Green synthesis of silver nanoparticles combined to calcium glycerophosphate: antimicrobial and antibiofilm activities

Autor(es):Mostrar menos -

Souza, Jose A. S. ^[1] ; Barbosa, Debora B. ^[2] ; Berretta, Andresa A. ^[3] ; do Amaral, Jackeline G. ^[1] ; Gorup, Luiz F. ^[4] ; de Souza Neto, Francisco N. ^[4] ; Fernandes, Renan A. ^[2] ; Fernandes, Gabriela L. ^[2] ; Camargo, Emerson R. ^[4] ; Agostinho, Alessandra M. ^[5] ; Delbem, Alberto C. B. ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Sch Dent, Dept Pediat Dent & Publ Hlth, BR-16015050 Aracatuba, SP - Brazil

^[2] Sao Paulo State Univ UNESP, Sch Dent, Dept Dent Mat & Prosthodont, BR-16015050 Aracatuba, SP - Brazil

^[3] APIS FLORA INDL COML LTDA, Lab Res Dev & Innovat, BR-14020670 Ribeirao Preto, SP - Brazil

^[4] Univ Fed Sao Carlos, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil

^[5] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 - USA

• Tipo de documento: Artigo Científico
• Fonte: FUTURE MICROBIOLOGY; v. 13, n. 3, p. 345-357, MAR 2018.
• Citações Web of Science: 1

Resumo

Aim: To synthesize, characterize and evaluate the antimicrobial and antibiofilm activities of novel nanocomposites containing silver nanoparticles (AgNPs) associated or not to 8-calcium glycerophosphate. Materials \& methods: These nanocomposites were produced through a `green' route using extracts of different parts of pomegranate. Antimicrobial and antibiofilm properties against Candida albicans and Streptococcus mutans were determined by the minimum bactericidal/fungicidal concentration and biofilm density after treatments. Results: All extracts used were successful in producing AgNPs. Composites made with peel extracts showed the highest antimicrobial and antibiofilm activity against both microorganisms tested and performed similarly or even better than chlorhexidine. Conclusion: AgNPs associated or not to calcium glycerophosphate produced by a `green' process may be a promising novel antimicrobial agent against oral microorganisms. (AU)

• Processo FAPESP: 15/00825-5 - Efeito do glicerofosfato de cálcio associado a nanopartículas de prata obtidas pela síntese 'Green' sobre biofilmes de Candida albicans e Streptococcus mutans
• Beneficiário: José Antonio Santos Souza
• Modalidade de apoio: Bolsas no Brasil - Doutorado