Optimizing loop-type cryogenic modulation in comprehensive two-dimensional gas chromatography using time-variable combination of the dual-stage jets for analysis of crude oil

Autor(es)

Alexandrino, Guilherme L. ^[1] ; de Sousa Junior, Gustavo R. ^[1] ; Reis, Francisco de A. M. ^[1] ; Augusto, Fabio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Estadual Campinas, Inst Chem, Cidade Univ Zeferino Vaz, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Chromatography A; v. 1536, p. 82-87, FEB 9 2018.
• Citações Web of Science: 5

Resumo

The enhanced chromatographic capability of the comprehensive two-dimensional gas chromatography (GC x GC) has already found several applications in analytical chemistry comprising complex samples. However, setting the appropriate chromatographic conditions that maximize sensitivity and separation efficiency in GC x GC may be more difficult than in conventional one-dimension gas chromatography, mainly due to the additional parameters strictly related to the modulation. Loop-type cryogenic modulators have been currently used for crude oil analysis using GC x GC, requiring sometimes a laborious try-and-error procedure to properly tune the dual jets elapsed times on modulation. In this work, the advantages of choosing a time-variable combination of cold and hot jets pulses in a loop-type cryogenic modulator is presented when performing the fingerprinting analysis of crude oils using GC x GC-QMS, contrary to the conventional procedure based on a single combination for the dual-stage jets. A design of experiments approach is proposed to most effectively optimize the time-variable combination of the dual-jets elapsed times while modulating the wide hydrocarbons range along the GC x GC analysis. The most abundant classes of hydrocarbons contained in the maltenes fraction of a crude oil sample, such as paraffins, aromatics, steranes and hopanes were successfully resolved. (C) 2017 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 15/08201-0 - Petroleômica: uma abordagem utilizando a cromatografia bidimensional "abrangente" acoplada à espectrometria de massas e a quimiometria
• Beneficiário: Guilherme Lionello Alexandrino
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado