Flavonols from Annona coriacea Mart. (Annonaceae)

Autor(es)

Novaes, Paula ^[1] ; Pena Ferreira, Marcelo J. ^[1] ; Alves Cursino dos Santos, Deborah Yara ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Biociencias, Rua Matao 277, BR-05508090 Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Biochemical Systematics and Ecology; v. 78, p. 77-80, JUN 2018.
• Citações Web of Science: 3

Resumo

Annona is one of the largest genus of Annonaceae. Flavonol derivatives have the major occurrence in the family and in Annona. Glycosides of quercetin, kaempferol and isorhamnetin have been isolated and identified more frequently than any other flavonols. Annona coriacea Mart. is a perennial shrub native to the Brazilian savanna. The species has some acetogenins, alkaloids, diterpenes, polyphenols, flavonoids and volatile compounds already identified. We isolated 11 flavonols from A. coriacea leaves: 1 - quercetin-3-O-beta-(6{''}-O-beta-glucosyl)-glucoside (quercetin-3-O-gentiobioside), 2 - quercetin-3-O-beta-(6{''}-O-alpha-rhamnosyl)-galactoside (quercetin-3-O-robinobioside), 3 - quercetin 3-O-beta-(6{''}-O-alpha-rhamnosyl) glucoside (rutin), 4 - quercetin-3-O-beta-galactoside (hyperin), 5- quercetin-3-O-beta-glucoside (isoquercitrin), 6 - kaempferol-3-O-beta-(6{''}-O-alpha-rhamnosyl)-galactoside (biorobin), 7 - kaempferol-3-O-beta-(6{''}-O-alpha-rhamnosyl)-glucoside (nicotiflorin), 8 - isorhamnetin-3-O-beta-(6{''}-O-alpha-rhamnosyl)galactoside (keioside), 9 - isorhamnetin-3-O-beta-(6{''}-O-alpha-rhamnosyl)-glucoside (narcissin), 10 - isorhamnetin-3-O-beta-galactoside (cacticin), 11 - isorhamnetin-3-O-beta-glucoside. Quercetin derivatives were predominant, followed by isorhamnetin and kaempferol ones. All flavonols, except 3, have never been described in A. coriacea. Compound 10 was isolated only once in another species of the family. Compounds 8 and 9 are described for the first time in Annonaceae. The occurrence of flavonol derivatives as the main flavonoids could confirm that the family represents a basal evolutionary state. (AU)

• Processo FAPESP: 13/07543-0 - Atividades pesticida de acetogeninas de espécies de Annonaceae nativas do Cerrado
• Beneficiário: Déborah Yara Alves Cursino dos Santos
• Modalidade de apoio: Auxílio à Pesquisa - Regular