/14303-3)

MARTINS‚ PJF; NOBREGA‚ JN; TUFIK‚ S.; D’ALMEIDA‚ V.. Sleep deprivation-induced gnawing—relationship to changes in feeding behavior in rats. Physiology & Behavior, v. 93, n. 1, p. 229-234, 2008. (98/14303-3)

ZIMBERG, IONA ZALCMAN; DAMASO, ANA; DEL RE, MARIANA; CARNEIRO, ALINE MILLANI; SOUZA, HELTON DE SA; DE LIRA, FABIO SANTOS; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Short sleep duration and obesity: mechanisms and future perspectives. Cell Biochemistry and Function, v. 30, n. 6, p. 524-529, AUG 2012. (08/09565-2, 98/14303-3, 09/05657-2, 06/00684-3, 08/53069-0)

TENORIO, NEULI M.; RIBEIRO, DANIEL A.; ALVARENGA, TATHIANA A.; FRACALOSSI, ANA CAROLINA C.; CARLIN, VIVIANE; HIROTSU, CAMILA; TUFIK, SERGIO; ANDERSEN, MONICA L.. The influence of sleep deprivation and obesity on DNA damage in female Zucker rats. Clinics, v. 68, n. 3, p. 385-389, 2013. (98/14303-3, 09/03360-2, 11/12325-6, 07/01228-4, 10/50129-1)

TERESA CRISTINA BARROS SCHUTZ; THAYS CROSARA ABRAHAO CUNHA; THAIS MOURA-GUIMARAES; GABRIELA PONTES LUZ; CAROLINA ACKEL-D'ELIA; EDUARDO DA SILVA ALVES; GILBERTO PANTIGA JUNIOR; MARCO TULIO DE MELLO; SERGIO TUFIK; LIA BITTENCOURT. Comparison of the effects of continuous positive airway pressure, oral appliance and exercise training in obstructive sleep apnea syndrome. Clinics, v. 68, n. 8, p. 1168-1174, 2013-00-00. (09/01031-1, 98/14303-3)

C.M. QUEIROZ; P.A. TIBA; K.M. MOREIRA; P.A.M. GUIDINE; G.H.S. REZENDE; M.F.D. MORAES; M.A.M. PRADO; V.F. PRADO; S. TUFIK; L.E. MELLO. Sleep pattern and learning in knockdown mice with reduced cholinergic neurotransmission. Brazilian Journal of Medical and Biological Research, v. 46, n. 10, p. 844-854, 2013-10-00. (98/14303-3)

PEREIRA, D. S.; VAN DER VEEN, D. R.; GONCALVES, B. S. B.; TUFIK, S.; VON SCHANTZ, M.; ARCHER, S. N.; PEDRAZZOLI, M.. The Effect of Different Photoperiods in Circadian Rhythms of Per3 Knockout Mice. BIOMED RESEARCH INTERNATIONAL, 2014. (98/14303-3, 07/05037-9)